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UniProtKB - B0R142 (B0R142_DANRE)

Entry version 105 (07 Apr 2021)
Sequence version 1 (08 Apr 2008)
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Protein
Submitted name:

Taste receptor, type 1, member 2, tandem duplicate 2

Gene

tas1r2.1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptorARBA annotation, Receptor, Transducer

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DRE-418594, G alpha (i) signalling events
R-DRE-420499, Class C/3 (Metabotropic glutamate/pheromone receptors)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Taste receptor, type 1, member 2, tandem duplicate 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tas1r2.1Imported
Synonyms:tas1r2.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-070917-1, tas1r2.1
ZDB-GENE-070917-2, tas1r2.2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSDARG00000059397, Expressed in female gonad and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7955.ENSDARP00000069610

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini550 – 815G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST266

Keywords - Domaini

Transmembrane, Transmembrane helixARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1056, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156136

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_005389_5_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		B0R142

Identification of Orthologs from Complete Genome Data

More...OMAi		GYEMFDH

TreeFam database of animal gene trees

More...TreeFami		TF331269

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.10.50.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001828, ANF_lig-bd_rcpt
IPR000337, GPCR_3
IPR011500, GPCR_3_9-Cys_dom
IPR038550, GPCR_3_9-Cys_sf
IPR017978, GPCR_3_C
IPR000068, GPCR_3_Ca_sens_rcpt-rel
IPR017979, GPCR_3_CS
IPR028082, Peripla_BP_I

The PANTHER Classification System

More...PANTHERi		PTHR24061, PTHR24061, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00003, 7tm_3, 1 hit
PF01094, ANF_receptor, 1 hit
PF07562, NCD3G, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00248, GPCRMGR

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53822, SSF53822, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00980, G_PROTEIN_RECEP_F3_2, 1 hit
PS00981, G_PROTEIN_RECEP_F3_3, 1 hit
PS50259, G_PROTEIN_RECEP_F3_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B0R142-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLDSNYIFL LGFINSLFFN FCSLASDFSL EGDFLLGGLF PLHEIDQVTP 
        60         70         80         90        100
VFTPETTECF RYTASPSGFQ MLQVMRFAVE EINNSSTLLP NVSLGYELFD 
       110        120        130        140        150
HCSNTRNFGS LLSFISKNGS IKPKVKRINY QSDVIALTGP YGSTRTISIA 
       160        170        180        190        200
PLITMDLIPL VNYGASSSVL SNKLQYPSFV RTVPSNKDMI NMIIHMIRWF 
       210        220        230        240        250
GWNWVAFLGS KDAYSTDGLN LFNTYINNTG ICVAYQERLN LDANYSQTLK 
       260        270        280        290        300
KIDMLNINVI VVFAVPQYAV NIINTAIADN IRDKVWIASE TWSMNQQLPR 
       310        320        330        340        350
EPGVEKIGTV IGITDRLLTL PGFNEFILKD MGTANVNASK FQTNTCNQNC 
       360        370        380        390        400
DYCPSLTAED IINENPSFSF AIYAAMYTIA HALHKVLQCD TKGCPKNTPF 
       410        420        430        440        450
EPYMLLGEMK KLDFPLNGRQ VKYDKNYDPP ISYAVVLWHT DENSPQFEMV 
       460        470        480        490        500
GTYDTYPKTV FTIDNSRFPW RNDSIPFSNC SVECKPGFAR QPEGFHSCCF 
       510        520        530        540        550
TCKKCPRNSY VDYSQDPYTC FPCAVSDWSD EGSTACKTRA VVYLEFTEIT 
       560        570        580        590        600
SIAVMISVSF LIILLIGIFG LFAYNFNTPV VRSAGGGMCL LMLLCLTISS 
       610        620        630        640        650
ISVFFFFGKP SSVHCLVRNA IFAFFFTVCL SCLTVRSFQI ICVFKMAAQF 
       660        670        680        690        700
PRLHSLWVKH NGQWLFIAFS SFIHLISCVI WTTVSPDIPI ADSWTFKDQT 
       710        720        730        740        750
LLMCEMVNTI TFTVVLFISW FLGFLCLVFS YMGRDLPKNY NEAKSITFSL 
       760        770        780        790        800
ILYYLSWIVY FTAYLSIKSK YIMLLNAMAQ ISSIYGILFS YFIPKSYIMI 
       810        820 
FQPQKNTAAY FQTSIQNYTQ TISRS
Length:825
Mass (Da):93,503
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i25E331F6A7418DEF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1QRP7F1QRP7_DANRE
Taste receptor, type 1, member 2, t...
tas1r2.2
824Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL935148 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		XP_009302534.1, XM_009304259.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSDART00000075125; ENSDARP00000069610; ENSDARG00000053135

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935148 Genomic DNA No translation available.
RefSeqiXP_009302534.1, XM_009304259.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000069610

Genome annotation databases

EnsembliENSDART00000075125; ENSDARP00000069610; ENSDARG00000053135

Organism-specific databases

ZFINiZDB-GENE-070917-1, tas1r2.1
ZDB-GENE-070917-2, tas1r2.2

Phylogenomic databases

eggNOGiKOG1056, Eukaryota
GeneTreeiENSGT00940000156136
HOGENOMiCLU_005389_5_1_1
InParanoidiB0R142
OMAiGYEMFDH
TreeFamiTF331269

Enzyme and pathway databases

ReactomeiR-DRE-418594, G alpha (i) signalling events
R-DRE-420499, Class C/3 (Metabotropic glutamate/pheromone receptors)

Gene expression databases

BgeeiENSDARG00000059397, Expressed in female gonad and 4 other tissues

Family and domain databases

Gene3Di2.10.50.30, 1 hit
InterProiView protein in InterPro
IPR001828, ANF_lig-bd_rcpt
IPR000337, GPCR_3
IPR011500, GPCR_3_9-Cys_dom
IPR038550, GPCR_3_9-Cys_sf
IPR017978, GPCR_3_C
IPR000068, GPCR_3_Ca_sens_rcpt-rel
IPR017979, GPCR_3_CS
IPR028082, Peripla_BP_I
PANTHERiPTHR24061, PTHR24061, 1 hit
PfamiView protein in Pfam
PF00003, 7tm_3, 1 hit
PF01094, ANF_receptor, 1 hit
PF07562, NCD3G, 1 hit
PRINTSiPR00248, GPCRMGR
SUPFAMiSSF53822, SSF53822, 1 hit
PROSITEiView protein in PROSITE
PS00980, G_PROTEIN_RECEP_F3_2, 1 hit
PS00981, G_PROTEIN_RECEP_F3_3, 1 hit
PS50259, G_PROTEIN_RECEP_F3_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB0R142_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B0R142
Secondary accession number(s): X1WC23
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 7, 2021
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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