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Protein
Submitted name:

Dopamine receptor 2 protein transcript variant 1

Gene

DRD2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-GGA-390651 Dopamine receptors
R-GGA-418594 G alpha (i) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine receptor 2 protein transcript variant 1Imported
Submitted name:
Dopamine receptor D2 long isoformImported
Gene namesi
Name:DRD2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGALG00000007794 Expressed in 1 organ(s), highest expression level in brain

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000012625

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 420G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST373

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00890000139331
HOGENOMiHOG000239242
HOVERGENiHBG106962
KOiK04145
OMAiDRNWSKP
OrthoDBiEOG091G06VI
TreeFamiTF334382

Family and domain databases

InterProiView protein in InterPro
IPR001922 Dopamine_D2_rcpt
IPR000929 Dopamine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00567 DOPAMINED2R
PR00242 DOPAMINER
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

A9YZQ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPLNLSWYN SGDRNWSKPL NESSADQKPQ YNYYAVLLTL LIFVIVFGNV
60 70 80 90 100
LVCMAVSREK ALQTTTNYLI VSLAVADLLV ATLVMPWVVY LEVVGEWRFS
110 120 130 140 150
RIHCDIFVTL DVMMCTASIL NLCAISIDRY TAVAMPMLYN TRYSSKRRVT
160 170 180 190 200
VMIAVVWVLS FAISSPILFG LNKADEKECI IANPAFVVYS SVVSFYVPFI
210 220 230 240 250
VTLLVYVQIY IVLRKRRKRV TTKRSSHVLD SDTQAPLKDK CTHPEDVKLC
260 270 280 290 300
TVIVKSNGSF QVNKRKVEAE SHIEMEMEMV SSTSPPERTL AKPAAPSNHQ
310 320 330 340 350
LVVPIASRRC TLDSPGKVEK NGHAKENLHT AKVFEIQSMP NGKTRSTLLK
360 370 380 390 400
AMNRRKLSQQ KEKKATQMLA IVLGVFIICW LPFFITHILN MHCDCNIPPA
410 420 430
MYSAFTWLGY VNSAVNPIIY TTFNIEFRKA FMKILHC
Length:437
Mass (Da):49,543
Last modified:February 5, 2008 - v1
Checksum:i445259E9E2162DB7
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5PDB7A0A1D5PDB7_CHICK
Dopamine receptor D2
DRD2
399Annotation score:
A0A1D5PQP0A0A1D5PQP0_CHICK
Dopamine receptor D2
DRD2
375Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000117 Genomic DNA No translation available.
EU313425 mRNA Translation: ABY28377.1
MF967037 mRNA Translation: AUL82233.1
AB688630 Genomic DNA Translation: BAP27873.1
AB688631 Genomic DNA Translation: BAP27874.1
AB688632 Genomic DNA Translation: BAP27875.1
AB688633 Genomic DNA Translation: BAP27876.1
AB688634 Genomic DNA Translation: BAP27877.1
AB688636 Genomic DNA Translation: BAP27878.1
AB688637 Genomic DNA Translation: BAP27879.1
AB688638 Genomic DNA Translation: BAP27880.1
AB688639 Genomic DNA Translation: BAP27881.1
AB688642 Genomic DNA Translation: BAP27882.1
AB688643 Genomic DNA Translation: BAP27883.1
AB688646 Genomic DNA Translation: BAP27886.1
AB688647 Genomic DNA Translation: BAP27887.1
AB688649 Genomic DNA Translation: BAP27889.1
AB688650 Genomic DNA Translation: BAP27890.1
AB688651 Genomic DNA Translation: BAP27891.1
AB688652 Genomic DNA Translation: BAP27892.1
AB688653 Genomic DNA Translation: BAP27893.1
AB688654 Genomic DNA Translation: BAP27894.1
AB688656 Genomic DNA Translation: BAP27896.1
AB688657 Genomic DNA Translation: BAP27897.1
AB688658 Genomic DNA Translation: BAP27898.1
RefSeqiNP_001106761.1, NM_001113290.1
XP_015153515.1, XM_015298029.1
UniGeneiGga.47299

Genome annotation databases

EnsembliENSGALT00000012639; ENSGALP00000012625; ENSGALG00000007794
GeneIDi428252
KEGGigga:428252

Similar proteinsi

Entry informationi

Entry nameiA9YZQ5_CHICK
AccessioniPrimary (citable) accession number: A9YZQ5
Secondary accession number(s): F1NP41
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 12, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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