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Protein

Phosphoinositide phospholipase C

Gene

PLC4

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation, TransducerSAAS annotation
Biological processLipid degradationUniRule annotationSAAS annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoinositide phospholipase CUniRule annotation (EC:3.1.4.11UniRule annotation)
Gene namesi
Name:PLC4Imported
ORF Names:PHYPA_006452Imported, PHYPADRAFT_202996Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)Imported
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
Proteomesi
  • UP000006727 Componenti: Chromosome 4

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi3218.PP1S13_9V6.2

Structurei

3D structure databases

ProteinModelPortaliA9RJG9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini148 – 293PI-PLC X-boxInterPro annotationAdd BLAST146
Domaini407 – 495PI-PLC Y-boxInterPro annotationAdd BLAST89
Domaini514 – 603C2InterPro annotationAdd BLAST90

Phylogenomic databases

eggNOGiKOG0169 Eukaryota
ENOG410XPSW LUCA
InParanoidiA9RJG9
OMAiFRCTDEY

Family and domain databases

Gene3Di2.60.40.150, 1 hit
3.20.20.190, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001192 PI-PLC_fam
IPR017946 PLC-like_Pdiesterase_TIM-brl
IPR000909 PLipase_C_PInositol-sp_X_dom
IPR001711 PLipase_C_Pinositol-sp_Y
PANTHERiPTHR10336 PTHR10336, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF00388 PI-PLC-X, 1 hit
PF00387 PI-PLC-Y, 1 hit
PRINTSiPR00390 PHPHLIPASEC
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00148 PLCXc, 1 hit
SM00149 PLCYc, 1 hit
SUPFAMiSSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50007 PIPLC_X_DOMAIN, 1 hit
PS50008 PIPLC_Y_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

A9RJG9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSIARLKEA CSHCLPPTVA PYHAVCTPPA LVTRVFEQAT IGRDVRVIGP
60 70 80 90 100
ADLAKFMTDW QGDRNATEER ATSLMADFNF LKSTASRALR IPGLSHSSKY
110 120 130 140 150
SLSSRHSGSK HGQSAPETPT FDIATFLKFL LHPEFNGHRV PVSKTPTDDM
160 170 180 190 200
NAPLSDYYIF SSHNTYLMGN QLCSPSSTAP IVKALLDGCR VIELDCWNGS
210 220 230 240 250
NKRIDVLHGG TLTKAVPFED CVKAIKDNAF TTSAYPVVVT IESHLDLEHQ
260 270 280 290 300
KEAARVLNKI LGNIMFVPPP NELPPQSFRS PEQLKHRIII SDKPPGDALL
310 320 330 340 350
SQAANEPEFA QQTLLHEVVR DPSPDNRHEH RHGRRGKKKK LRRRQSQIAE
360 370 380 390 400
SRIQKLPSGK LGDSGRPAIA NDPAFDELLY IHCQKPTEMA TEQKKGGPLI
410 420 430 440 450
KGQHAIMANL SESQLDDLIE DHTDSLIEFS KTNLTRVYPF GLRVTSSNAD
460 470 480 490 500
PMDAWEHGVQ VAAINMQGRD RPVWISKAIF SRNGGCGYVK KPDILLPESN
510 520 530 540 550
MDHKSLMNLQ PKLELKVTVL LGTDWHKNYD VFKKPDYFVK VAIHGMHDDE
560 570 580 590 600
QKFKTHVCKR SREPHWEDEE FVFQIRVPEL AILRLEVREY DRIVRDDMVG
610 620 630
QSCVPVTELR QGIRAVQLAS KKGEPRSSKL LCHFITRTL
Length:639
Mass (Da):71,801
Last modified:February 5, 2008 - v1
Checksum:i8D950EA54E741A45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544902 Genomic DNA Translation: EDQ80831.1
ABEU02000004 Genomic DNA Translation: PNR55555.1
RefSeqiXP_001754381.1, XM_001754329.1

Genome annotation databases

EnsemblPlantsiPNR55555; PNR55555; PHYPA_006452
GrameneiPNR55555; PNR55555; PHYPA_006452

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544902 Genomic DNA Translation: EDQ80831.1
ABEU02000004 Genomic DNA Translation: PNR55555.1
RefSeqiXP_001754381.1, XM_001754329.1

3D structure databases

ProteinModelPortaliA9RJG9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3218.PP1S13_9V6.2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiPNR55555; PNR55555; PHYPA_006452
GrameneiPNR55555; PNR55555; PHYPA_006452

Phylogenomic databases

eggNOGiKOG0169 Eukaryota
ENOG410XPSW LUCA
InParanoidiA9RJG9
OMAiFRCTDEY

Family and domain databases

Gene3Di2.60.40.150, 1 hit
3.20.20.190, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001192 PI-PLC_fam
IPR017946 PLC-like_Pdiesterase_TIM-brl
IPR000909 PLipase_C_PInositol-sp_X_dom
IPR001711 PLipase_C_Pinositol-sp_Y
PANTHERiPTHR10336 PTHR10336, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF00388 PI-PLC-X, 1 hit
PF00387 PI-PLC-Y, 1 hit
PRINTSiPR00390 PHPHLIPASEC
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00148 PLCXc, 1 hit
SM00149 PLCYc, 1 hit
SUPFAMiSSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50007 PIPLC_X_DOMAIN, 1 hit
PS50008 PIPLC_Y_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA9RJG9_PHYPA
AccessioniPrimary (citable) accession number: A9RJG9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: October 10, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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