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Protein
Submitted name:

Tumor necrosis factor receptor superfamily, member 18

Gene

TNFRSF18

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor superfamily, member 18Imported
Gene namesi
Name:TNFRSF18Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei163 – 190HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500273173126 – 242Sequence analysisAdd BLAST217

Structurei

3D structure databases

SMRiA8WFP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 153TNFR-CysInterPro annotationAdd BLAST39

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J0PX Eukaryota
ENOG410YX1D LUCA
HOGENOMiHOG000049078
HOVERGENiHBG054195

Family and domain databases

CDDicd13417 TNFRSF18, 1 hit
InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022318 TNFR_18
IPR034018 TNFRSF18_N
PRINTSiPR01968 TNFACTORR18
SMARTiView protein in SMART
SM00208 TNFR, 1 hit

Sequencei

Sequence statusi: Fragment.

A8WFP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQHGAMGAF RALCGLALLC ALSLGQRPTG GPGCGPGRLL LGTGTDARCC
60 70 80 90 100
RVHTTRCCRD YPGEECCSEW DCMCVQPEFH CGDPCCTTCR HHPCPPGQGV
110 120 130 140 150
QSQGKFSFGF QCIDCASGTF SGGHEGHCKP WTDCTQFGFL TVFPGNKTHN
160 170 180 190 200
AVCVPGSPPA EPLGWLTVVL LAVAACVLLL TSAQLGLHIW QLRSQCMWPR
210 220 230 240
ETQLLLEVPP STEDARSCQF PEEERGERSA EEKGRLGDLW VL
Length:242
Mass (Da):26,113
Last modified:January 15, 2008 - v1
Checksum:i9AF0DC3B4AA7E82C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei242Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC152386 mRNA Translation: AAI52387.1
UniGeneiHs.212680

Similar proteinsi

Entry informationi

Entry nameiA8WFP4_HUMAN
AccessioniPrimary (citable) accession number: A8WFP4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 31, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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