UniProtKB - B0S6I3 (B0S6I3_DANRE)
Protein
Submitted name:
Bone morphogenetic protein/retinoic acid-inducible neural-specific 2
Gene
brinp2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Biological processi
- cell cycle arrest Source: UniProtKB-KW
- cellular response to retinoic acid Source: GO_Central
- negative regulation of mitotic cell cycle Source: GO_Central
- positive regulation of neuron differentiation Source: GO_Central
Keywordsi
Biological process | Cell cycle, Growth arrestARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Bone morphogenetic protein/retinoic acid-inducible neural-specific 2Imported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-070912-621, brinp2 |
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum Source: GO_Central
Other locations
- dendrite Source: GO_Central
- neuronal cell body Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000014302, Expressed in multi-cellular organism and 12 other tissues |
ExpressionAtlasi | B0S6I3, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 88 – 271 | MACPFInterPro annotationAdd BLAST | 184 |
Sequence similaritiesi
Belongs to the BRINP family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000165818 |
HOGENOMi | CLU_018347_0_0_1 |
OMAi | RCSPRFP |
PhylomeDBi | B0S6I3 |
Family and domain databases
InterProi | View protein in InterPro IPR033237, BRINP IPR020864, MACPF |
PANTHERi | PTHR15564, PTHR15564, 1 hit |
Pfami | View protein in Pfam PF19052, BRINP, 1 hit PF01823, MACPF, 1 hit |
SMARTi | View protein in SMART SM00457, MACPF, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
B0S6I3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCWQRAAVVR WFLLMLLWHW APLGPLSWFL ALAERLDQKT SPFSSISGRS
60 70 80 90 100
SGQLDWLLSD KGPFHRCPEY TEFKERFQQG FSTRYKIYRE FSHWKVNSLV
110 120 130 140 150
TEKRDFFKAP LPLAPEFLRN LRLLGRRPSL QQIHENLIKK YGTHFLVSAT
160 170 180 190 200
LGGEESLTIF LDKQKLSKKS EGNGNSSVVS LEILHQLAAS YFTDRESTLR
210 220 230 240 250
RLHHLQIATS AIKVTETRTG PLGCSNYDSL DSVSSVLVHS PENKIHLKGL
260 270 280 290 300
QDVLPEFLRN RFVEAALSYV ACNSEGELLC RNNDCWCRCS TKFPDCNCPF
310 320 330 340 350
ADIKAMEESL RKSKESWINL NQDFIESDEF KAFLKKLPTD HFLNTSAVLK
360 370 380 390 400
FWTSDLVLQR RYGLLEASTK VVLGKAIKIV RKLFALSKRC PTQPKISLPR
410 420 430 440 450
ERTLGFWLNK AQSLLYCSEH GVHGTFSEDL QGCICAAEQR TVCQGTVPCR
460 470 480 490 500
VGEGTLCSSC APDNITRCGT CLPGSILHMG FCRPNIANSL DHYVNFDFDM
510 520 530 540 550
PDAEMRYLLQ RLDSRMEVHA IYISNDVRLG SWFNPAWRKR MLLTLKSNKN
560 570 580 590 600
KSNLIHMLMG ISFQICSTKN STLEPVPAIY VNPFGGSHSE SWFMPVNQQD
610 620 630 640 650
FPDWERTKLD ASLQCYNWTL PLGSKWKSFF ETVHIYLRSR IITDDPTVNE
660 670 680 690 700
TLFYEPLDLD DHSANLGYMK INSLKVFGYS MHFDPEGIKD LILQLDYPYT
710 720 730 740 750
QGSQDAAFLM LLEMRDRINR LSPPGAQPLD LFSCLLRHRL KLSSSEVVRI
760 770
REALQSFNTK LPNSNEPELS QLCS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF1QYG6 | F1QYG6_DANRE | Bone morphogenetic protein/retinoic... | brinp2 fam5b | 776 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX537141 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000133224; ENSDARP00000112914; ENSDARG00000014302 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX537141 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000133224; ENSDARP00000112914; ENSDARG00000014302 |
Organism-specific databases
ZFINi | ZDB-GENE-070912-621, brinp2 |
Phylogenomic databases
GeneTreei | ENSGT00940000165818 |
HOGENOMi | CLU_018347_0_0_1 |
OMAi | RCSPRFP |
PhylomeDBi | B0S6I3 |
Gene expression databases
Bgeei | ENSDARG00000014302, Expressed in multi-cellular organism and 12 other tissues |
ExpressionAtlasi | B0S6I3, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR033237, BRINP IPR020864, MACPF |
PANTHERi | PTHR15564, PTHR15564, 1 hit |
Pfami | View protein in Pfam PF19052, BRINP, 1 hit PF01823, MACPF, 1 hit |
SMARTi | View protein in SMART SM00457, MACPF, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B0S6I3_DANRE | |
Accessioni | B0S6I3Primary (citable) accession number: B0S6I3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | April 7, 2021 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |