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Protein

V-type proton ATPase subunit a

Gene

PHYPADRAFT_214893

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
ORF Names:PHYPADRAFT_214893Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei417 – 441HelicalUniRule annotationAdd BLAST25
Transmembranei462 – 479HelicalUniRule annotationAdd BLAST18
Transmembranei548 – 566HelicalUniRule annotationAdd BLAST19
Transmembranei578 – 601HelicalUniRule annotationAdd BLAST24
Transmembranei636 – 655HelicalUniRule annotationAdd BLAST20
Transmembranei757 – 777HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3218.PP1S107_75V6.1

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili86 – 120Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

InParanoidiA9SRI3

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit

Sequencei

Sequence statusi: Complete.

A9SRI3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVAMDLFRSE EMTLVQLIIP AESAHDTVTY LAELGLLQFK DLNPERSPFQ
60 70 80 90 100
RTYANQVKRC GEMSRKIRYF QDQITKSGRT AAYRPLRDKD IGVDELEAKL
110 120 130 140 150
TDLEAELLEI NANTDKLQRT HSELTEFQLV LHKAGAFFSS VRNAANTVQQ
160 170 180 190 200
RADIENGSSI GEAIDRPLLQ EQEMQTEPSK QARLGFITGV IPKIKAASFE
210 220 230 240 250
RILFRATRGN MFLKQASIED AVVDPATGEK IEKTVFVIFF SGERAKTKIS
260 270 280 290 300
KICDAFGANC YPFPEESSRQ GHMKTEVDNR LLDLQHTLDA GINHRDNVLN
310 320 330 340 350
SIGNNLDQWT VMVRREKAVY HTLNMLSIDV TRKCLVAEGW CPVSAKPKIQ
360 370 380 390 400
DALQRAAFVS NSQVNTIFQV LHTKESPPSY FETNKFTNAF QEIVEAYGVG
410 420 430 440 450
RYQEANPGCF TIITFPFLFA VMFGDWGHGI CLLLGALYLV LNEKKLGSKK
460 470 480 490 500
LGDIMEMAYG GRYVILLMAI FSIYTGFIYN EFFSVPFGFF GGSAYRCPDS
510 520 530 540 550
QYSIESCPMA TTSGMEKWSY EPYAFGVDPI WHGSRSELPF TNSLKMKMSI
560 570 580 590 600
LLGIAQMNLG ILLSYFNARY FRSALDVWYQ FIPQLLFLNA LFGYLSFLIV
610 620 630 640 650
LKWCQGSKPD LYHVMIYMFL SPTEDLGENQ LFMGQTFVQI VLLLVALVAV
660 670 680 690 700
PWMLFPKPLI LRKRHVQKMQ GRAYGMLRES DTESTDLEID GEHDEEEFEF
710 720 730 740 750
GEVLVHQMIH TIEFVLGAVS NTASYLRLWA LSLAHAQLSA VFYDRVLMFA
760 770 780 790 800
WGYTNPIIRL IGLIVFASVT FGVLLLMETL SAFLHALRLH WVEFQNKFYL
810 820
GDGYKFQPFS FRTLSEEDDL
Length:820
Mass (Da):93,326
Last modified:February 5, 2008 - v1
Checksum:i331AF7FA88B299CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544996 Genomic DNA Translation: EDQ66245.1
RefSeqiXP_001768891.1, XM_001768839.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544996 Genomic DNA Translation: EDQ66245.1
RefSeqiXP_001768891.1, XM_001768839.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3218.PP1S107_75V6.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiA9SRI3

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA9SRI3_PHYPA
AccessioniPrimary (citable) accession number: A9SRI3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 18, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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