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Protein
Submitted name:

Interleukin-2 receptor subunit beta

Gene

IL2RB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-2 receptor subunit betaImported
Gene namesi
Name:IL2RBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000100385.13
HGNCiHGNC:6009 IL2RB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100385

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500275181527 – 188Sequence analysisAdd BLAST162

Proteomic databases

PeptideAtlasiB0QYC0

Expressioni

Gene expression databases

BgeeiENSG00000100385 Expressed in 153 organ(s), highest expression level in mononuclear cell
ExpressionAtlasiB0QYC0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB0QYC0
SMRiB0QYC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410II5H Eukaryota
ENOG410YXT9 LUCA
GeneTreeiENSGT00510000049239

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036116 FN3_sf
IPR013783 Ig-like_fold
SUPFAMiSSF49265 SSF49265, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

B0QYC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPALSWRL PLLILLLPLA TSWASAAVNG TSQFTCFYNS RANISCVWSQ
60 70 80 90 100
DGALQDTSCQ VHAWPDRRRW NQTCELLPVS QASWACNLIL GAPDSQKLTT
110 120 130 140 150
VDIVTLRVLC REGVRWRVMA IQDFKPFENL RLMAPISLQV VHVETHRCNI
160 170 180
SWEISQASHY FERHLEFEAR TLSPGHTWEE APLLTLKQ
Length:188
Mass (Da):21,400
Last modified:April 8, 2008 - v1
Checksum:i688F5A441F81D5CE
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P14784IL2RB_HUMAN
Interleukin-2 receptor subunit beta
IL2RB IL15RB
551Annotation score:
B0QYC2B0QYC2_HUMAN
Interleukin-2 receptor subunit beta
IL2RB
88Annotation score:
B0QYC1B0QYC1_HUMAN
Interleukin-2 receptor subunit beta
IL2RB
146Annotation score:
H7C1H9H7C1H9_HUMAN
Interleukin-2 receptor subunit beta
IL2RB
105Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei188Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022314 Genomic DNA No translation available.
KF457432 Genomic DNA No translation available.
KF457436 Genomic DNA No translation available.
Z82188 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000453962; ENSP00000403731; ENSG00000100385
UCSCiuc062dwh.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022314 Genomic DNA No translation available.
KF457432 Genomic DNA No translation available.
KF457436 Genomic DNA No translation available.
Z82188 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB0QYC0
SMRiB0QYC0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB0QYC0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000453962; ENSP00000403731; ENSG00000100385
UCSCiuc062dwh.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000100385.13
HGNCiHGNC:6009 IL2RB
OpenTargetsiENSG00000100385
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410II5H Eukaryota
ENOG410YXT9 LUCA
GeneTreeiENSGT00510000049239

Gene expression databases

BgeeiENSG00000100385 Expressed in 153 organ(s), highest expression level in mononuclear cell
ExpressionAtlasiB0QYC0 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036116 FN3_sf
IPR013783 Ig-like_fold
SUPFAMiSSF49265 SSF49265, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0QYC0_HUMAN
AccessioniPrimary (citable) accession number: B0QYC0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 12, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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