UniProtKB - A9JTH0 (A9JTH0_DANRE)
Protein
Submitted name:
Organic cation transporter 2
Gene
oct2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Enzyme and pathway databases
Reactomei | R-DRE-2161517, Abacavir transmembrane transport R-DRE-549127, Organic cation transport |
Names & Taxonomyi
Protein namesi | Submitted name: Organic cation transporter 2ImportedSubmitted name: Zgc:175176 proteinImported |
Gene namesi | Name:oct2Imported ORF Names:zgc:175176Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-080204-92, oct2 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 44 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 144 – 161 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 168 – 190 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 202 – 220 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 232 – 249 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 255 – 273 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 341 – 362 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 368 – 389 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 396 – 415 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSDARG00000058775, Expressed in muscle organ and 20 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 94 – 510 | MFSInterPro annotationAdd BLAST | 417 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00940000155089 |
HOGENOMi | CLU_001265_33_5_1 |
OMAi | FAKGAWT |
OrthoDBi | 762280at2759 |
TreeFami | TF315847 |
Family and domain databases
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
A9JTH0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNFDELLQH AGDFGFYQKR ISVLGSLPIL LLAFVLIGVV FLGYTPDHWC
60 70 80 90 100
KTASLQEKCG FSEEQVRDLT VPRTGARGAF SKCVKFDDAL RNGSALSCNI
110 120 130 140 150
SIFNNSTHLS ACNEGWTFNE NRTTIVTEFS LVCEDSWLAD LNQVSLAGGF
160 170 180 190 200
FIGALVTGYL ADRFGRKSCF IASIFGLGVS GTCIIFSPYY PLLLFFRCLQ
210 220 230 240 250
GFFAKGAWTA TYVLIIEFFG SNNRKFVSVM SRTFYSLGLV LLPALAYYIP
260 270 280 290 300
SWRNLQLAMT LPTFIFLIYH WVIPESPRWL LSQRKTKEAL SIVKSIAKCN
310 320 330 340 350
KRSLPEDFHE MDLLIEKQEE IMRPSYKDLF KTPKMRKHTF ILIYAWFTGA
360 370 380 390 400
VVFQGLVLRL GITGDNVFLD FLISAVVELP TGLIFYFLVD RIGRRPLMAT
410 420 430 440 450
VNFIGGAACL AVPFISPNIS WLRRTIAIVG RLAVAIGNET VNFANTELYP
460 470 480 490 500
TPLRNLGVSV CSSASDIGAV VAPFILYRLA SIWQELPLLV YGVMSVLYSG
510 520 530 540 550
LVMLLPEMKG VDLPETVDDV ENLRSRHKRK EKDGAQFPEI NIVPMKAVEK
TSQK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX000363 Genomic DNA No translation available. CU462872 Genomic DNA No translation available. BC155336 mRNA Translation: AAI55337.1 |
RefSeqi | NP_001107932.1, NM_001114460.1 |
Genome annotation databases
Ensembli | ENSDART00000081707; ENSDARP00000076146; ENSDARG00000058775 |
GeneIDi | 797890 |
KEGGi | dre:797890 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX000363 Genomic DNA No translation available. CU462872 Genomic DNA No translation available. BC155336 mRNA Translation: AAI55337.1 |
RefSeqi | NP_001107932.1, NM_001114460.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000076146 |
Genome annotation databases
Ensembli | ENSDART00000081707; ENSDARP00000076146; ENSDARG00000058775 |
GeneIDi | 797890 |
KEGGi | dre:797890 |
Organism-specific databases
CTDi | 797890 |
ZFINi | ZDB-GENE-080204-92, oct2 |
Phylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00940000155089 |
HOGENOMi | CLU_001265_33_5_1 |
OMAi | FAKGAWT |
OrthoDBi | 762280at2759 |
TreeFami | TF315847 |
Enzyme and pathway databases
Reactomei | R-DRE-2161517, Abacavir transmembrane transport R-DRE-549127, Organic cation transport |
Gene expression databases
Bgeei | ENSDARG00000058775, Expressed in muscle organ and 20 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A9JTH0_DANRE | |
Accessioni | A9JTH0Primary (citable) accession number: A9JTH0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 5, 2008 |
Last sequence update: | February 5, 2008 | |
Last modified: | December 2, 2020 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |