Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 21 (23 Feb 2022)
Sequence version 2 (31 May 2011)
Previous versions | rss
Add a publicationFeedback
Protein

CSC1-like protein ERD4

Gene

ERD4

Organism
Brassica juncea (Indian mustard) (Sinapis juncea)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as an osmosensitive calcium-permeable cation channel.

By similarity1 Publication

Caution

Was originally thought to possess 2 RRM (RNA recognition motif) domains and to bind RNA (PubMed:22431979). It seems to be in disagreement with the supposed ion transporter function.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CSC1-like protein ERD4
Alternative name(s):
Protein EARLY-RESPONSIVE TO DEHYDRATION STRESS 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERD4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBrassica juncea (Indian mustard) (Sinapis juncea)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3707 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 5CytoplasmicSequence analysis5
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Topological domaini27 – 90ExtracellularSequence analysisAdd BLAST64
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Topological domaini112 – 148CytoplasmicSequence analysisAdd BLAST37
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Topological domaini170 – 364ExtracellularSequence analysisAdd BLAST195
Transmembranei365 – 385HelicalSequence analysisAdd BLAST21
Topological domaini386 – 416CytoplasmicSequence analysisAdd BLAST31
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Topological domaini438 – 456ExtracellularSequence analysisAdd BLAST19
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Topological domaini478 – 508CytoplasmicSequence analysisAdd BLAST31
Transmembranei509 – 529HelicalSequence analysisAdd BLAST21
Topological domaini530 – 572ExtracellularSequence analysisAdd BLAST43
Transmembranei573 – 593HelicalSequence analysisAdd BLAST21
Topological domaini594 – 614CytoplasmicSequence analysisAdd BLAST21
Transmembranei615 – 635HelicalSequence analysisAdd BLAST21
Topological domaini636 – 637ExtracellularSequence analysis2
Transmembranei638 – 658HelicalSequence analysisAdd BLAST21
Topological domaini659 – 723CytoplasmicSequence analysisAdd BLAST65

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004298131 – 723CSC1-like protein ERD4Add BLAST723

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A9LIW2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR045122, Csc1-like
IPR032880, Csc1_N
IPR027815, PHM7_cyt
IPR003864, RSN1_7TM

The PANTHER Classification System

More...
PANTHERi
PTHR13018, PTHR13018, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14703, PHM7_cyt, 1 hit
PF02714, RSN1_7TM, 1 hit
PF13967, RSN1_TM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A9LIW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFASFLVSL GTSAIIFVVL MFLFTWLSRR PGNVPVYYPN RILKGMDPWE
60 70 80 90 100
GSSLTRNPFA WIREAFTSTE QDVVKLSGVD TAVYFVFQST VLGIFALSAL
110 120 130 140 150
LLLPTLLPIA ATDNNLETSR SATDTTSNGT FSQLDNLSMA NITKSSSRLW
160 170 180 190 200
AFLGAVYWVS VVTYFMLWKA YKHVAALRAQ ALMTSEEVLP EQFAILVRDI
210 220 230 240 250
PSPPNGETQK EFVDSYFRDI YPETFYRSLV VTENSKINKI WEDLEGYKKK
260 270 280 290 300
LARAEAAFAA TSNRPTNKTG LLGLVGERVD SIDYYTKLIN ESVAKLEAEQ
310 320 330 340 350
RTVLAERQQT AAVVFFTDRV TAALAAQSLH CQMVDKWTVT EAPEPRQLIW
360 370 380 390 400
ENLKIKFFSR IVRQYVIYFL VAITILFYMI PIAFVSAITT LANLQKALPF
410 420 430 440 450
LKPIVDIAFI RTILESYLPQ IALIVFLAML PKFLMFLSKS EGIPSQSHAI
460 470 480 490 500
RATSGKYFYF SVLNVFIGVT LAGSLFENLK ALEEKPNSFI TLLATSLPKS
510 520 530 540 550
ATFFLTYVAL KFFVGYGLEL SRIIPLIIFH LKKKYLCKTE AEVKEAWYPG
560 570 580 590 600
DLSYATRVPS DMLILTITFC YSVIAPLILV FGVIYFGLGW LILRNQALKV
610 620 630 640 650
YVPSYESYGR MWPHIHTRIL AALFLFQLVM FGYLGVKIFV WAILLVPLIF
660 670 680 690 700
ISLIFGYVCR QKFYGGFEHT ALEVACRELK QRPDLEEVFR AYIPHSLSTH
710 720
KGDDHQFKGA MSRYQDYAAI SAA
Length:723
Mass (Da):81,931
Last modified:May 31, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1411FD7763C08C42
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU126607 Genomic DNA Translation: ABX56139.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU126607 Genomic DNA Translation: ABX56139.2

3D structure databases

SMRiA9LIW2
ModBaseiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR045122, Csc1-like
IPR032880, Csc1_N
IPR027815, PHM7_cyt
IPR003864, RSN1_7TM
PANTHERiPTHR13018, PTHR13018, 1 hit
PfamiView protein in Pfam
PF14703, PHM7_cyt, 1 hit
PF02714, RSN1_7TM, 1 hit
PF13967, RSN1_TM, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCSC1L_BRAJU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A9LIW2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: May 31, 2011
Last modified: February 23, 2022
This is version 21 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again