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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:OE_4165R
OrganismiHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Taxonomic identifieri478009 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000001321 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001158141 – 247DNA polymerase sliding clampAdd BLAST247

Proteomic databases

PRIDEiB0R7F7

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0R7F7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000222371
KOiK04802
OMAiINTQKEH
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

B0R7F7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFKAIVSADT LQETLDSVSV LVDECKIHLD DDTLSIRAVD PASVGMVDLD
60 70 80 90 100
LAATAFESYE ADGGLIGVNL SRLEDIAGMA DAGQLIQLEL DEETRKLHIQ
110 120 130 140 150
IDGLEYTLAL IDPDSIRQEP DIPDLDLPAH VAIEGRDIDR AVTAADMVSD
160 170 180 190 200
HIALGVDTGD DLFYVNAEGD TDDVHLELAP DQLIDLDAGD AHSLFSLDYL
210 220 230 240
KDMNKAIPTT AEVELELGDE FPIKLHFDIA DAQGHVTYML APRIQSN
Length:247
Mass (Da):26,824
Last modified:April 8, 2008 - v1
Checksum:iB1506BBD54851544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM774415 Genomic DNA Translation: CAP14676.1
RefSeqiWP_010903677.1, NC_010364.1

Genome annotation databases

EnsemblBacteriaiCAP14676; CAP14676; OE_4165R
GeneIDi5953309
KEGGihsl:OE_4165R

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM774415 Genomic DNA Translation: CAP14676.1
RefSeqiWP_010903677.1, NC_010364.1

3D structure databases

ProteinModelPortaliB0R7F7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB0R7F7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP14676; CAP14676; OE_4165R
GeneIDi5953309
KEGGihsl:OE_4165R

Phylogenomic databases

HOGENOMiHOG000222371
KOiK04802
OMAiINTQKEH
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPCNA_HALS3
AccessioniPrimary (citable) accession number: B0R7F7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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