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Protein

Envoplakin-like protein

Gene

EVPLL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Envoplakin-like protein
Gene namesi
Name:EVPLL
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000214860.4
HGNCiHGNC:35236 EVPLL
neXtProtiNX_A8MZ36

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000214860
PharmGKBiPA164719396

Polymorphism and mutation databases

BioMutaiEVPLL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003953231 – 301Envoplakin-like proteinAdd BLAST301

Proteomic databases

MaxQBiA8MZ36
PaxDbiA8MZ36
PRIDEiA8MZ36
ProteomicsDBi2451

Expressioni

Gene expression databases

BgeeiENSG00000214860
GenevisibleiA8MZ36 HS

Organism-specific databases

HPAiHPA045728

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000382086

Structurei

3D structure databases

ProteinModelPortaliA8MZ36
SMRiA8MZ36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 88Sequence analysisAdd BLAST88

Sequence similaritiesi

Belongs to the plakin or cytolinker family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0516 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000119163
HOGENOMiHOG000015405
HOVERGENiHBG103026
InParanoidiA8MZ36
OMAiKMVLPPR
OrthoDBiEOG091G0G83
PhylomeDBiA8MZ36

Family and domain databases

InterProiView protein in InterPro
IPR030460 Envoplakin
PANTHERiPTHR23169:SF7 PTHR23169:SF7, 2 hits

Sequencei

Sequence statusi: Complete.

A8MZ36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQASADQVER DILETQKRLQ QDRLNSEQSQ ALQHQQETGS SLKEAEVLLK
60 70 80 90 100
DLFLDVDKAR RLKHPQAEET EKDIEQLHER VTQECAEYCA LYEKMVLPPR
110 120 130 140 150
RGIQGRLGTR AGAETEAGLR RPVWAGHGGA GGTDRGAQHR AEGDQRPRRA
160 170 180 190 200
AAEPGGAGCR HHPEPIPRPT EGGVVARAEP GQPVHALQGC TWQLSALAEQ
210 220 230 240 250
QRRILQQDWS DLMADPAGVR REYEHFKQHE LLSQEQSVNQ LEEDGKRMVE
260 270 280 290 300
LRHPAVGPIQ AHQEALKMEW QNFLNLCICQ ETQLQHVEDY SRILCPSSSP

H
Length:301
Mass (Da):33,953
Last modified:December 4, 2007 - v1
Checksum:i704AB98521CE2028
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0633994S → N1 PublicationCorresponds to variant dbSNP:rs570145Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298286 mRNA Translation: BAG60546.1
AL353997 Genomic DNA No translation available.
BC026998 mRNA No translation available.
BC036791 mRNA No translation available.
CCDSiCCDS45626.1
RefSeqiNP_001138599.1, NM_001145127.1
UniGeneiHs.462400

Genome annotation databases

EnsembliENST00000399134; ENSP00000382086; ENSG00000214860
ENST00000640722; ENSP00000492399; ENSG00000284166
GeneIDi645027
KEGGihsa:645027
UCSCiuc002gte.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiEVPLL_HUMAN
AccessioniPrimary (citable) accession number: A8MZ36
Secondary accession number(s): B4DPD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: December 4, 2007
Last modified: July 18, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

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