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Entry version 80 (08 May 2019)
Sequence version 1 (15 Jan 2008)
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Protein

Ankyrin repeat and LEM domain-containing protein 1

Gene

Ankle1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Endonuclease that probably plays a role in the DNA damage response and DNA repair.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processDNA damage, DNA repair

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat and LEM domain-containing protein 1By similarity (EC:3.1.-.-By similarity)
Alternative name(s):
Ankyrin repeat domain-containing protein 41By similarity
LEM-domain containing protein 3By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ankle1Imported
Synonyms:Ankrd41Imported, Lem3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1918775 Ankle1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible phenotype. No defect in T cell, B cell and erythrocyte development. Normal percentage of common myeloid precursors (CMP) and common lymphoid precursors (CLP) in the bone marrow.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004381461 – 534Ankyrin repeat and LEM domain-containing protein 1CuratedAdd BLAST534

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8VU90

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8VU90

PRoteomics IDEntifications database

More...
PRIDEi
A8VU90

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8VU90

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Predominantly expressed in bone marrow, spleen, thymus, colon and ovary. Expressed also to a lesser extent in lymph nodes, liver and testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000046295 Expressed in 90 organ(s), highest expression level in bone marrow

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via LEM domain) with BANF1; the interaction may favor BANF1 dimerization.By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000113162

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A8VU90

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati4 – 35ANK 1Sequence analysisAdd BLAST32
Repeati39 – 71ANK 2Sequence analysisAdd BLAST33
Repeati75 – 104ANK 3Sequence analysisAdd BLAST30
Repeati108 – 137ANK 4Sequence analysisAdd BLAST30
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini279 – 323LEMPROSITE-ProRule annotationAdd BLAST45
Domaini370 – 485GIY-YIGPROSITE-ProRule annotationAdd BLAST116

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi498 – 505Nuclear localization signalBy similarity8

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The LEM domain is required for GIY-YIG domain-mediated DNA cleavage and induction of DNA damage response.By similarity

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEED Eukaryota
ENOG41104HP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000049316

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000015588

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8VU90

KEGG Orthology (KO)

More...
KOi
K21411

Identification of Orthologs from Complete Genome Data

More...
OMAi
QQGHLEC

Database of Orthologous Groups

More...
OrthoDBi
1451150at2759

TreeFam database of animal gene trees

More...
TreeFami
TF319333

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.720.40, 1 hit
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034998 ANKLE1
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000305 GIY-YIG_endonuc
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom

The PANTHER Classification System

More...
PANTHERi
PTHR46427 PTHR46427, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit
PF03020 LEM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit
SSF63451 SSF63451, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits
PS50164 GIY_YIG, 1 hit
PS50954 LEM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1Imported (identifier: A8VU90-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADTACLALR LLAALREEEA RAVEELLRLG ADPNLVLDDG AAAVHLAARA
60 70 80 90 100
SHPRALHCLR MLLRWGADPN ARSAEGLTPV HVAAAWGCCG ALELLLSRGG
110 120 130 140 150
DPTLRDQDGL RPLDWALQQR HHNCARVLQE LDTPTQPDET REPTETFHVA
160 170 180 190 200
QGSFETETCQ GPALAESSGV SQDSELHVHR AELEVEAVEV AVHPQSSEAT
210 220 230 240 250
ENSDYSSDAS FVTAVEDSLQ PGRPGGALEL VAGLWVTRGA VSAGKGAPNC
260 270 280 290 300
QPQVLTLTAR DTDKPVLPGD GDLGALHPHS SVPPMSDLQL LQALRALGYS
310 320 330 340 350
PGPVTPFTRG HYLRRLQEAQ ASRADVGHSQ ELAEALRTGT IPDCQVDEEA
360 370 380 390 400
LAQCFQRLDP LKKWREGITK SSFTYLLLDP RLTKDLPARA SSLTLAECLQ
410 420 430 440 450
CFVRAIFYVG KGTRARPDAH LWEAFGYHDQ PRKQVCPKVR RILDIWASGR
460 470 480 490 500
GIISLHCFQH VVAMEAYTRE ACLLDALGLQ TLTNQKQGHY YGVVAHWPPS
510 520 530
RRRRLGVHLL QRALLVFLAE GERELRPQDI QARG
Length:534
Mass (Da):58,441
Last modified:January 15, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i85D85E2D732FA96E
GO
Isoform 2Imported (identifier: A8VU90-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     145-164: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:514
Mass (Da):56,307
Checksum:i6F541592189461E8
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH30436 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAC38015 differs from that shown. Intron retention.Curated
The sequence BAC38015 differs from that shown. Reason: Frameshift at position 130.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti425F → L in AAH30436 (PubMed:15489334).Curated1
Sequence conflicti425F → L in AAI45660 (PubMed:15489334).Curated1
Sequence conflicti478 – 479GL → VF in BAC38015 (PubMed:16141072).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_058615145 – 164Missing in isoform 2. CuratedAdd BLAST20

