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Protein

Nuclear receptor coactivator

Gene

SRC3

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorUniRule annotation, ReceptorImported
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear receptor coactivatorUniRule annotation
Gene namesi
Name:SRC3Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiB0FRD8

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB0FRD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 84BHLHInterPro annotationAdd BLAST58
Domaini101 – 164PASInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the SRC/p160 nuclear receptor coactivator family.UniRule annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQ5R Eukaryota
ENOG410ZDZC LUCA
HOVERGENiHBG052583
KOiK11256

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00130 PAS, 1 hit
Gene3Di1.10.287.1070, 1 hit
4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR010011 DUF1518
IPR032565 DUF4927
IPR036638 HLH_DNA-bd_sf
IPR028818 NCOA3
IPR009110 Nuc_rcpt_coact
IPR014920 Nuc_rcpt_coact_Ncoa-typ
IPR037077 Nuc_rcpt_coact_Ncoa_int_sf
IPR017426 Nuclear_rcpt_coactivator
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013767 PAS_fold
IPR014935 SRC/p160_LXXLL
PANTHERiPTHR10684 PTHR10684, 1 hit
PTHR10684:SF3 PTHR10684:SF3, 1 hit
PfamiView protein in Pfam
PF07469 DUF1518, 1 hit
PF16279 DUF4927, 1 hit
PF08815 Nuc_rec_co-act, 1 hit
PF00989 PAS, 1 hit
PF08832 SRC-1, 1 hit
PIRSFiPIRSF038181 Nuclear_receptor_coactivator, 1 hit
SMARTiView protein in SMART
SM01151 DUF1518, 1 hit
SM00353 HLH, 1 hit
SM00091 PAS, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
SSF55785 SSF55785, 2 hits
SSF69125 SSF69125, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS50112 PAS, 1 hit

Sequencei

Sequence statusi: Complete.

B0FRD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSGLGENSL DPLAPDSRKR KLPCDTPGQG LTCSGEKWRR EQESKYIEEL
60 70 80 90 100
AELISANLSD IDNFNVKPDK CAILKETVRQ IRQIKEQGQG VIDKDSLGPL
110 120 130 140 150
LLQALDGFLF VVNREGNIVF VSENVTQYLQ YKQEDLVNTS VYSILHEEDR
160 170 180 190 200
KDFLKNLPKS TVNGVTWTNE TQRQKSHTFN CRMLMKIPHD ILEDMNTSPE
210 220 230 240 250
MRQRYETMQC FALSQPRAMM EEGEDLQSCM ICVARRITTG ERAFPSNPES
260 270 280 290 300
FITRHDLSGK VVSIDTNSLR SSMRPGFEDI IRRCIQRFFS LNDGQSWSQK
310 320 330 340 350
RHYQEAYIHG HAETPVYRFS LADGTIVTAQ TKSKLFRNPV TNDRHSFVST
360 370 380 390 400
HFLQREQNGY RPNPNPVGQG VRPPAAGCNS SVGSMNMSPN QGLQMLSSRT
410 420 430 440 450
YGLADPSTTG QMTGARYGAA GSIASMNPGP GMQSPSSYQN SNYGLNMSSP
460 470 480 490 500
PHGSPGLGSN QQNIMISPRN RGSPKMASHQ FSPVAGVHSP MGSSGSTGNH
510 520 530 540 550
SFSSSSLSAL QAISEGVGTS LLSTLSSPGP KLDNSPNMNI TQPSKVSSQD
560 570 580 590 600
SKSPLGLYCD QNPVESSMCQ SNSRDHLNDK ESKESSVEGS ENQRGPLESK
610 620 630 640 650
GHKKLLQLLT CSSDDRGHSS LTNSPLDSGC KDSAISVTSP SGVSSSTSGG
660 670 680 690 700
VSSTSNMHGS LLQEKHRILH KLLQNGNSPA EVAKITAEAT GKDTSSTASC
710 720 730 740 750
VEGNVKQEQL SPKKKENNAL LRYLLDRDDP SDTLSKELQP KVEGVDGKMS
760 770 780 790 800
QCSSSALPSS SQEKDSKIKT ETNEEGSGDL DNLDAILGDL TSSDFYNNSI
810 820 830 840 850
STNGSNLGTK QQMFQGTNSL GLRSPQSVQS VRPPYNRAVS LDSPVSVGSN
860 870 880 890 900
PSVKNISAFP MLTKQPLMGG NPRMMDGQEN YGSAMGGPNR NVAVNQTPSS
910 920 930 940 950
GDWGLPNSKA SRMEPMNPNS MGRPGTDFNA SLPRPAVGGS MPTMPLRSNS
960 970 980 990 1000
IPGARPVLQQ QQQQQQQMLQ MRPGEIPVGM GVGPYGQGAP SNQPGSWPDG
1010 1020 1030 1040 1050
MLSMEQGPHG TQNRPLLRNS LDDLLGPPSN LEGQSDERAL LDQLHTLLSN
1060 1070 1080 1090 1100
TDATGLEEID RALGIPELVN QGQALEPKQD AFQGQEAAVM MEQKAALYGQ
1110 1120 1130 1140 1150
TYPAQGPPMQ GGFNLQGQSP SFNSMMNQMN QQGNFPLQGM HPRANIMRPR
1160 1170 1180 1190 1200
TNTPKQLRMQ LQQRLQGQQF LNQNRQALEM KMESPSAGGA AVMRPMMQPQ
1210 1220 1230 1240 1250
VSSQGFLITH MVAHRSRKLL INHFRQQRVA MMMQQQQQQQ QQTQAFSPPP
1260 1270 1280 1290 1300
NVTASPSMDG VLAGPSMPQA PPQQFPYPPN YGMGQQPDPA FGRVSSPSNA
1310 1320 1330 1340 1350
MMSSRMGPSQ NPMMQHPQTA PMYQSSDMKG WPSGTLARNS SFPQQQFAPQ
1360 1370 1380 1390
GNPAAYSMVH MNGSSGPMGQ MNMNSVPMTG MPMGPDQKYC
Length:1,390
Mass (Da):151,182
Last modified:February 26, 2008 - v1
Checksum:i31868029DA87F91B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU346674 mRNA Translation: ABY60789.1
RefSeqiNP_001107748.1, NM_001114276.1
UniGeneiSsc.69931

Genome annotation databases

GeneIDi100135659
KEGGissc:100135659

Similar proteinsi

Entry informationi

Entry nameiB0FRD8_PIG
AccessioniPrimary (citable) accession number: B0FRD8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: July 18, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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