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Protein
Submitted name:

RNA-binding protein fox-1 homolog 2

Gene

RBFOX2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
RNA-binding protein fox-1 homolog 2Imported
Gene namesi
Name:RBFOX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000100320.22
HGNCiHGNC:9906 RBFOX2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100320

PTM / Processingi

Proteomic databases

MaxQBiB0QYY6
PeptideAtlasiB0QYY6
PRIDEiB0QYY6

Expressioni

Gene expression databases

BgeeiENSG00000100320 Expressed in 240 organ(s), highest expression level in frontal cortex
ExpressionAtlasiB0QYY6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 128RRMInterPro annotationAdd BLAST38

Phylogenomic databases

eggNOGiKOG0125 Eukaryota
ENOG4111WJT LUCA
GeneTreeiENSGT00390000013767
HOVERGENiHBG061775

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

B0QYY6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVQPFTTIPF PPPPQNGIPT EYGVPHTQDY AGQTGEHNLT LYGSTQAHGE
60 70 80 90 100
QSSNSPSTQN GSLTTEGGAQ TDGQQSQTQS SENSESKSTP KRLHVSNIPF
110 120
RFRDPDLRQM FGFGKILDVE IIFNERGS
Length:128
Mass (Da):13,995
Last modified:March 3, 2009 - v1
Checksum:i708B4EE48B79DFD5
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43251RFOX2_HUMAN
RNA binding protein fox-1 homolog 2
RBFOX2 FOX2, HRNBP2, RBM9, RTA
390Annotation score:
B0QYY4B0QYY4_HUMAN
RNA binding protein fox-1 homolog
RBFOX2
370Annotation score:
B0QYV1B0QYV1_HUMAN
RNA binding protein fox-1 homolog
RBFOX2
357Annotation score:
B0QYY7B0QYY7_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
200Annotation score:
S4R469S4R469_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
234Annotation score:
A0A0G2JRA5A0A0G2JRA5_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
389Annotation score:
S4R3K7S4R3K7_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
230Annotation score:
A0A0G2JSB3A0A0G2JSB3_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
186Annotation score:
A0A0G2JRD1A0A0G2JRD1_HUMAN
RNA-binding protein fox-1 homolog 2
RBFOX2
227Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei128Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC239364 Genomic DNA No translation available.
AL049748 Genomic DNA No translation available.
AL079295 Genomic DNA No translation available.
KF457428 Genomic DNA No translation available.
KF510602 Genomic DNA No translation available.
KF510603 Genomic DNA No translation available.
KF511452 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000397305; ENSP00000380472; ENSG00000100320
ENST00000629809; ENSP00000486659; ENSG00000277564
UCSCiuc062drr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC239364 Genomic DNA No translation available.
AL049748 Genomic DNA No translation available.
AL079295 Genomic DNA No translation available.
KF457428 Genomic DNA No translation available.
KF510602 Genomic DNA No translation available.
KF510603 Genomic DNA No translation available.
KF511452 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB0QYY6
PeptideAtlasiB0QYY6
PRIDEiB0QYY6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000397305; ENSP00000380472; ENSG00000100320
ENST00000629809; ENSP00000486659; ENSG00000277564
UCSCiuc062drr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000100320.22
HGNCiHGNC:9906 RBFOX2
OpenTargetsiENSG00000100320
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0125 Eukaryota
ENOG4111WJT LUCA
GeneTreeiENSGT00390000013767
HOVERGENiHBG061775

Miscellaneous databases

ChiTaRSiRBFOX2 human

Gene expression databases

BgeeiENSG00000100320 Expressed in 240 organ(s), highest expression level in frontal cortex
ExpressionAtlasiB0QYY6 baseline and differential

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0QYY6_HUMAN
AccessioniPrimary (citable) accession number: B0QYY6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 12, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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