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Protein
Submitted name:

Ectodysplasin receptor

Gene

edar

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • signaling receptor activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Ectodysplasin receptorImported
Gene namesi
Name:edarImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-070117-2062 edar

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei183 – 210HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500275850927 – 459Sequence analysisAdd BLAST433

Structurei

3D structure databases

ProteinModelPortaliB0YIF2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili224 – 251Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGTD Eukaryota
ENOG41104RU LUCA
HOGENOMiHOG000112327
HOVERGENiHBG031530
PhylomeDBiB0YIF2

Family and domain databases

CDDicd13421 TNFRSF_EDAR, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR034052 EDAR_N
SUPFAMiSSF47986 SSF47986, 1 hit

Sequencei

Sequence statusi: Complete.

B0YIF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGHKGGRTPS FLLHFLLVSS MSTVSAEYSS CGENEFYNHT TSSCQPCPQC
60 70 80 90 100
QAGQEPYMNC GYGTKDDDYS CVSCPAGKFS KGKYEICRRH KDCDALYRAT
110 120 130 140 150
VLTPGTSDSD AECGHCLPGY YIQENRPQNI YGMVCHSCQN APRNIKECMR
160 170 180 190 200
STPPASGRAP SVSSSSTTIF PQPEKDPTGQ GHLATALIIA MSTIFIMAIA
210 220 230 240 250
IVMIIMFYIL KSKPSGPVCC SGQLIKAVEA QTNMQEEKKE AQENVVIFQE
260 270 280 290 300
KDEFDKLKPS SPKTAKSEND ASSENEQLLS RSIDSDEEAA QDKQGAADLC
310 320 330 340 350
LLSLVHLTRD KXCXTNTINN NNNHCSRATG IHSRRKKILD LYTKACSVAE
360 370 380 390 400
GLSPTELPFD CLERSSXMLS ATYSTDKAVV KTWRHLAESF GLKRDEIGGM
410 420 430 440 450
TDGMQLFDRI STAGYSIPDL LARLLQIERL DAVETLCCDI LSGTQNCTNP

PLSSRCASV
Length:459
Mass (Da):50,252
Last modified:April 8, 2008 - v1
Checksum:i76438432BBEA0CEC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF137867 mRNA Translation: ABP03881.1
UniGeneiDr.139207

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF137867 mRNA Translation: ABP03881.1
UniGeneiDr.139207

3D structure databases

ProteinModelPortaliB0YIF2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-070117-2062 edar

Phylogenomic databases

eggNOGiENOG410IGTD Eukaryota
ENOG41104RU LUCA
HOGENOMiHOG000112327
HOVERGENiHBG031530
PhylomeDBiB0YIF2

Family and domain databases

CDDicd13421 TNFRSF_EDAR, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR034052 EDAR_N
SUPFAMiSSF47986 SSF47986, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0YIF2_DANRE
AccessioniPrimary (citable) accession number: B0YIF2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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