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Protein

dTDP-4-dehydrorhamnose reductase

Gene

M446_5837

Organism
Methylobacterium sp. (strain 4-46)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.UniRule annotation

Catalytic activityi

dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per monomer.UniRule annotation

Pathwayi: dTDP-L-rhamnose biosynthesis

This protein is involved in the pathway dTDP-L-rhamnose biosynthesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway dTDP-L-rhamnose biosynthesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADPUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00124

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-4-dehydrorhamnose reductaseUniRule annotation (EC:1.1.1.133UniRule annotation)
Gene namesi
Ordered Locus Names:M446_5837Imported
OrganismiMethylobacterium sp. (strain 4-46)Imported
Taxonomic identifieri426117 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000001185 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi426117.M446_5837

Structurei

3D structure databases

ProteinModelPortaliB0UGC7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 290RmlD_sub_bindInterPro annotationAdd BLAST288

Sequence similaritiesi

Belongs to the dTDP-4-dehydrorhamnose reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DBZ Bacteria
COG1091 LUCA
HOGENOMiHOG000227712
KOiK00067
OMAiYHYSNEG
OrthoDBiPOG091H07IL

Family and domain databases

InterProiView protein in InterPro
IPR005913 dTDP_dehydrorham_reduct
IPR036291 NAD(P)-bd_dom_sf
IPR029903 RmlD-like-bd
PANTHERiPTHR10491 PTHR10491, 1 hit
PfamiView protein in Pfam
PF04321 RmlD_sub_bind, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01214 rmlD, 1 hit

Sequencei

Sequence statusi: Complete.

B0UGC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAILILGGG GQVGTALRHA AWPAGVALHA PSREALDVTD EAAVAAALAE
60 70 80 90 100
RAYAAVINAA AYTAVDRAES EVAAAWRLNA LAPAILAAAT ARAGIPLVQV
110 120 130 140 150
STDYVFDGSL AGAYPTDAPV NPASVYGASK AGGEMAVRTA NPRHAVVRTA
160 170 180 190 200
WVVSPHRANF VKTMLRLAGE RDALRVVDDQ RGCPTSADDL AAALAAIALR
210 220 230 240 250
LAEDPAAPGG TYHCVNAGAT TWCGFARAIM AGARARGARA VPVEPIATSS
260 270 280 290
YPTPARRPAN SELSTATLSR DFGIVPRPWE AALADILDRL IGPVTPA
Length:297
Mass (Da):30,452
Last modified:April 8, 2008 - v1
Checksum:iAC1465E955698AF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000943 Genomic DNA Translation: ACA20124.1
RefSeqiWP_012335502.1, NC_010511.1

Genome annotation databases

EnsemblBacteriaiACA20124; ACA20124; M446_5837
KEGGimet:M446_5837

Similar proteinsi

Entry informationi

Entry nameiB0UGC7_METS4
AccessioniPrimary (citable) accession number: B0UGC7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: February 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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