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UniProtKB - B0X7A5 (B0X7A5_CULQU)

Entry version 71 (19 Jan 2022)
Sequence version 1 (08 Apr 2008)
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Protein

RPB5 homolog

Gene

6048634

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RPB5 homologARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:6048634Imported
ORF Names:CpipJ_CPIJ015285Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7176 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002320 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Partially assembled WGS sequence, Unplaced

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		VectorBase:CPIJ015285

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymeraseImported, NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7176.CPIJ015285-PA

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 94RNA_pol_Rpb5_NInterPro annotationAdd BLAST90
Domaini137 – 209RNA_pol_Rpb5_CInterPro annotationAdd BLAST73

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3218, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_058320_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		B0X7A5

Identification of Orthologs from Complete Genome Data

More...OMAi		VRDRGYF

Database of Orthologous Groups

More...OrthoDBi		1255823at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.1340.10, 1 hit
3.90.940.20, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00025, RNApol_RpoH_RPB5, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR014381, DNA_RNA_pol_RPB5_euk/virus
IPR005571, RNA_pol_Rpb5_N
IPR036710, RNA_pol_Rpb5_N_sf
IPR000783, RNA_pol_subH/Rpb5_C
IPR020608, RNA_pol_subH/Rpb5_CS
IPR039531, Rpb5-like
IPR035913, RPB5-like_sf
IPR020609, RpoH/RPB5

The PANTHER Classification System

More...PANTHERi		PTHR10535, PTHR10535, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01191, RNA_pol_Rpb5_C, 1 hit
PF03871, RNA_pol_Rpb5_N, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000747, RPB5, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53036, SSF53036, 1 hit
SSF55287, SSF55287, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01110, RNA_POL_H_23KD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B0X7A5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDDAETYKL WRIRKTVMQL SHDRGYLVTQ DELDQTLEQF KEQFGDKPSE 
        60         70         80         90        100
KRPARSDLIV LVAHNDDPTD QMFVFFPDEP KIGIKTIKTY CTRMQEENIH 
       110        120        130        140        150
RAIVVVQAGM TPSAKQSLVD MAPKYILEQF LESELLINIT EHELVPEHVV 
       160        170        180        190        200
MTPEEKQELL ARYKLKENML MRIQAGDPVA RYFGLKRGQV VKIIRPSETA 
       210
GRYISYRLVC
Length:210
Mass (Da):24,445
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i90CF9C6D5AFCD4E0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DS232445 Genomic DNA Translation: EDS41858.1

NCBI Reference Sequences

More...RefSeqi		XP_001865530.1, XM_001865495.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		CPIJ015285-RA; CPIJ015285-PA; CPIJ015285

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6048634

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cqu:CpipJ_CPIJ015285

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232445 Genomic DNA Translation: EDS41858.1
RefSeqiXP_001865530.1, XM_001865495.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi7176.CPIJ015285-PA

Genome annotation databases

EnsemblMetazoaiCPIJ015285-RA; CPIJ015285-PA; CPIJ015285
GeneIDi6048634
KEGGicqu:CpipJ_CPIJ015285

Organism-specific databases

VEuPathDBiVectorBase:CPIJ015285

Phylogenomic databases

eggNOGiKOG3218, Eukaryota
HOGENOMiCLU_058320_0_1_1
InParanoidiB0X7A5
OMAiVRDRGYF
OrthoDBi1255823at2759

Family and domain databases

Gene3Di3.40.1340.10, 1 hit
3.90.940.20, 1 hit
HAMAPiMF_00025, RNApol_RpoH_RPB5, 1 hit
InterProiView protein in InterPro
IPR014381, DNA_RNA_pol_RPB5_euk/virus
IPR005571, RNA_pol_Rpb5_N
IPR036710, RNA_pol_Rpb5_N_sf
IPR000783, RNA_pol_subH/Rpb5_C
IPR020608, RNA_pol_subH/Rpb5_CS
IPR039531, Rpb5-like
IPR035913, RPB5-like_sf
IPR020609, RpoH/RPB5
PANTHERiPTHR10535, PTHR10535, 1 hit
PfamiView protein in Pfam
PF01191, RNA_pol_Rpb5_C, 1 hit
PF03871, RNA_pol_Rpb5_N, 1 hit
PIRSFiPIRSF000747, RPB5, 1 hit
SUPFAMiSSF53036, SSF53036, 1 hit
SSF55287, SSF55287, 1 hit
PROSITEiView protein in PROSITE
PS01110, RNA_POL_H_23KD, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB0X7A5_CULQU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B0X7A5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: January 19, 2022
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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