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Protein
Submitted name:

Suppressor of cytokine signaling 4

Gene

socs4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine signaling 4Imported
Gene namesi
Name:socs4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 17

Organism-specific databases

ZFINiZDB-GENE-070720-4 socs4

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000078509

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105871

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini234 – 329SH2InterPro annotationAdd BLAST96
Domaini324 – 373SOCS boxInterPro annotationAdd BLAST50

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
GeneTreeiENSGT00760000119136
HOGENOMiHOG000027791
HOVERGENiHBG054138
OMAiSWSADSY
OrthoDBiEOG091G0ABN
TreeFamiTF321368

Family and domain databases

Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR022252 SOCS4/SOCS5_dom
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF12610 SOCS, 1 hit
PF07525 SOCS_box, 1 hit
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

A9LDR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSERKTKNSD TRPKNLRSWS ADSYIRSIKK RSRGSRHETA PRGEEGDGAD
60 70 80 90 100
EQTARSASCP RRRRERMCSC TIPGETDSDS PCRKALSRRS LRQKFQDAVG
110 120 130 140 150
QCLPLRNHHH HHHHPSGSSR PFSVLLWSKR KIHVSELMED KCPFSPKSEL
160 170 180 190 200
AQCWHLIKKH GTNTKPSLSI ETEPKGPLLS STPPTLLSWE QIGSTGASSL
210 220 230 240 250
DDWDPSFALG DSQCCAHTDY ILVPDLLQIN NSPCYWGVLD RFEAEQLLEG
260 270 280 290 300
QPEGTFLLRD SAQDEYLFSV SFRRYSRSLH ARIEQNGKRF SFDGRDPCMY
310 320 330 340 350
RDSSVTGLLK HYSDPSTCLF FEPLLSRPLP RNFPFSLQHL CRAVICSCTT
360 370 380
YQGIEALPLP YTLRHFLRQY HYRCNGACAV
Length:380
Mass (Da):43,346
Last modified:February 5, 2008 - v1
Checksum:i681787AB8F7A9BCB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU464134 Genomic DNA No translation available.
EF371367 mRNA Translation: ABQ28698.1
RefSeqiNP_001104695.1, NM_001111225.1
UniGeneiDr.143194

Genome annotation databases

EnsembliENSDART00000124426; ENSDARP00000105871; ENSDARG00000078509
GeneIDi797891
KEGGidre:797891

Similar proteinsi

Entry informationi

Entry nameiA9LDR6_DANRE
AccessioniPrimary (citable) accession number: A9LDR6
Secondary accession number(s): F1QN73
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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