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Protein

60 kDa chaperonin

Gene

groL

Organism
Xylella fastidiosa (strain M12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Xfasm12_1693
OrganismiXylella fastidiosa (strain M12)
Taxonomic identifieri405440 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001300811 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiB0U418

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0U418
SMRiB0U418
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290
KOiK04077
OMAiCVIKVGA

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

B0U418-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEIIFSE KARSRMVYGV NLLANAVKAT LGPKGRNVVL DKNFGSPIIT
60 70 80 90 100
KDGVSVAKEI ELADKFENMG AQMLKEVASK TNDHAGDGTT TATVLAQALI
110 120 130 140 150
REGCKAVAAG MNPMDLKRGI DKAVIAAVTE LKKISKPTSD DKAIAQVATI
160 170 180 190 200
SANSDESIGN IIAEAMKKVG KEGVITIEEG TTLENELDVV EGMQFDRGYS
210 220 230 240 250
SPYFINNQQS QIVELDNPYI LLHDKKISNV RDLLTVLDAV AKESKQLLIV
260 270 280 290 300
AEEVEGEALA TLVVNNIRGI IKVCAVKAPG FGDRRKAMLE DMAVLTGGTV
310 320 330 340 350
ISEEVGLSLE KATTSHLGKA KKVRVSKENT TIIDGMGDND AINGRVKQIK
360 370 380 390 400
TQIEETTSDY DREKLQERVA KLAGGVAVIK VGAATEVEMK EKKARVDDAL
410 420 430 440 450
LATRAAVEEG VIPGGGVALI RVITAISNLK GANEDQTHGI QIALRAMEAP
460 470 480 490 500
LREIVANAGE EPSVILNKVK EGKGNFGYNA ATGEFGDMVN FGILDPTKVT
510 520 530 540
RSALQNAASI AGLMITTEAM IAEAPKKDEP TPPAAGGGMG GMGGMDF
Length:547
Mass (Da):57,881
Last modified:April 8, 2008 - v1
Checksum:i23B211E08E831BA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000941 Genomic DNA Translation: ACA12597.1
RefSeqiWP_004083508.1, NC_010513.1

Genome annotation databases

EnsemblBacteriaiACA12597; ACA12597; Xfasm12_1693
KEGGixfm:Xfasm12_1693

Similar proteinsi

Entry informationi

Entry nameiCH60_XYLFM
AccessioniPrimary (citable) accession number: B0U418
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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