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Protein

Choline transporter-like protein 5

Gene

slc44a5

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Choline transporter-like protein 5
Alternative name(s):
Solute carrier family 44 member 5
Gene namesi
Name:slc44a5
Synonyms:ctl5
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-987953 slc44a5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 33CytoplasmicSequence analysisAdd BLAST33
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Topological domaini55 – 237ExtracellularSequence analysisAdd BLAST183
Transmembranei238 – 258HelicalSequence analysisAdd BLAST21
Topological domaini259 – 261CytoplasmicSequence analysis3
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Topological domaini283 – 320ExtracellularSequence analysisAdd BLAST38
Transmembranei321 – 341HelicalSequence analysisAdd BLAST21
Topological domaini342 – 346CytoplasmicSequence analysis5
Transmembranei347 – 367HelicalSequence analysisAdd BLAST21
Topological domaini368 – 369ExtracellularSequence analysis2
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Topological domaini391 – 455CytoplasmicSequence analysisAdd BLAST65
Transmembranei456 – 476HelicalSequence analysisAdd BLAST21
Topological domaini477 – 510ExtracellularSequence analysisAdd BLAST34
Transmembranei511 – 531HelicalSequence analysisAdd BLAST21
Topological domaini532 – 605CytoplasmicSequence analysisAdd BLAST74
Transmembranei606 – 626HelicalSequence analysisAdd BLAST21
Topological domaini627 – 644ExtracellularSequence analysisAdd BLAST18
Transmembranei645 – 665HelicalSequence analysisAdd BLAST21
Topological domaini666 – 711CytoplasmicSequence analysisAdd BLAST46

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003597261 – 714Choline transporter-like protein 5Add BLAST714

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi132N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi192N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi205N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiB0JZD0

Structurei

3D structure databases

SMRiB0JZD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG062155
InParanoidiB0JZD0
KOiK15377

Family and domain databases

InterProiView protein in InterPro
IPR007603 Choline_transptr-like
PANTHERiPTHR12385 PTHR12385, 1 hit
PfamiView protein in Pfam
PF04515 Choline_transpo, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B0JZD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRRSAAPTS PFGEPRKFDP KFKGPIGKRH CTDVLCCIIF VVVILGYIAL
60 70 80 90 100
GVVAWIHGDP RKIIYPTDSY GQFCGQKGTP NENKTILMYF NILRCASPVV
110 120 130 140 150
LINLQCPTTQ LCVSKCPDRF ATYLDMQANR FNNSYWEYYK QFCKPGFDKP
160 170 180 190 200
RKSITEVLRD EDCPSMIIPS RPFLQRCFPD FSTRNGVLTV ANKTEFKDGI
210 220 230 240 250
GQMRNVTDLR SAANGINNVL DARSVGMKIF EDYASSWYWI LIALFIAMVV
260 270 280 290 300
SLLFLILLRF TAGVFFWIFI IGVIGVVGYG IWHCFWEYDS LKGVPGADLT
310 320 330 340 350
IYDIGLQTDF RVYLQLRQTW LAFMILLCIV EVIIILMLIF LRNRIRIAIA
360 370 380 390 400
LLQEGSRAIG YIMSTLFYPI ITFILIAICI SYWAVTAVFM ATSGEPIYKV
410 420 430 440 450
MANKTLCKYA DITCIPETFN TTNVTRLCPG AQCTFAFYGG ESFYHQYILI
460 470 480 490 500
FQLCNVFVFL WLVNFSIALG QCTLAGAFAS YYWAFKKPAD IPACPLFSSF
510 520 530 540 550
GRAIRYHTGS LALGSLILAL VQFIRIILEY LDHKLKASQN SFAKFILCCL
560 570 580 590 600
KCCFWCLEKF IKFMNRNAYI MIAIYGKNFC TSAKDAFFLL MRNVIRVAVL
610 620 630 640 650
DKVTDFLLFL GKVFVTGSVG VLAFFFFTRK IPVLTDEAPA LNYYWVPLLT
660 670 680 690 700
VLIGSYLIAH GFFSVYAMCV DTLFLCFCED LERNNGSSSK PYYMSPNLHR
710
ILGKKEILSK KAKR
Length:714
Mass (Da):81,265
Last modified:March 18, 2008 - v1
Checksum:i22BBAF7DB25DE9F5
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7EQK6F7EQK6_XENTR
Choline transporter-like protein 5
slc44a5
701Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC159131 mRNA Translation: AAI59132.1
RefSeqiNP_001120142.1, NM_001126670.1
UniGeneiStr.21145

Genome annotation databases

GeneIDi100145179
KEGGixtr:100145179

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC159131 mRNA Translation: AAI59132.1
RefSeqiNP_001120142.1, NM_001126670.1
UniGeneiStr.21145

3D structure databases

SMRiB0JZD0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB0JZD0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100145179
KEGGixtr:100145179

Organism-specific databases

CTDi204962
XenbaseiXB-GENE-987953 slc44a5

Phylogenomic databases

HOVERGENiHBG062155
InParanoidiB0JZD0
KOiK15377

Family and domain databases

InterProiView protein in InterPro
IPR007603 Choline_transptr-like
PANTHERiPTHR12385 PTHR12385, 1 hit
PfamiView protein in Pfam
PF04515 Choline_transpo, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCTL5_XENTR
AccessioniPrimary (citable) accession number: B0JZD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: March 18, 2008
Last modified: May 10, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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