Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Malto-oligosyltrehalose trehalohydrolase

Gene

treZ

Organism
Actinoplanes sp. SN223/29
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)-alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D-glucan.UniRule annotation

Pathwayi: trehalose biosynthesis

This protein is involved in the pathway trehalose biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway trehalose biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei244NucleophileUniRule annotation1
Active sitei281Proton donorUniRule annotation1
Sitei377Transition state stabilizerUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

UniPathwayi
UPA00299

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
Malto-oligosyltrehalose trehalohydrolaseUniRule annotation (EC:3.2.1.141UniRule annotation)
Short name:
MTHaseUniRule annotation
Alternative name(s):
4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolaseUniRule annotation
Maltooligosyl trehalose trehalohydrolaseUniRule annotation
Gene namesi
Name:treZImported
OrganismiActinoplanes sp. SN223/29Imported
Taxonomic identifieri442459 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeActinoplanes

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

ProteinModelPortaliA8QX08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 496AamyInterPro annotationAdd BLAST398

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR022567 DUF3459
IPR006047 Glyco_hydro_13_cat_dom
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR012768 Trehalose_TreZ
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF11941 DUF3459, 1 hit
PIRSFiPIRSF006337 Trehalose_TreZ, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR02402 trehalose_TreZ, 1 hit

Sequencei

Sequence statusi: Complete.

A8QX08-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTFEVWAPE KSPKLRLDDQ EHEMEPGDGG WWRLDVPTAG PGTDYAYVLE
60 70 80 90 100
DVAAPVPDPR SAWQPQGVHG PSRVYDHAAF TWTDQRWPGR QLPGAVLYEL
110 120 130 140 150
HIGTFTPAGT FDAAIERLDH LVDLGVDLVE LLPVNAFNGE HNWGYDGVCW
160 170 180 190 200
YAPHEAYGGP DGLKRFVDAA HAKGLGVVLD VVYNHFGPSG AYAPMFAPYL
210 220 230 240 250
SAGQNTWGSS LNLDGPDSGE VRRYIADSVL MWLRDYHIDG LRLDAVHALH
260 270 280 290 300
DEGAVHLLEQ LAVEVESLST ALRRPLTLIA ESDLNDPKLI TPREAGGYGL
310 320 330 340 350
HAQWDDDVHH ALHSLLTGER QGYYGDFGSL DCLRTVLEGA FYHAGTWSSF
360 370 380 390 400
RNRRHGRPVD RQRTAGHRFV AFLQNHDQIG NRAIGDRLTA TLSPGLLKVG
410 420 430 440 450
ATLLLTSPFT PMLFMGEEWA ASSPWQFFTS HPEPELAAAV QTGRRREFAR
460 470 480 490 500
HGWAEADVPD PQDPATFQRS KLDWSELGKP EHAEMLALYK KLIRLRREVP
510 520 530 540 550
DLTDPWLSEV EVWHGDQFVV IRRGRHAVAA NLAETPQTVS LRAVPSAVLL
560 570
ATADGVILER DRVVLPPESA VVVRTSR
Length:577
Mass (Da):64,098
Last modified:January 15, 2008 - v1
Checksum:iAB01264076EFE87A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF364111 Genomic DNA Translation: ABV26726.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF364111 Genomic DNA Translation: ABV26726.1

3D structure databases

ProteinModelPortaliA8QX08
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00299

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR022567 DUF3459
IPR006047 Glyco_hydro_13_cat_dom
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR012768 Trehalose_TreZ
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF11941 DUF3459, 1 hit
PIRSFiPIRSF006337 Trehalose_TreZ, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR02402 trehalose_TreZ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA8QX08_9ACTN
AccessioniPrimary (citable) accession number: A8QX08
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: September 12, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again