UniProtKB - B0W943 (B0W943_CULQU)
Protein
Tubulin-specific chaperone A
Gene
6034971
Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Functioni
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.ARBA annotation
GO - Molecular functioni
- beta-tubulin binding Source: InterPro
GO - Biological processi
- post-chaperonin tubulin folding pathway Source: UniProtKB-UniRule
- tubulin complex assembly Source: UniProtKB-UniRule
Keywordsi
Molecular function | ChaperoneUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin-specific chaperone AUniRule annotation |
Gene namesi | Name:6034971Imported ORF Names:CpipJ_CPIJ003559Imported |
Organismi | Culex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported |
Taxonomic identifieri | 7176 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex › |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton UniRule annotation
Cytoskeleton
- microtubule Source: UniProtKB-KW
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotationInteractioni
Subunit structurei
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
UniRule annotationGO - Molecular functioni
- beta-tubulin binding Source: InterPro
Protein-protein interaction databases
STRINGi | 7176.CPIJ003559-PA |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 16 – 43 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 71 – 91 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3470, Eukaryota |
HOGENOMi | CLU_130569_1_1_1 |
InParanoidi | B0W943 |
OMAi | IMMVPDS |
OrthoDBi | 1471374at2759 |
PhylomeDBi | B0W943 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
i Sequence
Sequence statusi: Complete.
B0W943-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDPRLRQLT IKTGVVKRLS KEKTVYEKEV DTQRNRIDKL KAAGSDDYVL
60 70 80 90 100
RKQEEVLQEC MMMVPDCQRR LAKAFEELSE MIKSEEELKE TSQYIAAEAA
LEDAKVNLP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS231862 Genomic DNA Translation: EDS39740.1 |
RefSeqi | XP_001845227.1, XM_001845175.1 |
Genome annotation databases
EnsemblMetazoai | CPIJ003559-RA; CPIJ003559-PA; CPIJ003559 |
GeneIDi | 6034971 |
KEGGi | cqu:CpipJ_CPIJ003559 |
VectorBasei | CPIJ003559-RA; CPIJ003559-PA; CPIJ003559 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS231862 Genomic DNA Translation: EDS39740.1 |
RefSeqi | XP_001845227.1, XM_001845175.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7176.CPIJ003559-PA |
Genome annotation databases
EnsemblMetazoai | CPIJ003559-RA; CPIJ003559-PA; CPIJ003559 |
GeneIDi | 6034971 |
KEGGi | cqu:CpipJ_CPIJ003559 |
VectorBasei | CPIJ003559-RA; CPIJ003559-PA; CPIJ003559 |
Phylogenomic databases
eggNOGi | KOG3470, Eukaryota |
HOGENOMi | CLU_130569_1_1_1 |
InParanoidi | B0W943 |
OMAi | IMMVPDS |
OrthoDBi | 1471374at2759 |
PhylomeDBi | B0W943 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B0W943_CULQU | |
Accessioni | B0W943Primary (citable) accession number: B0W943 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | December 2, 2020 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |