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Entry version 70 (07 Oct 2020)
Sequence version 1 (08 Apr 2008)
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Protein

Sensory rhodopsin I transducer

Gene

htr1

Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transduces signals from the phototaxis receptor sensory rhodopsin I (SR-I) to the flagellar motor. Responds to light changes through the variation of the level of methylation.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPhotoreceptor protein, Receptor, Transducer
Biological processSensory transduction
LigandChromophore

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sensory rhodopsin I transducer
Alternative name(s):
HTR-I
Methyl-accepting phototaxis protein I
Short name:
MPP-I
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:htr1
Synonyms:htr, htrI
Ordered Locus Names:OE_3347F
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri478009 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001321 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini2 – 14CytoplasmicSequence analysisAdd BLAST13
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei15 – 29HelicalSequence analysisAdd BLAST15
Topological domaini30 – 39ExtracellularSequence analysis10
Transmembranei40 – 55HelicalSequence analysisAdd BLAST16
Topological domaini56 – 536CytoplasmicSequence analysisAdd BLAST481

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004290752 – 536Sensory rhodopsin I transducerAdd BLAST535

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei266Glutamate methyl ester (Glu)By similarity1
Modified residuei473Glutamate methyl ester (Glu)By similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Methylated by CheR.1 Publication

Keywords - PTMi

Methylation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B0R632

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini55 – 107HAMP 1PROSITE-ProRule annotationAdd BLAST53
Domaini149 – 202HAMP 2PROSITE-ProRule annotationAdd BLAST54
Domaini221 – 459Methyl-accepting transducerPROSITE-ProRule annotationAdd BLAST239

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000445_107_18_2

KEGG Orthology (KO)

More...
KOi
K03406

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPPVGTD

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06225, HAMP, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004090, Chemotax_Me-accpt_rcpt
IPR003660, HAMP_dom
IPR004089, MCPsignal_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00672, HAMP, 2 hits
PF00015, MCPsignal, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00260, CHEMTRNSDUCR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00304, HAMP, 3 hits
SM00283, MA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50111, CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885, HAMP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

B0R632-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIAWARRRY GVKLGLGYIA TAGLLVGVGV TTNDVPSTIV AGIAGLLTLG
60 70 80 90 100
SINAAETVAS IKEIAAQTER VANGNLEQEV TSTRTDEFGS LADSIEQMRQ
110 120 130 140 150
SLRGRLNEME RTRADLEETQ AEAETAREEA EQAKQEAQAA EREARELAAT
160 170 180 190 200
YQDTAKRYGE TMEAAATGDL TQRVDVDTDH EAMETVGTAF NQMMDDLQAT
210 220 230 240 250
VRTVTTVADE IEAKTERMSE TSADIEASAG DTVEAVSKIE SQANDQRTEL
260 270 280 290 300
DSAADDVQQV SASAEEIAAT IDDLASRSED VATASDAARD SSKSALDEMS
310 320 330 340 350
SIETEVDDAV GQVEQLRDQV AEITDIVDVI TDIGEQTNML ALNASIEAAR
360 370 380 390 400
AGGNADGDGF SVVADEVKDL AEETQDRANE IAAVVEKVTA QTEDVTASIQ
410 420 430 440 450
QTRTRVESGS ETVESTLRDI RTIADSIAEV SNSIDEIQRT TSEQAETVQS
460 470 480 490 500
TATSVERVAG LSDDTTALAS DAESAVIGQR ESAEEIAASL EQFQNTAVEQ
510 520 530
LQSRVASFTV ATEDSETAGG SVEQPVMRAG ADGGGA
Length:536
Mass (Da):56,675
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i24B6413266A9D085
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti34D → E in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti55A → G in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti59 – 60AS → GR in CAA48578 (PubMed:8344242).Curated2
Sequence conflicti65A → G in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti114A → S in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti121 – 126AEAETA → TESETT in CAA48578 (PubMed:8344242).Curated6
Sequence conflicti130A → S in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti139A → S in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti154 – 158TAKRY → SSNRD in CAA48578 (PubMed:8344242).Curated5
Sequence conflicti164 – 165AA → SS in CAA48578 (PubMed:8344242).Curated2
Sequence conflicti170L → F in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti180H → P in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti186V → F in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti243A → P in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti309A → P in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti315Q → H in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti401Q → H in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti418 – 419RD → LH in CAA48578 (PubMed:8344242).Curated2
Sequence conflicti428A → S in CAA48578 (PubMed:8344242).Curated1
Sequence conflicti475A → P in CAA48578 (PubMed:8344242).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X68591 Genomic DNA Translation: CAA48578.1
AM774415 Genomic DNA Translation: CAP14201.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A47190

NCBI Reference Sequences

More...
RefSeqi
WP_010903210.1, NC_010364.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAP14201; CAP14201; OE_3347F

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5953066

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsl:OE_3347F

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68591 Genomic DNA Translation: CAA48578.1
AM774415 Genomic DNA Translation: CAP14201.1
PIRiA47190
RefSeqiWP_010903210.1, NC_010364.1

3D structure databases

SMRiB0R632
ModBaseiSearch...

Genome annotation databases

EnsemblBacteriaiCAP14201; CAP14201; OE_3347F
GeneIDi5953066
KEGGihsl:OE_3347F

Phylogenomic databases

HOGENOMiCLU_000445_107_18_2
KOiK03406
OMAiKPPVGTD

Family and domain databases

CDDicd06225, HAMP, 2 hits
InterProiView protein in InterPro
IPR004090, Chemotax_Me-accpt_rcpt
IPR003660, HAMP_dom
IPR004089, MCPsignal_dom
PfamiView protein in Pfam
PF00672, HAMP, 2 hits
PF00015, MCPsignal, 1 hit
PRINTSiPR00260, CHEMTRNSDUCR
SMARTiView protein in SMART
SM00304, HAMP, 3 hits
SM00283, MA, 1 hit
PROSITEiView protein in PROSITE
PS50111, CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885, HAMP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHTR1_HALS3
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B0R632
Secondary accession number(s): P33741, P33955, Q9HPF6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: April 8, 2008
Last modified: October 7, 2020
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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