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Protein
Submitted name:

Cytochrome P450, family 4, subfamily a, polypeptide 12B

Gene

Cyp4a12b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 4, subfamily a, polypeptide 12BImported
Gene namesi
Name:Cyp4a12bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:3611747 Cyp4a12b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

ProteinModelPortaliB0G0Y2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
HOVERGENiHBG000182
KOiK07425

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

B0G0Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSASALSSIR FPGSISEYLQ VASVLSLLLL LFKTAQLYLH RQWLLSSTQQ
60 70 80 90 100
FPSPPSHWLF GHKILKDQDL QDILTRIKNF PSACPQWLWG SKVRIQVYDP
110 120 130 140 150
DYMKLILGRS DPKAHGSYRF LAPWIGRGLL LLDGQTWFQH RRMLTPAFHY
160 170 180 190 200
DILKPYTEIM ADSVHVMLDK WEQIVGQDST LEIFQHITLM TLDTIMKCAF
210 220 230 240 250
SHEGSVQLDR KYKSYIQAVE DLNNLFFLRV RNIFHQNDII YRVSSNGCLA
260 270 280 290 300
NSACQLAHDH TDQVIKSRRS QLQDEEELEK LKMKRRLDFL DILLFARMEN
310 320 330 340 350
GKSLSDKDLR AEVDTFMFEG HDTTASSISW IFYALATNPE HQQRCRKEIQ
360 370 380 390 400
SLLGDGASIT WNDLDKMPYT TMCIKEALRI YPPVPSVSRE LSSPVTFPDG
410 420 430 440 450
RSLPKGIHVM LSFYGLHHNP TVWPNPEVFD PSRFAPGSSR HSHSFLPFSG
460 470 480 490 500
GARNCIGKQF AMNELKVAVA LTLLRFELLP DPTRVPIPIP RIVLKSKNGI

HLHLKKLQ
Length:508
Mass (Da):58,342
Last modified:February 26, 2008 - v1
Checksum:i3C05B1D5FD7EBE55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060945 mRNA Translation: AAH60945.1
RefSeqiNP_758510.2, NM_172306.2
UniGeneiMm.448292

Genome annotation databases

GeneIDi13118
KEGGimmu:13118

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060945 mRNA Translation: AAH60945.1
RefSeqiNP_758510.2, NM_172306.2
UniGeneiMm.448292

3D structure databases

ProteinModelPortaliB0G0Y2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13118
KEGGimmu:13118

Organism-specific databases

CTDi13118
MGIiMGI:3611747 Cyp4a12b

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
HOVERGENiHBG000182
KOiK07425

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0G0Y2_MOUSE
AccessioniPrimary (citable) accession number: B0G0Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 20, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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