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Protein

Eukaryotic translation initiation factor 3 subunit C

Gene

PHYPA_004145

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorUniRule annotationSAAS annotation
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit CUniRule annotation
Short name:
eIF3cUniRule annotation
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 8UniRule annotation
eIF3 p110UniRule annotation
Gene namesi
ORF Names:PHYPA_004145Imported, PHYPADRAFT_190037Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
Proteomesi
  • UP000006727 Componenti: Chromosome 3

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.UniRule annotationSAAS annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3218.PP1S140_60V6.1

Structurei

3D structure databases

ProteinModelPortaliA9SZ44
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini622 – 794PCIInterPro annotationAdd BLAST173

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili152 – 172Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the eIF-3 subunit C family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1076 Eukaryota
ENOG410XRU3 LUCA
InParanoidiA9SZ44
OMAiAMKINDC

Family and domain databases

HAMAPiMF_03002 eIF3c, 1 hit
InterProiView protein in InterPro
IPR027516 EIF3C
IPR008905 EIF3C_N_dom
IPR000717 PCI_dom
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR13937 PTHR13937, 1 hit
PfamiView protein in Pfam
PF05470 eIF-3c_N, 1 hit
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequencei

Sequence statusi: Complete.

A9SZ44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASKFWGNSD SESDEDSQLS DHDEDEVIIG GEEAEKIADK YRIGGDSDSD
60 70 80 90 100
ESDDQRRVVR SAKDKRFDEL AQTTVQIQNQ ININDWVQLQ ESFERLNKQL
110 120 130 140 150
EKVNRLTESQ VAPRVYIKGL VLLEDYLNQT LLNKEAKKKM SPSNAKALNF
160 170 180 190 200
MKQKLKKNNQ LYQADIEKFR ANPVSDVESD SDDGENADDV FSDDDDDDLP
210 220 230 240 250
EDRPEDLSDD ADNPDDGGDW TSAQKKPKEM FPKLDPGQIS WEMVDKKLKE
260 270 280 290 300
IIVARGRKGT DRAEQVEQLS YLARCAKTPA QKLEVMVHVV SAQFDVNPSL
310 320 330 340 350
STHMPIAVWK KCVQNILVIL DILAQYPNIV MDETSEPEVE NETEKGADHE
360 370 380 390 400
GPIHVWGNVV AFLERCDDEL FKSLQCIDPH TKDYVERLRD EPLFMTLAQN
410 420 430 440 450
VQQYVERLGD MRAAARVALR RVEHVYYKPQ EVYEAMRKLS ELQSRSGAAA
460 470 480 490 500
EAGVEGEEED GDVAMKGVTE TKGPASFVVT PEIVPRRASF PSVNRKLMDQ
510 520 530 540 550
LVTLIYKYGD ERTKARAMLC DIYQHAISDE YYTARDLLLM SHLQDSVMNM
560 570 580 590 600
DISTQLLFNR AMAQLGLCAF RESLVMEAHN CLSELYAGGR VKELLAQGVQ
610 620 630 640 650
QSRWHEKNPE QEKLERRRQM PFHMHINLEL LEAVHLVTAM LLEVPNMASS
660 670 680 690 700
MHDMKRKVIS KPFRRLLDIN EKQTFTGPPE NVRDHVMAAT QALSKGDWEK
710 720 730 740 750
AVEVIQSMDV WKLLGKREAI LQMLRGKMQE EALRTYIFTY SPYFDSLSLD
760 770 780 790 800
QLMTMFGLPE AQVHSIVSKM MIAEELHASW DQPTRCIVTH NVEPTRLQAL
810 820 830 840 850
ASQFAEKLNV LVESNEKAFD ARTGGGGLEG MGRRNRDTQD YADAAGGRRG
860 870 880 890 900
GDFGGGRGGN KGGRGGRGGR DNFGGGRGGR DNNQGGYNNY NRGGQGGGGR
910 920 930 940 950
GYSSGYQSTR YQDAYSSVGR TPYQTGPTAA GINRGQQAAD AGGRMVSLSR

MGSRF
Length:955
Mass (Da):107,323
Last modified:February 5, 2008 - v1
Checksum:i5E05944B64B616DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545029 Genomic DNA Translation: EDQ63561.1
ABEU02000003 Genomic DNA Translation: PNR57152.1
RefSeqiXP_001771647.1, XM_001771595.1

Genome annotation databases

EnsemblPlantsiPNR57152; PNR57152; PHYPA_004145
GrameneiPNR57152; PNR57152; PHYPA_004145

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545029 Genomic DNA Translation: EDQ63561.1
ABEU02000003 Genomic DNA Translation: PNR57152.1
RefSeqiXP_001771647.1, XM_001771595.1

3D structure databases

ProteinModelPortaliA9SZ44
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3218.PP1S140_60V6.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiPNR57152; PNR57152; PHYPA_004145
GrameneiPNR57152; PNR57152; PHYPA_004145

Phylogenomic databases

eggNOGiKOG1076 Eukaryota
ENOG410XRU3 LUCA
InParanoidiA9SZ44
OMAiAMKINDC

Family and domain databases

HAMAPiMF_03002 eIF3c, 1 hit
InterProiView protein in InterPro
IPR027516 EIF3C
IPR008905 EIF3C_N_dom
IPR000717 PCI_dom
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR13937 PTHR13937, 1 hit
PfamiView protein in Pfam
PF05470 eIF-3c_N, 1 hit
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA9SZ44_PHYPA
AccessioniPrimary (citable) accession number: A9SZ44
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: October 10, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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