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Protein

Molybdenum cofactor guanylyltransferase

Gene

mobA

Organism
Shewanella baltica (strain OS195)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.UniRule annotation

Catalytic activityi

GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei23GTPUniRule annotation1
Binding sitei51GTPUniRule annotation1
Binding sitei69GTPUniRule annotation1
Metal bindingi99MagnesiumUniRule annotation1
Binding sitei99GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 12GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processMolybdenum cofactor biosynthesis
LigandGTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdenum cofactor guanylyltransferaseUniRule annotation (EC:2.7.7.77UniRule annotation)
Short name:
MoCo guanylyltransferaseUniRule annotation
Alternative name(s):
GTP:molybdopterin guanylyltransferaseUniRule annotation
Mo-MPT guanylyltransferaseUniRule annotation
Molybdopterin guanylyltransferaseUniRule annotation
Molybdopterin-guanine dinucleotide synthaseUniRule annotation
Short name:
MGD synthaseUniRule annotation
Gene namesi
Name:mobAUniRule annotation
Ordered Locus Names:Sbal195_4460
OrganismiShewanella baltica (strain OS195)
Taxonomic identifieri399599 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000000770 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000791121 – 196Molybdenum cofactor guanylyltransferaseAdd BLAST196

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA9KW43.
SMRiA9KW43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.UniRule annotation

Sequence similaritiesi

Belongs to the MobA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000280423.
KOiK03752.
OMAiFVPCDVP.
OrthoDBiPOG091H05CW.

Family and domain databases

CDDicd02503. MobA. 1 hit.
Gene3Di3.90.550.10. 1 hit.
HAMAPiMF_00316. MobA. 1 hit.
InterProiView protein in InterPro
IPR025877. MobA-like_NTP_Trfase.
IPR013482. Molybde_CF_guanTrfase.
IPR029044. Nucleotide-diphossugar_trans.
PfamiView protein in Pfam
PF12804. NTP_transf_3. 1 hit.
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR02665. molyb_mobA. 1 hit.

Sequencei

Sequence statusi: Complete.

A9KW43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSQIDAVIL AGGMARRMGG DDKGLVELNG EAMIKHTIDR IKPQVKEILI
60 70 80 90 100
NANRNQTRYA EFGFKVISDE HTGFLGPLAG MITAMGQTDA DYLLVVPCDC
110 120 130 140 150
PLLPTDLVPR MLAAIKAEDA EIAVASDGEY EQPVVLLLKP SLRDSMKAFL
160 170 180 190
EAGERKVDFW YAKHHFVVES FSDQPNAFVN VNTPEQKQRL AMEITK
Length:196
Mass (Da):21,678
Last modified:February 5, 2008 - v1
Checksum:i9D2190C95BA6B7F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000891 Genomic DNA. Translation: ABX51617.1.
RefSeqiWP_006084724.1. NC_009997.1.

Genome annotation databases

EnsemblBacteriaiABX51617; ABX51617; Sbal195_4460.
GeneIDi11774415.
KEGGisbn:Sbal195_4460.

Similar proteinsi

Entry informationi

Entry nameiMOBA_SHEB9
AccessioniPrimary (citable) accession number: A9KW43
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome