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Entry version 62 (08 May 2019)
Sequence version 1 (26 Feb 2008)
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Protein
Submitted name:

TPR domain protein

Gene

AM1_1237

Organism
Acaryochloris marina (strain MBIC 11017)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
AMAR329726:GCZJ-1215-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

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CAZyi
GT41 Glycosyltransferase Family 41

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
TPR domain proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:AM1_1237Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcaryochloris marina (strain MBIC 11017)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri329726 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesAcaryochloridaceaeAcaryochloris
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000268 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
329726.AM1_1237

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1235 – 1404TPR_REGIONInterPro annotationAdd BLAST170
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1235 – 1268TPRPROSITE-ProRule annotationAdd BLAST34
Repeati1269 – 1302TPRPROSITE-ProRule annotationAdd BLAST34
Repeati1303 – 1336TPRPROSITE-ProRule annotationAdd BLAST34
Repeati1337 – 1370TPRPROSITE-ProRule annotationAdd BLAST34
Repeati1371 – 1404TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1235 – 1255Sequence analysisAdd BLAST21
Coiled coili1461 – 1481Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4107EF5 Bacteria
COG3914 LUCA

Database of Orthologous Groups

More...
OrthoDBi
288402at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.25.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017481 CHP03032
IPR037919 OGT
IPR029489 OGT/SEC/SPY_C
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR001440 TPR_1
IPR019734 TPR_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR44366 PTHR44366, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16261 DUF4915, 1 hit
PF13844 Glyco_transf_41, 4 hits
PF00515 TPR_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03032 TIGR03032, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005 TPR, 5 hits
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B0C414-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKRTASSSG HDITADRQFI PWLAQQKISI ACTTYQTSRL MLLGVSPDGR
60 70 80 90 100
TISGFERIFD RAMGLYTTTD RLYLSSKYQI WRFDNVLSGQ QQHNGYDKLY
110 120 130 140 150
IPRIGYTTGD LDIHDIVEVE RGIDGTPWQE TLPVPFVFVS TLLNCIATVS
160 170 180 190 200
DHYSCQPLWK PPFISRIINE DRCHLNGLAA VNGQPRYVTA VSRSDIIDGW
210 220 230 240 250
RDRRQDGGLV MDLSTNEIVA TGFSMPHSPR WYRDRLWLLN SGRGELGYVD
260 270 280 290 300
LRTGTFEPIA FCPGYLRGLA FWGDFAIVGL SQPRNGDKTF SGLPLDDILK
310 320 330 340 350
AKDASPRCGL MVINLNTGAI EHWLRFEGII TELYDVQILP QVQRPMALGF
360 370 380 390 400
QSEEIAQLIT LGPQVPDPPQ PNPTVSPAPP KPPTTLTQPE DQPELADLRQ
410 420 430 440 450
HRQHLVQQWL NLPLEQLEAA YGGELGQAHR TLVNHDLRYE PLTAAEQAFI
460 470 480 490 500
EPLMTALTTH PVQSLLALMP YRAAYQLPER WFEPITIPSW LVNDYLAYMQ
510 520 530 540 550
AVPLFFQAVG ESEQYAQYLN HWFTFIHRKI HQNLNSASWQ SVAAVAAEAV
560 570 580 590 600
FAPIYFNDLN LKDTFIKWAA ITEFSLEHRG MTVHQHGSPR PSHRSKIRLG
610 620 630 640 650
VLNQAYSPHS ETFSTLPFYE HLDRQQFEII LYAESSQDHP LEAYCRSRCD
660 670 680 690 700
QFVLLPQDLP ESVQRIRNDD LDILLFGINI AVGNKSTARL AMYRLARVQV
710 720 730 740 750
SANSSPVTSG INNIDYYLSG ELTTPAETFQ SQYSEKLVTW AGPSCCYRFP
760 770 780 790 800
PSAQQPTAAS YYRRDLNIAD DAVVFVSGAN FFKLIPELRI TWTQILAAVP
810 820 830 840 850
NSVLLLYPFS AWSHHYPVSA FRNHMAALFA GDGIDPSRLI IQDPIPNREQ
860 870 880 890 900
VKQLLQIADV YLDAYPFTGV TSLLDPLEVG LPVVTQAGHS LRSRQGPALL
910 920 930 940 950
ESIDLTDLIA TDEQGYVELA IQLGQDSTRR QQYRTLIQQK MAANPAFMDS
960 970 980 990 1000
PAYGAQVGTL LQQLLPSSFA ELEEEHPPSA SRRRQRVIAF SLWGANPKYT
1010 1020 1030 1040 1050
TGALKNADLA PTLYPGWICR FYVDQTVPSE VVNQLKARSH VEVIQLDGDR
1060 1070 1080 1090 1100
GWKMSFARFL PAADPDVEVL ICRDADSRLN LREKAAVEAW LQSPQKYHIM
1110 1120 1130 1140 1150
RDHPRHNVPM LAGMWGVKGN VLDMELLVEQ HLVDQADLGL RYGIDQHFLA
1160 1170 1180 1190 1200
TQIYPKTQSS CMVHDEIFLQ NPYPAARQGL EYVGQVFLED ESTLKPIDDL
1210 1220 1230 1240 1250
LQQHLLKNDP LALNGFEPSS PSATPATTLA APSTVQALFE RSRQLKKENK
1260 1270 1280 1290 1300
LTEAEACLRE VIHLYPNHWG AYNNLGTLLQ NQGNIQEAEA CYQQALQLNT
1310 1320 1330 1340 1350
NFAEAHSNLA SIWQLNEQPE RAKAGFYRAL QLKPDYVPAH LNLANLYKEQ
1360 1370 1380 1390 1400
RRMAVAIEHY QKVVVAEPQH TEAHFSLGQI FEYQGKSEEA LACYERALQG
1410 1420 1430 1440 1450
NPETHSLWFF ISLVKIKLCN WQDYEAQVQR LQQMIAESFT AKYTPNPFVL
1460 1470 1480 1490 1500
STFNFPLELH QAAARNQAQN AQRAVAQLRS SLTFAHPCKA TPKLRIGYLS
1510 1520 1530 1540 1550
PDLRDHAVGR LVVDLFPHHN RDQYEIVAYT TVDVEDHITQ QIQTGCDAFV
1560 1570 1580 1590 1600
DLSPLSTEQT AQRIYDDGIQ ILVDLAGYTI GNAASVLSLQ PAPIQAQWLG
1610 1620 1630 1640 1650
YPDTMGAEFI QYALADQWLI SPEIAQSYTE KIVYLPHAFV GSPLAISDRP
1660 1670 1680 1690 1700
MTRAEFGVPE SGFVFCCFNS HYKITPDLFD VWMRILQQVP DSVLWLIEGA
1710 1720 1730 1740 1750
ETVMGNLRTE AKQRGVNPDR LVFAPKIAHE DYLARYGLAD LYLDTFVYNA
1760 1770 1780 1790 1800
GSTAVATCWS GLPMLTCPGP TNASRMGASI CAAAGLESLI CKSVADYEQR
1810 1820 1830 1840 1850
AIHLATHPAE LAEIRNGLKR QLQSPETYPA LFQVEQFVAS LESAFQQMWQ
1860
GYLNDAPLQD VVVSR
Length:1,865
Mass (Da):209,905
Last modified:February 26, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89D763FD7A402472
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000828 Genomic DNA Translation: ABW26274.1

NCBI Reference Sequences

More...
RefSeqi
WP_012161820.1, NC_009925.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABW26274; ABW26274; AM1_1237

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
amr:AM1_1237

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000828 Genomic DNA Translation: ABW26274.1
RefSeqiWP_012161820.1, NC_009925.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi329726.AM1_1237

Protein family/group databases

CAZyiGT41 Glycosyltransferase Family 41

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABW26274; ABW26274; AM1_1237
KEGGiamr:AM1_1237

Phylogenomic databases

eggNOGiENOG4107EF5 Bacteria
COG3914 LUCA
OrthoDBi288402at2

Enzyme and pathway databases

BioCyciAMAR329726:GCZJ-1215-MONOMER

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR017481 CHP03032
IPR037919 OGT
IPR029489 OGT/SEC/SPY_C
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR001440 TPR_1
IPR019734 TPR_repeat
PANTHERiPTHR44366 PTHR44366, 2 hits
PfamiView protein in Pfam
PF16261 DUF4915, 1 hit
PF13844 Glyco_transf_41, 4 hits
PF00515 TPR_1, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 1 hit
TIGRFAMsiTIGR03032 TIGR03032, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 5 hits
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB0C414_ACAM1
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B0C414
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: May 8, 2019
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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