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UniProtKB - A8XLW0 (GOSR1_CAEBR)
Protein
Golgi SNAP receptor complex member 1
Gene
gos-28
Organism
Caenorhabditis briggsae
Status
Functioni
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. Cooperates with ykt-6 for proper expression of Golgi-resident proteins. Required along with ykt-6 for normal embryonic development, seam cell division or differentiation, and ray formation (By similarity).
By similarityGO - Molecular functioni
- SNAP receptor activity Source: GO_Central
GO - Biological processi
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
- protein transport Source: UniProtKB-KW
- vesicle fusion Source: GO_Central
Keywordsi
Molecular function | Receptor |
Biological process | ER-Golgi transport, Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Golgi SNAP receptor complex member 1By similarityAlternative name(s): 28 kDa Golgi SNARE proteinBy similarity Short name: GOS-28By similarity |
Gene namesi | Name:gos-28Imported Synonyms:gosr-1By similarity, gs28By similarity ORF Names:CBG15298 |
Organismi | Caenorhabditis briggsae |
Taxonomic identifieri | 6238 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | CBG15298 ; CBP03713 ; WBGene00035605 ; Cbr-gos-28 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Single-pass type IV membrane protein By similarity
Golgi apparatus
- cis-Golgi network Source: GO_Central
- Golgi medial cisterna Source: GO_Central
- Golgi membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
- SNARE complex Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 212 | CytoplasmicSequence analysisBy similarityAdd BLAST | 212 | |
Transmembranei | 213 – 233 | Helical; Anchor for type IV membrane proteinSequence analysisBy similarityAdd BLAST | 21 | |
Topological domaini | 234 | VesicularSequence analysisBy similarity | 1 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000415756 | 1 – 234 | Golgi SNAP receptor complex member 1Add BLAST | 234 |
Interactioni
Subunit structurei
Component of several multiprotein Golgi SNARE complexes.
By similarityProtein-protein interaction databases
STRINGi | 6238.CBG15298 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 54 – 121 | Sequence analysisBy similarityAdd BLAST | 68 |
Sequence similaritiesi
Belongs to the GOSR1 family.Sequence analysis
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3208, Eukaryota |
HOGENOMi | CLU_078034_0_1_1 |
InParanoidi | A8XLW0 |
OMAi | QAYAVND |
OrthoDBi | 1319902at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR023601, Golgi_SNAP_su1 |
PANTHERi | PTHR21094, PTHR21094, 1 hit |
PIRSFi | PIRSF027109, Golgi_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
A8XLW0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSETWEALRK KARSTENSID VKLVSLNKLT ASSHGGFDID EKTVSSRQTT
60 70 80 90 100
FRTVTTEIEG LIEQLTNIND DMNDVAGAQS SASWASNPAI QHTLRRHREI
110 120 130 140 150
LRDYGSEYRR ARDNVDQVLQ RELLLSSSNN ESRNPAVNNR ARGYDMYLKE
160 170 180 190 200
NDHINACDRL LDEQIEMAMS TKENVARQGI NLRGISNRLH YITKKYPAIN
210 220 230
NLMQKIKTKK QKNTMILAGV ISACLIFTIF WIIN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HE601407 Genomic DNA Translation: CAP33635.1 |
RefSeqi | XP_002643125.1, XM_002643079.1 |
Genome annotation databases
EnsemblMetazoai | CBG15298.1; CBG15298.1; WBGene00035605 |
GeneIDi | 8585119 |
KEGGi | cbr:CBG15298 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HE601407 Genomic DNA Translation: CAP33635.1 |
RefSeqi | XP_002643125.1, XM_002643079.1 |
3D structure databases
SMRi | A8XLW0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 6238.CBG15298 |
Genome annotation databases
EnsemblMetazoai | CBG15298.1; CBG15298.1; WBGene00035605 |
GeneIDi | 8585119 |
KEGGi | cbr:CBG15298 |
Organism-specific databases
CTDi | 8585119 |
WormBasei | CBG15298 ; CBP03713 ; WBGene00035605 ; Cbr-gos-28 |
Phylogenomic databases
eggNOGi | KOG3208, Eukaryota |
HOGENOMi | CLU_078034_0_1_1 |
InParanoidi | A8XLW0 |
OMAi | QAYAVND |
OrthoDBi | 1319902at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR023601, Golgi_SNAP_su1 |
PANTHERi | PTHR21094, PTHR21094, 1 hit |
PIRSFi | PIRSF027109, Golgi_SNARE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GOSR1_CAEBR | |
Accessioni | A8XLW0Primary (citable) accession number: A8XLW0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 22, 2012 |
Last sequence update: | January 15, 2008 | |
Last modified: | February 23, 2022 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Caenorhabditis annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families