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Protein
Submitted name:

Chromodomain helicase DNA-binding protein 3

Gene

Chd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • centrosome cycle Source: MGI
  • chromatin assembly or disassembly Source: MGI
  • spindle organization Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-3214815 HDACs deacetylate histones
R-MMU-6804758 Regulation of TP53 Activity through Acetylation
R-MMU-73762 RNA Polymerase I Transcription Initiation
R-MMU-8943724 Regulation of PTEN gene transcription

Names & Taxonomyi

Protein namesi
Submitted name:
Chromodomain helicase DNA-binding protein 3Imported
Gene namesi
Name:Chd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1344395 Chd3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiB0QZH7
PeptideAtlasiB0QZH7
PRIDEiB0QZH7

Expressioni

Gene expression databases

BgeeiENSMUSG00000018474 Expressed in 241 organ(s), highest expression level in manus
ExpressionAtlasiB0QZH7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB0QZH7
SMRiB0QZH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 131PHD-typeInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili130 – 150Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0383 Eukaryota
COG0553 LUCA
GeneTreeiENSGT00760000119067

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028722 CHD3
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10799:SF544 PTHR10799:SF544, 1 hit
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

B0QZH7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LKIKLGLLGG KRKKAGSSEE GHEPEAEESD LDSGSVHSAS GWPDGPVRAK
60 70 80 90 100
KLKRGRPGRK KKKVLGCPAV TGEEEVDGYE TDHQDYCEVC QQGGEIILCD
110 120 130 140 150
TCPRAYHLVC LDPELDRAPE GKWSCPHCEK EGVQWEAKEE EEEYEEEGEE

G
Length:151
Mass (Da):16,694
Last modified:March 3, 2009 - v2
Checksum:i0754958440DEBA4C
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AR17B1AR17_MOUSE
Chromodomain helicase DNA-binding p...
Chd3
2,055Annotation score:
E9Q614E9Q614_MOUSE
Chromodomain helicase DNA-binding p...
Chd3
2,021Annotation score:
F7C528F7C528_MOUSE
Chromodomain helicase DNA-binding p...
Chd3
1,886Annotation score:
B0QZH8B0QZH8_MOUSE
Chromodomain helicase DNA-binding p...
Chd3
143Annotation score:
F6V4V3F6V4V3_MOUSE
Chromodomain helicase DNA-binding p...
Chd3
197Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei151Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596125 Genomic DNA No translation available.
AL645527 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000154046; ENSMUSP00000121192; ENSMUSG00000018474

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596125 Genomic DNA No translation available.
AL645527 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB0QZH7
SMRiB0QZH7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB0QZH7
PeptideAtlasiB0QZH7
PRIDEiB0QZH7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000154046; ENSMUSP00000121192; ENSMUSG00000018474

Organism-specific databases

MGIiMGI:1344395 Chd3

Phylogenomic databases

eggNOGiKOG0383 Eukaryota
COG0553 LUCA
GeneTreeiENSGT00760000119067

Enzyme and pathway databases

ReactomeiR-MMU-3214815 HDACs deacetylate histones
R-MMU-6804758 Regulation of TP53 Activity through Acetylation
R-MMU-73762 RNA Polymerase I Transcription Initiation
R-MMU-8943724 Regulation of PTEN gene transcription

Miscellaneous databases

ChiTaRSiChd3 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018474 Expressed in 241 organ(s), highest expression level in manus
ExpressionAtlasiB0QZH7 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028722 CHD3
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10799:SF544 PTHR10799:SF544, 1 hit
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0QZH7_MOUSE
AccessioniPrimary (citable) accession number: B0QZH7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: March 3, 2009
Last modified: November 7, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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