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU184014 mRNA Translation: ABW73566.1
AK080768 mRNA Translation: BAC38015.1 Sequence problems.
AC127416 Genomic DNA No translation available.
CH466569 Genomic DNA Translation: EDL28917.1
CH466569 Genomic DNA Translation: EDL28919.1
BC030436 mRNA Translation: AAH30436.1 Different initiation.
BC145659 mRNA Translation: AAI45660.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS52583.1 [A8VU90-1]
CCDS80893.1 [A8VU90-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001297431.1, NM_001310502.1 [A8VU90-2]
NP_766344.2, NM_172756.3 [A8VU90-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000119976; ENSMUSP00000113162; ENSMUSG00000046295 [A8VU90-1]
ENSMUST00000120725; ENSMUSP00000112797; ENSMUSG00000046295 [A8VU90-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
234396

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:234396

UCSC genome browser

More...
UCSCi
uc009mdc.2 mouse
uc009mdd.2 mouse [A8VU90-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU184014 mRNA Translation: ABW73566.1
AK080768 mRNA Translation: BAC38015.1 Sequence problems.
AC127416 Genomic DNA No translation available.
CH466569 Genomic DNA Translation: EDL28917.1
CH466569 Genomic DNA Translation: EDL28919.1
BC030436 mRNA Translation: AAH30436.1 Different initiation.
BC145659 mRNA Translation: AAI45660.1
CCDSiCCDS52583.1 [A8VU90-1]
CCDS80893.1 [A8VU90-2]
RefSeqiNP_001297431.1, NM_001310502.1 [A8VU90-2]
NP_766344.2, NM_172756.3 [A8VU90-1]

3D structure databases

SMRiA8VU90
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113162

PTM databases

PhosphoSitePlusiA8VU90

Proteomic databases

MaxQBiA8VU90
PaxDbiA8VU90
PRIDEiA8VU90

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000119976; ENSMUSP00000113162; ENSMUSG00000046295 [A8VU90-1]
ENSMUST00000120725; ENSMUSP00000112797; ENSMUSG00000046295 [A8VU90-2]
GeneIDi234396
KEGGimmu:234396
UCSCiuc009mdc.2 mouse
uc009mdd.2 mouse [A8VU90-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
126549
MGIiMGI:1918775 Ankle1

Phylogenomic databases

eggNOGiENOG410IEED Eukaryota
ENOG41104HP LUCA
GeneTreeiENSGT00510000049316
HOGENOMiHOG000015588
InParanoidiA8VU90
KOiK21411
OMAiQQGHLEC
OrthoDBi1451150at2759
TreeFamiTF319333

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A8VU90

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000046295 Expressed in 90 organ(s), highest expression level in bone marrow

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.10.720.40, 1 hit
1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR034998 ANKLE1
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000305 GIY-YIG_endonuc
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
PANTHERiPTHR46427 PTHR46427, 2 hits
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF03020 LEM, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 4 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF63451 SSF63451, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits
PS50164 GIY_YIG, 1 hit
PS50954 LEM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANKL1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8VU90
Secondary accession number(s): A6H5W1
, G5E8T1, Q8C4V5, Q8K2N6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2016
Last sequence update: January 15, 2008
Last modified: May 8, 2019
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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