UniProtKB - A9JTH4 (A9JTH4_DANRE)
Protein
Submitted name:
Zgc:175226 protein
Gene
slc26a6l
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- anion:anion antiporter activity Source: GO_Central
- bicarbonate transmembrane transporter activity Source: GO_Central
- chloride transmembrane transporter activity Source: GO_Central
- oxalate transmembrane transporter activity Source: GO_Central
- secondary active sulfate transmembrane transporter activity Source: UniProtKB-UniRule
- sodium:bicarbonate symporter activity Source: ZFIN
- sulfate transmembrane transporter activity Source: GO_Central
GO - Biological processi
- chloride transport Source: ZFIN
- intracellular pH elevation Source: InterPro
Keywordsi
Biological process | TransportUniRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Zgc:175226 proteinImported |
Gene namesi | Name:slc26a6lImported ORF Names:zgc:175226Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-080220-10, slc26a6l |
Subcellular locationi
Other locations
- Membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 95 – 120 | HelicalUniRule annotationAdd BLAST | 26 | |
Transmembranei | 175 – 197 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 254 – 272 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 284 – 303 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 330 – 351 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 372 – 395 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 407 – 425 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 469 – 498 | HelicalUniRule annotationAdd BLAST | 30 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 522 – 785 | STASInterPro annotationAdd BLAST | 264 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 570 – 603 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 570 – 592 | BasicSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
OrthoDBi | 690428at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR018045, S04_transporter_CS IPR011547, SLC26A/SulP_dom IPR001902, SLC26A/SulP_fam IPR030323, SLC26A6 IPR002645, STAS_dom IPR036513, STAS_dom_sf |
PANTHERi | PTHR11814, PTHR11814, 1 hit PTHR11814:SF113, PTHR11814:SF113, 1 hit |
Pfami | View protein in Pfam PF01740, STAS, 1 hit PF00916, Sulfate_transp, 1 hit |
SUPFAMi | SSF52091, SSF52091, 1 hit |
TIGRFAMsi | TIGR00815, sulP, 1 hit |
PROSITEi | View protein in PROSITE PS01130, SLC26A, 1 hit PS50801, STAS, 1 hit |
i Sequence
Sequence statusi: Complete.
A9JTH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDSRHEEYHV KREVINEQRL KERSQRMNPS QINLPISHRL KTSLSCSVPR
60 70 80 90 100
IKRSIVGFLP VLSWLPRYSI WDYGMPDLIS GISVGIMHLP QGMAYALLAS
110 120 130 140 150
LPPVFGLYTS LYPSLIYFIF GTSRHISVGT FTILSIMIGS VTERLAPDTD
160 170 180 190 200
FLIYNGTNVT GEVDIASRDL YRVQVAAAAT VLGGLIQVVL GLVQFGFVGT
210 220 230 240 250
YLSEPLVRGY TTAASAHAVV AQLKYILGVS PKRFNGPLSI VYTLVDLFTL
260 270 280 290 300
LPETHLPTLV ASVVSIVVLI TAKELNNALK KKMIIPIPVE LCTIVVATVI
310 320 330 340 350
SFYTRLNESY KISVVGDIPS GLQPPSVPNV YIFSEVVLDA FAMAIVGYAI
360 370 380 390 400
SISLGKTFAL KHGYKVESNQ ELVALGLSNT VGGFFQCFSV CSSMSRSLIQ
410 420 430 440 450
ESTGGKTQIA GVVSGVIVLV TVLKLGSLFQ ELPKAVLSAI VFVNLKGMFK
460 470 480 490 500
QYYDIVTLWR SNKIDLLIWL VTFVSTVLFN LDMGLGASMG FALLTVIFRT
510 520 530 540 550
QRPSYALLGH LPGTELYLDM ETHKEVREVP GITIFRSSAT MYFANAELYL
560 570 580 590 600
EALKKKSGLD IGKMLTYKRR QEAKQKRRER RAERRARREA KRQKKAFREA
610 620 630 640 650
SQRSKHAVFS VEEEAGQLSD MNGDLHREAE IGWKERENNT VFVIPETART
660 670 680 690 700
SDGQHTWMYL KGTDPDTATL GSVSDLHDAD VTTIDSSSED TLSRDLERVS
710 720 730 740 750
LGSLGKWTWD IHSIILDLST ANFIDTVAIK TLRNIFHDFG EIDVHIYMAG
760 770 780 790 800
CQELVMKQLE RGGFFSDVIT EACVFATVHD AVLYCVKHHG AATINGHENA
LDMSGTRL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC155340 mRNA Translation: AAI55341.1 |
RefSeqi | NP_001107889.1, NM_001114417.1 |
Genome annotation databases
GeneIDi | 559448 |
KEGGi | dre:559448 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC155340 mRNA Translation: AAI55341.1 |
RefSeqi | NP_001107889.1, NM_001114417.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 559448 |
KEGGi | dre:559448 |
Organism-specific databases
CTDi | 559448 |
ZFINi | ZDB-GENE-080220-10, slc26a6l |
Phylogenomic databases
OrthoDBi | 690428at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR018045, S04_transporter_CS IPR011547, SLC26A/SulP_dom IPR001902, SLC26A/SulP_fam IPR030323, SLC26A6 IPR002645, STAS_dom IPR036513, STAS_dom_sf |
PANTHERi | PTHR11814, PTHR11814, 1 hit PTHR11814:SF113, PTHR11814:SF113, 1 hit |
Pfami | View protein in Pfam PF01740, STAS, 1 hit PF00916, Sulfate_transp, 1 hit |
SUPFAMi | SSF52091, SSF52091, 1 hit |
TIGRFAMsi | TIGR00815, sulP, 1 hit |
PROSITEi | View protein in PROSITE PS01130, SLC26A, 1 hit PS50801, STAS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A9JTH4_DANRE | |
Accessioni | A9JTH4Primary (citable) accession number: A9JTH4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 5, 2008 |
Last sequence update: | February 5, 2008 | |
Last modified: | December 2, 2020 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |