UniProtKB - B0BNJ6 (B0BNJ6_RAT)
Protein
Submitted name:
Jmjd2c protein
Gene
Kdm4c
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- androgen receptor binding Source: RGD
- chromatin binding Source: RGD
- enzyme binding Source: RGD
- histone demethylase activity Source: RGD
- histone demethylase activity (H3-K36 specific) Source: RGD
- histone demethylase activity (H3-K9 specific) Source: RGD
- zinc ion binding Source: RGD
GO - Biological processi
- blastocyst formation Source: RGD
- chromatin remodeling Source: GO_Central
- histone H3-K36 demethylation Source: RGD
- histone H3-K9 demethylation Source: RGD
- negative regulation of histone H3-K9 trimethylation Source: RGD
- positive regulation of cell population proliferation Source: RGD
- positive regulation of gene expression Source: RGD
- positive regulation of neuron differentiation Source: RGD
- regulation of gene expression Source: RGD
- regulation of stem cell differentiation Source: RGD
- regulation of transcription by RNA polymerase II Source: RGD
- stem cell population maintenance Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: Jmjd2c proteinImported |
Gene namesi | |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Organism-specific databases
RGDi | 1307528, Kdm4c |
Subcellular locationi
Nucleus
- histone methyltransferase complex Source: GO_Central
Other locations
- chromatin Source: RGD
- pericentric heterochromatin Source: RGD
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 58 | JmjNInterPro annotationAdd BLAST | 43 | |
Domaini | 144 – 261 | JmjCInterPro annotationAdd BLAST | 118 |
Phylogenomic databases
OrthoDBi | 1186832at2759 |
PhylomeDBi | B0BNJ6 |
Family and domain databases
InterProi | View protein in InterPro IPR003347, JmjC_dom IPR003349, JmjN |
Pfami | View protein in Pfam PF02373, JmjC, 1 hit PF02375, JmjN, 1 hit |
SMARTi | View protein in SMART SM00558, JmjC, 1 hit SM00545, JmjN, 1 hit |
PROSITEi | View protein in PROSITE PS51184, JMJC, 1 hit PS51183, JMJN, 1 hit |
i Sequence
Sequence statusi: Complete.
B0BNJ6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEVVEVESPL NPSCKIMTFR PSMEEFREFN KYLAYMESKG AHRAGLAKVI
60 70 80 90 100
PPKEWKPRQC YDDIDNLLIP APIQQMVTGQ SGLFTQYNIQ KKPMTVKEFR
110 120 130 140 150
QLANSSKYCT PRYLDYEDLE RKYWKNLTFV APIYGADING SIYDEGVDEW
160 170 180 190 200
NIARLNTVLD VVEEECGISI EGVNTPYLYF GMWKTTFAWH TEDMDLYSIN
210 220 230 240 250
YLHFGEPKSW YAIPPEHGKR LERLAQGFFP SSSQGCDAFL RHKMTLISPS
260
VLKKYGIPFD K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC158850 mRNA Translation: AAI58851.1 |
RefSeqi | NP_001100133.3, NM_001106663.3 |
Genome annotation databases
GeneIDi | 298144 |
KEGGi | rno:298144 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC158850 mRNA Translation: AAI58851.1 |
RefSeqi | NP_001100133.3, NM_001106663.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 298144 |
KEGGi | rno:298144 |
Organism-specific databases
CTDi | 23081 |
RGDi | 1307528, Kdm4c |
Phylogenomic databases
OrthoDBi | 1186832at2759 |
PhylomeDBi | B0BNJ6 |
Family and domain databases
InterProi | View protein in InterPro IPR003347, JmjC_dom IPR003349, JmjN |
Pfami | View protein in Pfam PF02373, JmjC, 1 hit PF02375, JmjN, 1 hit |
SMARTi | View protein in SMART SM00558, JmjC, 1 hit SM00545, JmjN, 1 hit |
PROSITEi | View protein in PROSITE PS51184, JMJC, 1 hit PS51183, JMJN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B0BNJ6_RAT | |
Accessioni | B0BNJ6Primary (citable) accession number: B0BNJ6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 26, 2008 |
Last sequence update: | February 26, 2008 | |
Last modified: | April 7, 2021 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |