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Entry version 71 (11 Dec 2019)
Sequence version 1 (08 Apr 2008)
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Protein
Submitted name:

Golgi-specific brefeldin a-resistance factor

Gene

6032227

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Golgi-specific brefeldin a-resistance factorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:6032227Imported
ORF Names:CpipJ_CPIJ001197Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7176 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002320 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7176.CPIJ001197-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini643 – 833SEC7InterPro annotationAdd BLAST191

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni244 – 321DisorderedSequence analysisAdd BLAST78
Regioni1245 – 1267DisorderedSequence analysisAdd BLAST23
Regioni1374 – 1406DisorderedSequence analysisAdd BLAST33
Regioni1744 – 1765DisorderedSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0928 Eukaryota
COG5307 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230678

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B0W2G3

KEGG Orthology (KO)

More...
KOi
K18443

Identification of Orthologs from Complete Genome Data

More...
OMAi
DESVCEM

Database of Orthologous Groups

More...
OrthoDBi
815698at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B0W2G3

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00171 Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1000.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
IPR032691 Sec7_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01369 Sec7, 1 hit
PF12783 Sec7_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00222 Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF48425 SSF48425, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50190 SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B0W2G3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPPGNGIFV VRGEMSTLTT AMRRGSRWSS NSYQDDEKDV LLKSFHELKE
60 70 80 90 100
KLLQVEDLRL VEPGLFLNPF LEVIRSEDTT GPVTSLALSA VNKFLSYGLI
110 120 130 140 150
DPTHSTLAAT VESIADAVTH ARFVGTDQTS DGVVLMKIVQ VLRTLVLSPE
160 170 180 190 200
GSALSNESIC DIILSCFRLC FEPRLNELVR KTAENALKDI VLLLFMRLPQ
210 220 230 240 250
FVEGGNFNLK SLKMRSSSMD QSNKKRKSSR AELKPVAVTA PKIVASEEGS
260 270 280 290 300
LEQTEPTTPV VSNAPKGLKP PPLSTTPATP AGPIVDMQGI ISQTPKSSQE
310 320 330 340 350
PKTDPIPEEA DHQQTQPESL QEVPQVAELL EEAPMESFVN AVGVRFTHQQ
360 370 380 390 400
EDETPGPVSH LPYGLPCIRE LFRFLISLCN PHDKQNTDVM IHMGLTLLTV
410 420 430 440 450
TFEVGADSIG KYDSLLAIVK DDLCKNLFAL LATERISIFA ADLQLCFLMF
460 470 480 490 500
ESLRSQLKFQ LEYYLTKLTD LIVNENPRIL YEARELALDN LLQLWRIPGF
510 520 530 540 550
AAELYINYDC DLYCTNLFED LTKLMSKNTL SATHSIYSVH TLSMDSLLTI
560 570 580 590 600
IASIERNCIQ AKNGEKTTYM RHSRNNSSVD KIILDPNISL DQTIVGSPPG
610 620 630 640 650
DQDGDVVVEN INKYLKSSQN EDRLRQLVSQ EGAADGTSLS HEELAAIKKK
660 670 680 690 700
KRLLTQGSDL FNQRPEKGIQ FLQENGILSP VLDPLEVAHF LRENSGLDKK
710 720 730 740 750
MIGEYISKKK NVESKILEVF VKSFDFAGLT IDQALRLYLE TFRLPGEAPL
760 770 780 790 800
IFLVMEHFAD HWHVILHFLE QAEDSVRSET IIKQSCNLHN YNAKRLNVPM
810 820 830 840 850
TVDDFLKNLR GLNGNSDFDQ EMLTNVYNAI KNEEIVMPAE QTGLVRENYL
860 870 880 890 900
WKMLLRRGAT KDGLFHHVFG PNHDRELFRI IQGSTLAALS FIFDRSPENS
910 920 930 940 950
PLYQKATGGF MKSAVIASHY SLHGDFDALV LTLCKFTSLL NPPSDVHEIT
960 970 980 990 1000
ASVLFGQNAK AQLAMKTVFA LIHDHGDCMR EGWKHITDVV LQLFRLKLLP
1010 1020 1030 1040 1050
KALMEAEDFC EPGGKVTLLR EQNLVPKTDA GLLSSLYSYL SNDSQRQPSY
1060 1070 1080 1090 1100
EEQEIIKQSK RCIKECQIEQ IVNESKFLQF ESLVELVNCL LGMIKPPESH
1110 1120 1130 1140 1150
KSVGLPYAEN TVVFLLELLV KVLIQNRDRL LPIWKPCQDQ LYLLLSGSSS
1160 1170 1180 1190 1200
CDYSYLLQRS TVALLKLAIY LMRNEEICST ILQSLRMLLM LKPAVILAIS
1210 1220 1230 1240 1250
KPISIGMYEL LKTSAQNIHS ESDWIIVFTI LECVGAGALP PEYEETPVVS
1260 1270 1280 1290 1300
GTKSDGALSS EEDSGLPDRG YISDSELSAI KSAHSSNSCT PLISPTGDNW
1310 1320 1330 1340 1350
ILVNKDADIV SSRSSSPKHS IQYRCKLLEH SPFALVKCWE SLAFIVRNVA
1360 1370 1380 1390 1400
HITPYNFESC VRCIRTFVEA SMNDGKENRR RQRSGKTSRN RNRKNDASSD
1410 1420 1430 1440 1450
SDSEELPEAY QSISIQLLDL MHTLHTRTAQ IFRWWAEEGG ALPQCSALWS
1460 1470 1480 1490 1500
QGWCPLLQGI ARLATDQRRQ VRTSAITCLQ RALLVQDLQT LTGLEWAGCF
1510 1520 1530 1540 1550
KQVLFPLLSE LLTEKPAKPA DFGLLEESRM RTATIMSKVF LHHLNPLIGL
1560 1570 1580 1590 1600
AGFNELWLEI LDYFERFMKI GSDMLYEAVL ESLKNMLLVM HSVCVFHNSD
1610 1620 1630 1640 1650
GVTHSTLWDV TWQRISGFLP NLKDELFKSD VQTPKVAPVP SPQPPVEPAP
1660 1670 1680 1690 1700
AVNIQPSIIL QPPQGSSEPS ATIRLPTGTS NLLIDNTNLI NPPPVELPQV
1710 1720 1730 1740 1750
APVLIPQAEL ASLPVSPVLQ PVTPQQALSL ENSPTNTNRY SNIIELPVTP
1760 1770 1780 1790 1800
SPPPSEQVQP TETDPQVPLS HLVGGNQYPS LHNVPIGIAQ SFAPIFVQPN
1810 1820 1830 1840 1850
ANPAEGADIY NDYINDPYNL TLQIDSSAQD QQQLPQSAPQ QNVFQSANYF
1860
QFGTGRIPPG SEMLFGEP
Length:1,868
Mass (Da):208,433
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8741CDDBB58BD121
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS231826 Genomic DNA Translation: EDS28709.1

