Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kinesin-like protein

Gene

kif2c

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi346 – 353ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-DRE-2467813 Separation of Sister Chromatids
R-DRE-2500257 Resolution of Sister Chromatid Cohesion
R-DRE-5663220 RHO GTPases Activate Formins
R-DRE-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-DRE-68877 Mitotic Prometaphase
R-DRE-983189 Kinesins

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:kif2cImported
Synonyms:si:ch211-61f14.1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-070912-298 kif2c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleUniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000076228

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini256 – 586Kinesin motorInterPro annotationAdd BLAST331

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili664 – 684Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0246 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00920000148953
HOGENOMiHOG000231329
HOVERGENiHBG003875
KOiK10393
OMAiSTAMVEW

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9JRA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPALSKLLI GLAVNISRSD GRIHSAIVKT ANVSKSTVNV EWAEHGMTKG
60 70 80 90 100
KEVDMNELNH LNSDLIQHLQ PCHQEEPAPT PIPTPMTRMT KSVKASELPL
110 120 130 140 150
RSSRIPTTSE PSRRMTTRQT CLFRQPAPPP VVSASSADDV LSQNLPSSTI
160 170 180 190 200
PKHSGYQRRL LSKPASPLLP STEAICESEA SKCAPMGPPS HRMSQVSETN
210 220 230 240 250
KVANKRLSIA KMPDAQKRGK FGETNRSKQF YQMIEEYRET VQKVPMSLSD
260 270 280 290 300
PVKTHRICVC VRKRPLNKKE LAKKEIDVVT IPGNGVLLLH EPKQKVDLTK
310 320 330 340 350
YLENQTFHFD YSFDEDATND LVYRFTAKPL VKTIFEGGMA TCFAYGQTGS
360 370 380 390 400
GKTHTMGGDF SGKSQNSSKG IYALAAQDVF TLLRQKRYVD MDLCPYVTFF
410 420 430 440 450
EIYNGKVFDL LNKKTKLRVL EDEKQQVNVV GLQEVPVSCV DDVIKMIERG
460 470 480 490 500
SACRTSGQTF ANASSSRSHA ILQVILRRRN FLYGKFSLVD LAGNERGTDV
510 520 530 540 550
SSNDRHTIVE TAEINRSLLA LKECIRSLGQ NSEHIPFRMS KLTQVLRDSF
560 570 580 590 600
IGENSRTCMI AMISPGMSSC EYTLNTLRYA NRVKELNGIS KGDAVENGSK
610 620 630 640 650
LELSEEGNSS EEETVLPEFE AISRVSEMEE RFYEELKGCS EVAKSMELPS
660 670 680
FDIVANLSNI DSFMRKLQES YQALRSAIEA EQRVRMSPN
Length:689
Mass (Da):76,976
Last modified:February 5, 2008 - v1
Checksum:iC463401CEE870896
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX664751 Genomic DNA No translation available.
BC155585 mRNA Translation: AAI55586.1
RefSeqiNP_001108065.1, NM_001114593.1
UniGeneiDr.78383

Genome annotation databases

EnsembliENSDART00000111430; ENSDARP00000099090; ENSDARG00000076228
GeneIDi100136875
KEGGidre:100136875

Similar proteinsi

Entry informationi

Entry nameiA9JRA8_DANRE
AccessioniPrimary (citable) accession number: A9JRA8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: June 20, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health