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Protein
Submitted name:

Sterol regulatory element-binding protein cleavage-activating protein

Gene

6046500

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Sterol regulatory element-binding protein cleavage-activating proteinImported
Gene namesi
Name:6046500Imported
ORF Names:CpipJ_CPIJ013729Imported
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
Proteomesi
  • UP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei296 – 312HelicalSequence analysisAdd BLAST17
Transmembranei324 – 353HelicalSequence analysisAdd BLAST30
Transmembranei359 – 380HelicalSequence analysisAdd BLAST22
Transmembranei407 – 425HelicalSequence analysisAdd BLAST19
Transmembranei731 – 753HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7176.CPIJ013729-PA

Structurei

3D structure databases

ProteinModelPortaliB0X214
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini295 – 453SSDInterPro annotationAdd BLAST159
Domaini792 – 831WD_REPEATS_REGIONInterPro annotationAdd BLAST40
Repeati792 – 831WDPROSITE-ProRule annotationAdd BLAST40
Domaini1113 – 1235WD_REPEATS_REGIONInterPro annotationAdd BLAST123
Repeati1196 – 1235WDPROSITE-ProRule annotationAdd BLAST40

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1933 Eukaryota
ENOG410XR54 LUCA
HOGENOMiHOG000230538
InParanoidiB0X214
OMAiGNFWQND
OrthoDBiEOG091G04AA
PhylomeDBiB0X214

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR030225 SCAP
IPR000731 SSD
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR10796:SF127 PTHR10796:SF127, 1 hit
PfamiView protein in Pfam
PF12349 Sterol-sensing, 1 hit
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 5 hits
SUPFAMiSSF50978 SSF50978, 3 hits
PROSITEiView protein in PROSITE
PS50156 SSD, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

B0X214-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKIWRCCGF NGLKRYPLLN IPLPGTIPTK VVFPYTEQIG QNLHLTNANS
60 70 80 90 100
SSATSEVYNP FSFNGNNIFN IYNISVDPPF PWARIEPLLY VQQIILRSSV
110 120 130 140 150
VPWTSRYNDL QLTDAYRGPL YEVFKLIEIV RNHEDEGSKT TLSDICLHVE
160 170 180 190 200
NVKRPSQQML FPEYNCLLLS PANLWQQNIQ NFNKDSNLLN TVFVNHNLQK
210 220 230 240 250
SKVSTSEMLF GISLRDTGVK RYPMRVRSRI IQYAVTLILR ENNPTFINSL
260 270 280 290 300
KEKLTRTYPL HQSVEDRQQQ QQQQSPLDQS SIMYIFYPGE FDWKEFLPQC
310 320 330 340 350
IAISMLWLYV YYSVRKIEEI RSRLVLASSA VLTVLGSLLM SLGMCFFFGL
360 370 380 390 400
TISLQSKGVY PYLVILVGLE NVLVITKSVL TTDNNLDVKI RVAQGLSREG
410 420 430 440 450
WSITKNLLLE ITILTIGLCT FVPVIQEFCI FAIVGLISDF FLQMMFFSTV
460 470 480 490 500
LALDIKRVEY SAEVRQLPKM LYYNSDRRSE KEGARNGGIS RSMSHPKLSG
510 520 530 540 550
LDQSCGGGHA KKNSLTTCGN GKDKKIPKRL RIVNFWARTR FAQRGFMIWM
560 570 580 590 600
VLWISNIIYN SGLIEFMIDK NMEAQRAARE ASRVDIPVSD MHDLRSADAA
610 620 630 640 650
GHLNLNHFAD GELNSERTPN ITEQLNRLRH PDYETVYQLS NFHWSSILKQ
660 670 680 690 700
YNVSLSGRYV TVLPSIKLSH AVSPQIAQKL RNPDEKAPHH FQWKALAAAL
710 720 730 740 750
DPLDLNDADT GDVPNINTGN APFYPKTPME ILLCCMLIAV SIFMVTYLLV
760 770 780 790 800
MLYRCMCTRN YAEWRASWTA DSENEQEPKQ EQRVLEGVPI QVNGHNHRIE
810 820 830 840 850
CLVTDGNMIA SSCLQGQVKI WDVTNGELMA EIHRNNHFDM QRKEGQRSPT
860 870 880 890 900
GPVLIKGEPS NTNITGMQEI YPEQSPTSFA FKLKKKLQFN FTSPNQSQEP
910 920 930 940 950
KTGKDPSLFD FAAQYEKNFT SDPANSQKRL SNGGLGAELR NRFLSSSGPN
960 970 980 990 1000
PYYEAATVQQ RPNHSEETSQ KPGSSTARKK SYQTSPIWCL DFLDNLIVIG
1010 1020 1030 1040 1050
CADGRLEFWE GTTGNFKGIY ETEHTRNNGV TNIKLTGDKV VAARLSGRID
1060 1070 1080 1090 1100
FLRLETYTQG RQIDWGFTSA YRRTHIRTGS AGSLSMFQQQ PNGPASVHHA
1110 1120 1130 1140 1150
SEEELRCILE FHQQGHQMPV TCLEVAGGTV MTGSMDHTVK VFRLESHQLQ
1160 1170 1180 1190 1200
YTLHGHCGPI SCLFIDQWQA GMGASGCQDG LLCVWDLSRG GCMYKIEAHD
1210 1220 1230 1240 1250
DSIVALACSP SYVISLGLDE RIRVWDRFQG QPLTTMTVSH AYSALVMLTP
1260
SLLVTGKPGL
Length:1,260
Mass (Da):142,563
Last modified:April 8, 2008 - v1
Checksum:i9B803763AED1E07D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232276 Genomic DNA Translation: EDS38944.1
RefSeqiXP_001863686.1, XM_001863651.1
UniGeneiCpi.12091

Genome annotation databases

EnsemblMetazoaiCPIJ013729-RA; CPIJ013729-PA; CPIJ013729
GeneIDi6046500
KEGGicqu:CpipJ_CPIJ013729
VectorBaseiCPIJ013729-RA; CPIJ013729-PA; CPIJ013729

Similar proteinsi

Entry informationi

Entry nameiB0X214_CULQU
AccessioniPrimary (citable) accession number: B0X214
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 12, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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