NCBI Reference Sequences

More...
RefSeqi
XP_001842866.1, XM_001842814.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
CPIJ001197-RA; CPIJ001197-PA; CPIJ001197

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6032227

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cqu:CpipJ_CPIJ001197

Bioinformatics Resource for Invertebrate Vectors of Human Pathogens

More...
VectorBasei
CPIJ001197-RA; CPIJ001197-PA; CPIJ001197

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231826 Genomic DNA Translation: EDS28709.1
RefSeqiXP_001842866.1, XM_001842814.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7176.CPIJ001197-PA

Genome annotation databases

EnsemblMetazoaiCPIJ001197-RA; CPIJ001197-PA; CPIJ001197
GeneIDi6032227
KEGGicqu:CpipJ_CPIJ001197
VectorBaseiCPIJ001197-RA; CPIJ001197-PA; CPIJ001197

Phylogenomic databases

eggNOGiKOG0928 Eukaryota
COG5307 LUCA
HOGENOMiHOG000230678
InParanoidiB0W2G3
KOiK18443
OMAiDESVCEM
OrthoDBi815698at2759
PhylomeDBiB0W2G3

Family and domain databases

CDDicd00171 Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
IPR032691 Sec7_N
PfamiView protein in Pfam
PF01369 Sec7, 1 hit
PF12783 Sec7_N, 1 hit
SMARTiView protein in SMART
SM00222 Sec7, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF48425 SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50190 SEC7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB0W2G3_CULQU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B0W2G3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 11, 2019
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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