Sin3b

Functionⁱ

GO - Biological processⁱ

histone deacetylation Source: GO_Central
negative regulation of transcription by RNA polymerase II Source: GO_Central

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactomeⁱ	R-RNO-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-RNO-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Reactomeⁱ

R-RNO-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-RNO-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: RCG38713, isoform CRA_bImported Submitted name: SIN3 transcription regulator family member BImported Submitted name: Sin3b proteinImported
Gene namesⁱ	Name:Sin3bImported ORF Names:rCG_38713Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 16

Organism-specific databases

Rat genome database More...RGDⁱ	1587989 Sin3b

RGDⁱ

1587989 Sin3b

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotation

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000048622 Expressed in 10 organ(s), highest expression level in testis

Bgeeⁱ

ENSRNOG00000048622 Expressed in 10 organ(s), highest expression level in testis

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	B0BNJ0, 1 interactor
STRINGⁱ	10116.ENSRNOP00000064384

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG4204 Eukaryota COG5602 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000007239
HOVERGENⁱ	HBG100510
OMAⁱ	CEMNSAQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G03HY

Family and domain databases

InterProⁱ	View protein in InterPro IPR003822 PAH IPR036600 PAH_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02671 PAH, 2 hits
SUPFAMⁱ	SSF47762 SSF47762, 2 hits
PROSITEⁱ	View protein in PROSITE PS51477 PAH, 2 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

B0BNJ0-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MAHAGGGGSA GRGFGGSRWG RSGSGGHEKL PVHVEDALTY LDQVKIRFGS 
        60         70         80         90        100
DPATYNGFLE IMKEFKSQSI DTPGVIRRVS QLFHEHPDLI VGFNAFLPLG 
       110        120        130        140        150
YRIDIPKNGK LNIQSPLSNQ DNSHSHGDCG EDFKQMSYKE DRGQVPLESD 
       160        170        180        190        200
SVEFNNAISY VNKIKTRFLD HPEIYRSFLE ILHTYQKEQL HTKGRPFRGM 
       210        220        230        240        250
SEEEVFTEVA NLFRGQEDLL SEFGQFLPEA KRSLFTGNGS CEMNSAQKNE 
       260        270        280        290 
EKSLEHKKRS RPSLLRPVSA PAKVGLQLKC AVVWFGYCTA EE

Length:292

Mass (Da):32,743

Last modified:February 26, 2008 - v1

Checksum:ⁱ7D5E0C5ED947968B

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07024847 Genomic DNA No translation available. BC158844 mRNA Translation: AAI58845.1 CH474031 Genomic DNA Translation: EDL90860.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001108510.1, NM_001115038.1
UniGeneⁱ	Rn.216472

Genome annotation databases

Ensemblⁱ	ENSRNOT00000074814; ENSRNOP00000064384; ENSRNOG00000048622
GeneIDⁱ	683381
KEGGⁱ	rno:683381

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
B0BNJ0	Isoform 3 of Paired amphipathic helix protein Sin3b		MOUSE		302	UniRef90_Q62141-3
paired amphipathic helix protein Sin3b isoform X2		MESAU		293
UPI00022F3E3F		CRIGR		293
UPI00038C41B9		MICOH		293
UPI000A313437		MUSPA		293
+5

Protein	Similar proteins		Species	Score	Length	Source
B0BNJ0	Isoform 3 of Paired amphipathic helix protein Sin3b		MOUSE		302	UniRef50_Q62141-3
paired amphipathic helix protein Sin3b isoform X2		MESAU		293
Paired amphipathic helix protein Sin3b (Fragment)		HUMAN		309
SIN3B isoform 12 (Fragment)		PONAB		308
SIN3B isoform 12 (Fragment)		PANTR		308
+17

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07024847 Genomic DNA No translation available. BC158844 mRNA Translation: AAI58845.1 CH474031 Genomic DNA Translation: EDL90860.1
RefSeqⁱ	NP_001108510.1, NM_001115038.1
UniGeneⁱ	Rn.216472

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	B0BNJ0, 1 interactor
STRINGⁱ	10116.ENSRNOP00000064384

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000074814; ENSRNOP00000064384; ENSRNOG00000048622
GeneIDⁱ	683381
KEGGⁱ	rno:683381

Organism-specific databases

CTDⁱ	23309
RGDⁱ	1587989 Sin3b

Phylogenomic databases

eggNOGⁱ	KOG4204 Eukaryota COG5602 LUCA
GeneTreeⁱ	ENSGT00390000007239
HOVERGENⁱ	HBG100510
OMAⁱ	CEMNSAQ
OrthoDBⁱ	EOG091G03HY

Enzyme and pathway databases

Reactomeⁱ	R-RNO-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-RNO-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Reactomeⁱ

R-RNO-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-RNO-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Gene expression databases

Bgeeⁱ	ENSRNOG00000048622 Expressed in 10 organ(s), highest expression level in testis

Bgeeⁱ

ENSRNOG00000048622 Expressed in 10 organ(s), highest expression level in testis

Family and domain databases

InterProⁱ	View protein in InterPro IPR003822 PAH IPR036600 PAH_sf
Pfamⁱ	View protein in Pfam PF02671 PAH, 2 hits
SUPFAMⁱ	SSF47762 SSF47762, 2 hits
PROSITEⁱ	View protein in PROSITE PS51477 PAH, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B0BNJ0_RAT
Accessionⁱ	B0BNJ0Primary (citable) accession number: B0BNJ0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 26, 2008
	Last sequence update:	February 26, 2008
	Last modified:	September 12, 2018
	This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - B0BNJ0 (B0BNJ0_RAT)

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RCG38713, isoform CRA_b

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Functionⁱ

GO - Biological processⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Nucleus

Nucleus

Keywords - Cellular componentⁱ

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

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Annotation systems

Supporting data

UniProtKB - B0BNJ0 (B0BNJ0_RAT)

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RCG38713, isoform CRA_b

Sin3b

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