Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative hydroxypyruvate isomerase

Gene

hyi

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei147Proton donor/acceptorUniRule annotation1
Active sitei246Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:hyiImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5847279 hyi

Expressioni

Gene expression databases

BgeeiENSXETG00000002253 Expressed in 12 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000004789

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 215AP_endonuc_2InterPro annotationAdd BLAST194

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
HOGENOMiHOG000218197
HOVERGENiHBG056845
KOiK01816
OMAiCEYRPRA
OrthoDBiEOG091G0KZU
TreeFamiTF312858

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

A9ULD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHFSANISWL FQDVPDFPGR IEAASQSGFR AVEVAWPYAS DRTLFKAALN
60 70 80 90 100
NHNTSLVLLN TPPGNIEAGE LGLAAVPGRQ DEFRTGLNEA VRWASDLGCD
110 120 130 140 150
RIHIMAGRVP LGLERQNIEE EMEETFIENL QYAADILAQA GMVGLLEPIN
160 170 180 190 200
SLISEPRYFL NTPQHAASIL QKVKRPNLKL QMDLYHWQIM GGNLTQNIKT
210 220 230 240 250
YFPLIGHVQI AQVPHRNEPD SPGELNFMYL FDLLQELGYQ GYVGCEYKPQ
260 270
GDTAKGLGWM KKYLKYCHVD NKTN
Length:274
Mass (Da):30,877
Last modified:February 5, 2008 - v1
Checksum:i567DFC32CAC2E94F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01002112 Genomic DNA No translation available.
AAMC01002113 Genomic DNA No translation available.
AAMC01002114 Genomic DNA No translation available.
BC157213 mRNA Translation: AAI57214.1
BC171074 mRNA Translation: AAI71074.1
BC171076 mRNA Translation: AAI71076.1
RefSeqiNP_001107362.1, NM_001113890.1
XP_012816018.1, XM_012960564.2
XP_012816019.1, XM_012960565.1
UniGeneiStr.27602

Genome annotation databases

EnsembliENSXETT00000004789; ENSXETP00000004789; ENSXETG00000002253
GeneIDi100135187
KEGGixtr:100135187

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01002112 Genomic DNA No translation available.
AAMC01002113 Genomic DNA No translation available.
AAMC01002114 Genomic DNA No translation available.
BC157213 mRNA Translation: AAI57214.1
BC171074 mRNA Translation: AAI71074.1
BC171076 mRNA Translation: AAI71076.1
RefSeqiNP_001107362.1, NM_001113890.1
XP_012816018.1, XM_012960564.2
XP_012816019.1, XM_012960565.1
UniGeneiStr.27602

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000004789

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000004789; ENSXETP00000004789; ENSXETG00000002253
GeneIDi100135187
KEGGixtr:100135187

Organism-specific databases

CTDi81888
XenbaseiXB-GENE-5847279 hyi

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
HOGENOMiHOG000218197
HOVERGENiHBG056845
KOiK01816
OMAiCEYRPRA
OrthoDBiEOG091G0KZU
TreeFamiTF312858

Gene expression databases

BgeeiENSXETG00000002253 Expressed in 12 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA9ULD4_XENTR
AccessioniPrimary (citable) accession number: A9ULD4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 7, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again