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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Shewanella halifaxensis (strain HAW-EB4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciSHAL458817:G1GB1-464-MONOMER
UniPathwayi
UPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotation (EC:2.4.1.227UniRule annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
Ordered Locus Names:Shal_0455
OrganismiShewanella halifaxensis (strain HAW-EB4)
Taxonomic identifieri458817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001317 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000744701 – 365UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseAdd BLAST365

Proteomic databases

PRIDEiB0TQN7

Interactioni

Protein-protein interaction databases

STRINGi458817.Shal_0455

Structurei

3D structure databases

ProteinModelPortaliB0TQN7
SMRiB0TQN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

B0TQN7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTNQAEEKRI LIMAGGTGGH VFPALAVAKY LSQQGWKVRW LGTAERMEAR
60 70 80 90 100
LVPQHGFDID FIDIKGVRGN GLMRKLAAPF KIIRSVMQAR AVIKKFKPHV
110 120 130 140 150
VMGMGGFASG PGGVAAKLSG IPLVLHEQNA IPGMTNRLLS RIASEVLCAF
160 170 180 190 200
DGTFTDIKAE TVGNPIRKEL IALGEKRKPV CDDDSLKVLV VGGSLGAKIF
210 220 230 240 250
NDVMPSVLEG VSKTHSMTVW HQVGRDNLAT VKAEYQRLGQ DGSVSVAEFI
260 270 280 290 300
DDMEAAYRWA DVVVCRSGAL TVSELAAVGL PSLLVPYPHA VDDHQTKNAK
310 320 330 340 350
VLVNAGAAFL LPQPIVDTSK LMTKLSMLAS DKQELCNMGQ RARDVAILDA
360
TQRVANVCIR LAEKG
Length:365
Mass (Da):39,332
Last modified:April 8, 2008 - v1
Checksum:i65AECC01AD48ABCB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000931 Genomic DNA Translation: ABZ75030.1
RefSeqiWP_012275584.1, NC_010334.1

Genome annotation databases

EnsemblBacteriaiABZ75030; ABZ75030; Shal_0455
KEGGishl:Shal_0455

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000931 Genomic DNA Translation: ABZ75030.1
RefSeqiWP_012275584.1, NC_010334.1

3D structure databases

ProteinModelPortaliB0TQN7
SMRiB0TQN7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi458817.Shal_0455

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Proteomic databases

PRIDEiB0TQN7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ75030; ABZ75030; Shal_0455
KEGGishl:Shal_0455

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Enzyme and pathway databases

UniPathwayi
UPA00219

BioCyciSHAL458817:G1GB1-464-MONOMER

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMURG_SHEHH
AccessioniPrimary (citable) accession number: B0TQN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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