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UniProtKB - B0BNJ0 (B0BNJ0_RAT)
Protein
Submitted name:
RCG38713, isoform CRA_b
Gene
Sin3b
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: RGD
- transcription corepressor activity Source: RGD
GO - Biological processi
- cardiac muscle tissue development Source: RGD
- histone deacetylation Source: GO_Central
- negative regulation of transcription, DNA-templated Source: RGD
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- skeletal muscle tissue development Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: RCG38713, isoform CRA_bImportedSubmitted name: SIN3 transcription regulator family member BImportedSubmitted name: Sin3b proteinImported |
Gene namesi | Name:Sin3bImported ORF Names:rCG_38713Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1587989, Sin3b |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- histone deacetylase complex Source: GO_Central
- nucleus Source: RGD
- Sin3 complex Source: GO_Central
Other locations
- autosome Source: RGD
- chromatin Source: GO_Central
- cytoplasm Source: RGD
- X chromosome Source: RGD
- XY body Source: RGD
- Y chromosome Source: RGD
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000048622, Expressed in testis and 22 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | B0BNJ0, 1 interactor |
STRINGi | 10116.ENSRNOP00000064384 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 26 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 241 – 262 | DisorderedSequence analysisAdd BLAST | 22 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 248 – 262 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | KOG4204, Eukaryota |
GeneTreei | ENSGT00940000159560 |
HOGENOMi | CLU_953043_0_0_1 |
OMAi | CEMNSAQ |
OrthoDBi | 253485at2759 |
Family and domain databases
Gene3Di | 1.20.1160.11, 2 hits |
InterProi | View protein in InterPro IPR003822, PAH IPR036600, PAH_sf IPR039774, Sin3-like |
PANTHERi | PTHR12346, PTHR12346, 1 hit |
Pfami | View protein in Pfam PF02671, PAH, 2 hits |
SUPFAMi | SSF47762, SSF47762, 2 hits |
PROSITEi | View protein in PROSITE PS51477, PAH, 2 hits |
i Sequence
Sequence statusi: Complete.
B0BNJ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAHAGGGGSA GRGFGGSRWG RSGSGGHEKL PVHVEDALTY LDQVKIRFGS
60 70 80 90 100
DPATYNGFLE IMKEFKSQSI DTPGVIRRVS QLFHEHPDLI VGFNAFLPLG
110 120 130 140 150
YRIDIPKNGK LNIQSPLSNQ DNSHSHGDCG EDFKQMSYKE DRGQVPLESD
160 170 180 190 200
SVEFNNAISY VNKIKTRFLD HPEIYRSFLE ILHTYQKEQL HTKGRPFRGM
210 220 230 240 250
SEEEVFTEVA NLFRGQEDLL SEFGQFLPEA KRSLFTGNGS CEMNSAQKNE
260 270 280 290
EKSLEHKKRS RPSLLRPVSA PAKVGLQLKC AVVWFGYCTA EE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07024847 Genomic DNA No translation available. BC158844 mRNA Translation: AAI58845.1 CH474031 Genomic DNA Translation: EDL90860.1 |
RefSeqi | NP_001108510.1, NM_001115038.1 |
Genome annotation databases
Ensembli | ENSRNOT00000074814; ENSRNOP00000064384; ENSRNOG00000048622 |
GeneIDi | 683381 |
KEGGi | rno:683381 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07024847 Genomic DNA No translation available. BC158844 mRNA Translation: AAI58845.1 CH474031 Genomic DNA Translation: EDL90860.1 |
RefSeqi | NP_001108510.1, NM_001115038.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | B0BNJ0, 1 interactor |
STRINGi | 10116.ENSRNOP00000064384 |
Genome annotation databases
Ensembli | ENSRNOT00000074814; ENSRNOP00000064384; ENSRNOG00000048622 |
GeneIDi | 683381 |
KEGGi | rno:683381 |
Organism-specific databases
CTDi | 23309 |
RGDi | 1587989, Sin3b |
Phylogenomic databases
eggNOGi | KOG4204, Eukaryota |
GeneTreei | ENSGT00940000159560 |
HOGENOMi | CLU_953043_0_0_1 |
OMAi | CEMNSAQ |
OrthoDBi | 253485at2759 |
Gene expression databases
Bgeei | ENSRNOG00000048622, Expressed in testis and 22 other tissues |
Family and domain databases
Gene3Di | 1.20.1160.11, 2 hits |
InterProi | View protein in InterPro IPR003822, PAH IPR036600, PAH_sf IPR039774, Sin3-like |
PANTHERi | PTHR12346, PTHR12346, 1 hit |
Pfami | View protein in Pfam PF02671, PAH, 2 hits |
SUPFAMi | SSF47762, SSF47762, 2 hits |
PROSITEi | View protein in PROSITE PS51477, PAH, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | B0BNJ0_RAT | |
Accessioni | B0BNJ0Primary (citable) accession number: B0BNJ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 26, 2008 |
Last sequence update: | February 26, 2008 | |
Last modified: | January 19, 2022 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |