UniProtKB - B0X5P8 (B0X5P8_CULQU)
Protein
Actin-related protein 2/3 complex subunit 4
Gene
6047993
Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Functioni
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.UniRule annotation
GO - Molecular functioni
- actin binding Source: UniProtKB-KW
GO - Biological processi
- actin filament polymerization Source: UniProtKB-UniRule
- Arp2/3 complex-mediated actin nucleation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Actin-bindingUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Actin-related protein 2/3 complex subunit 4UniRule annotation |
Gene namesi | Name:6047993Imported ORF Names:CpipJ_CPIJ014826Imported |
Organismi | Culex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported |
Taxonomic identifieri | 7176 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex › |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton UniRule annotation
Cytoskeleton
- Arp2/3 protein complex Source: UniProtKB-UniRule
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotationInteractioni
GO - Molecular functioni
- actin binding Source: UniProtKB-KW
Protein-protein interaction databases
STRINGi | 7176.CPIJ014826-PA |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1876, Eukaryota |
HOGENOMi | CLU_084855_1_0_1 |
InParanoidi | B0X5P8 |
OMAi | RFMMQRA |
OrthoDBi | 1351067at2759 |
PhylomeDBi | B0X5P8 |
Family and domain databases
Gene3Di | 3.30.1460.20, 1 hit |
InterProi | View protein in InterPro IPR034666, ARPC2/4 IPR008384, ARPC4 |
PANTHERi | PTHR22629, PTHR22629, 1 hit |
Pfami | View protein in Pfam PF05856, ARPC4, 1 hit |
PIRSFi | PIRSF039100, ARPC4, 1 hit |
SUPFAMi | SSF69645, SSF69645, 1 hit |
i Sequence
Sequence statusi: Complete.
B0X5P8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAATLKPYLT AVRHTLTAAM CLTNFSSQVV ERHNKPEVEV RSSKELLLTP
60 70 80 90 100
VVISRNEKER VLIETSVNSV RISIAVKQAD EIEKILCHKF TRFMMMRAEN
110 120 130 140 150
FIILRRKPIE GYDISFLITN FHTEQMYKHK LVDFVIHFME EIDKEISEMK
160
LAVNARARIC SEEFLKRF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS232391 Genomic DNA Translation: EDS40985.1 |
RefSeqi | XP_001864970.1, XM_001864935.1 |
Genome annotation databases
EnsemblMetazoai | CPIJ014826-RA; CPIJ014826-PA; CPIJ014826 |
GeneIDi | 6047993 |
KEGGi | cqu:CpipJ_CPIJ014826 |
VectorBasei | CPIJ014826-RA; CPIJ014826-PA; CPIJ014826 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS232391 Genomic DNA Translation: EDS40985.1 |
RefSeqi | XP_001864970.1, XM_001864935.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7176.CPIJ014826-PA |
Genome annotation databases
EnsemblMetazoai | CPIJ014826-RA; CPIJ014826-PA; CPIJ014826 |
GeneIDi | 6047993 |
KEGGi | cqu:CpipJ_CPIJ014826 |
VectorBasei | CPIJ014826-RA; CPIJ014826-PA; CPIJ014826 |
Phylogenomic databases
eggNOGi | KOG1876, Eukaryota |
HOGENOMi | CLU_084855_1_0_1 |
InParanoidi | B0X5P8 |
OMAi | RFMMQRA |
OrthoDBi | 1351067at2759 |
PhylomeDBi | B0X5P8 |
Family and domain databases
Gene3Di | 3.30.1460.20, 1 hit |
InterProi | View protein in InterPro IPR034666, ARPC2/4 IPR008384, ARPC4 |
PANTHERi | PTHR22629, PTHR22629, 1 hit |
Pfami | View protein in Pfam PF05856, ARPC4, 1 hit |
PIRSFi | PIRSF039100, ARPC4, 1 hit |
SUPFAMi | SSF69645, SSF69645, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B0X5P8_CULQU | |
Accessioni | B0X5P8Primary (citable) accession number: B0X5P8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | December 2, 2020 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |