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UniProtKB - A8MYJ1 (A8MYJ1_HUMAN)

Entry version 121 (02 Dec 2020)
Sequence version 3 (29 Oct 2014)
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Protein
Submitted name:

A-kinase anchor protein 13

Gene

AKAP13

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factorARBA annotation
LigandZincARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
A-kinase anchor protein 13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AKAP13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000170776.19

Human Gene Nomenclature Database

More...HGNCi		HGNC:371, AKAP13

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000170776

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA24665

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...PeptideAtlasi		A8MYJ1

PRoteomics IDEntifications database

More...PRIDEi		A8MYJ1

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		2405

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000170776, Expressed in tendon of biceps brachii and 252 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A8MYJ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A8MYJ1, HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini413 – 460Phorbol-ester/DAG-typeInterPro annotationAdd BLAST48
Domaini615 – 812DHInterPro annotationAdd BLAST198
Domaini852 – 954PHInterPro annotationAdd BLAST103

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni71 – 90DisorderedSequence analysisAdd BLAST20
Regioni107 – 183DisorderedSequence analysisAdd BLAST77
Regioni229 – 270DisorderedSequence analysisAdd BLAST42
Regioni377 – 415DisorderedSequence analysisAdd BLAST39
Regioni1087 – 1123DisorderedSequence analysisAdd BLAST37
Regioni1286 – 1434DisorderedSequence analysisAdd BLAST149

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili972 – 999Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi71 – 87PolyampholyteSequence analysisAdd BLAST17
Compositional biasi107 – 141PolarSequence analysisAdd BLAST35
Compositional biasi253 – 270PolyampholyteSequence analysisAdd BLAST18
Compositional biasi379 – 412PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1099 – 1122PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1286 – 1310PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1334 – 1353PolarSequence analysisAdd BLAST20
Compositional biasi1365 – 1395PolarSequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154146

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002466_1_0_1

Family and domain databases

Conserved Domains Database

More...CDDi		cd00160, RhoGEF, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.900.10, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR028852, AKAP13
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR002219, PE/DAG-bd
IPR011993, PH-like_dom_sf
IPR041020, PH_16
IPR001849, PH_domain

The PANTHER Classification System

More...PANTHERi		PTHR13944:SF18, PTHR13944:SF18, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17838, PH_16, 1 hit
PF00621, RhoGEF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00109, C1, 1 hit
SM00233, PH, 1 hit
SM00325, RhoGEF, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48065, SSF48065, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50010, DH_2, 1 hit
PS50003, PH_DOMAIN, 1 hit
PS00479, ZF_DAG_PE_1, 1 hit
PS50081, ZF_DAG_PE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

A8MYJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYERHKRRYS LCDISKVDRT VDVVLLKINR ENWCTIEPCP DAASLLASKQ 
        60         70         80         90        100
SPECENFLDV GLGRECTSKQ GVLKRESGSD SDLFHSPSDD MDSIIFPKPE 
       110        120        130        140        150
EEHLACDITG SSSSTDDTAS LDRHSSHGSD VSLSQILKPN RSRDRQSLDG 
       160        170        180        190        200
FYSHGMGAEG RESESEPADP GDVEEEEMDS ITEVPANCSV LRSSMRSLSP 
       210        220        230        240        250
FRRHSWGPGK NAASDAEMNH RSFSLEGLTG GAGVGNKPSS SLEVSSANAE 
       260        270        280        290        300
ELRHPFSGEE RVDSLVSLSE EDLESDQREH RMFDQQICHR SKQQGFNYCT 
       310        320        330        340        350
SAISSPLTKS ISLMTISHPG LDNSRPFHST FHNTSANLTE SITEENYNFL 
       360        370        380        390        400
PHSPSKKDSE WKSGTKVSRT FSYIKNKMSS SKKSKEKEKE KDKIKEKEKD 
       410        420        430        440        450
SKDKEKDKKT VNGHTFSSIP VVGPISCSQC MKPFTNKDAY TCANCSAFVH 
       460        470        480        490        500
KGCRESLASC AKVKMKPKGS LQAHDTSSLP TVIMRNKPSQ PKERPRSAVL 
       510        520        530        540        550
LVDETATTPI FANRRSQQSV SLSKSVSIQN ITGVGNDENM SNTWKFLSHS 
       560        570        580        590        600
TDSLNKISKV NESTESLTDE GVGTDMNEGQ LLGDFEIESK QLEAESWSRI 
       610        620        630        640        650
IDSKFLKQQK KDVVKRQEVI YELMQTEFHH VRTLKIMSGV YSQGMMADLL 
       660        670        680        690        700
FEQQMVEKLF PCLDELISIH SQFFQRILER KKESLVDKSE KNFLIKRIGD 
       710        720        730        740        750
VLVNQFSGEN AERLKKTYGK FCGQHNQSVN YFKDLYAKDK RFQAFVKKKM 
       760        770        780        790        800
SSSVVRRLGI PECILLVTQR ITKYPVLFQR ILQCTKDNEV EQEDLAQSLS 
       810        820        830        840        850
LVKDVIGAVD SKVASYEKKV RLNEIYTKTD SKSIMRMKSG QMFAKEDLKR 
       860        870        880        890        900
KKLVRDGSVF LKNAAGRLKE VQAVLLTDIL VFLQEKDQKY IFASLDQKST 
       910        920        930        940        950
VISLKKLIVR EVAHEEKGLF LISMGMTDPE MVEVHASSKE ERNSWIQIIQ 
       960        970        980        990       1000
DTINTLNRDE DEGIPSENEE EKKMLDTRAR ELKEQLHQKD QKILLLLEEK 
      1010       1020       1030       1040       1050
EMIFRDMAEC STPLPEDCSP THSPRVLFRS NTEEALKGGP LMKSAINEVE 
      1060       1070       1080       1090       1100
ILQGLVSGNL GGTLGPTVSS PIEQDVVGPV SLPRRAETFG GFDSHQMNAS 
      1110       1120       1130       1140       1150
KGGEKEEGDD GQDLRRTESD SGLKKGGNAN LVFMLKRNSE QVVQSVVHLY 
      1160       1170       1180       1190       1200
ELLSALQGVV LQQDSYIEDQ KLVLSERALT RSLSRPSSLI EQEKQRSLEK 
      1210       1220       1230       1240       1250
QRQDLANLQK QQAQYLEEKR RREREWEARE RELREREALL AQREEEVQQG 
      1260       1270       1280       1290       1300
QQDLEKEREE LQQKKGTYQY DLERLRAAQK QLEREQEQLR REAERLSQRQ 
      1310       1320       1330       1340       1350
TERDLCQVSH PHTKLMRIPS FFPSPEEPPS PSAPSIAKSG SLDSELSVSP 
      1360       1370       1380       1390       1400
KRNSISRTHK DKGPFHILSS TSQTNKGPEG QSQAPASTSA STRLFGLTKP 
      1410       1420       1430 
KEKKEKKKKN KTSRSQPGDG PASEVSAEGE EIFC
Length:1,434
Mass (Da):161,841
Last modified:October 29, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE181F9F0421C7CC6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q12802AKP13_HUMAN
A-kinase anchor protein 13
AKAP13 BRX, HT31, LBC
2,813Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WTD7A0A087WTD7_HUMAN
A-kinase anchor protein 13
AKAP13
1,429Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WY36A0A087WY36_HUMAN
A-kinase anchor protein 13
AKAP13
967Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WX73A0A087WX73_HUMAN
A-kinase anchor protein 13
AKAP13
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YMW2H0YMW2_HUMAN
A-kinase anchor protein 13
AKAP13
1,745Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YLH1H0YLH1_HUMAN
A-kinase anchor protein 13
AKAP13
275Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YK84H0YK84_HUMAN
A-kinase anchor protein 13
AKAP13
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYS7A0A087WYS7_HUMAN
A-kinase anchor protein 13
AKAP13
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YK18H0YK18_HUMAN
A-kinase anchor protein 13
AKAP13
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YMI5H0YMI5_HUMAN
A-kinase anchor protein 13
AKAP13
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC021739 Genomic DNA No translation available.
AC087286 Genomic DNA No translation available.
AC104046 Genomic DNA No translation available.
AC110592 Genomic DNA No translation available.
KC877559 Genomic DNA No translation available.
KC877571 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001257475.1, NM_001270546.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000394510; ENSP00000378018; ENSG00000170776

Database of genes from NCBI RefSeq genomes

More...GeneIDi		11214

UCSC genome browser

More...UCSCi		uc031qtl.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021739 Genomic DNA No translation available.
AC087286 Genomic DNA No translation available.
AC104046 Genomic DNA No translation available.
AC110592 Genomic DNA No translation available.
KC877559 Genomic DNA No translation available.
KC877571 Genomic DNA No translation available.
RefSeqiNP_001257475.1, NM_001270546.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PeptideAtlasiA8MYJ1
PRIDEiA8MYJ1
ProteomicsDBi2405

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		15576, 187 antibodies

Genome annotation databases

EnsembliENST00000394510; ENSP00000378018; ENSG00000170776
GeneIDi11214
UCSCiuc031qtl.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11214
EuPathDBiHostDB:ENSG00000170776.19
HGNCiHGNC:371, AKAP13
OpenTargetsiENSG00000170776
PharmGKBiPA24665

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00940000154146
HOGENOMiCLU_002466_1_0_1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		11214, 9 hits in 848 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		AKAP13, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		11214

Gene expression databases

BgeeiENSG00000170776, Expressed in tendon of biceps brachii and 252 other tissues
ExpressionAtlasiA8MYJ1, baseline and differential
GenevisibleiA8MYJ1, HS

Family and domain databases

CDDicd00160, RhoGEF, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR028852, AKAP13
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR002219, PE/DAG-bd
IPR011993, PH-like_dom_sf
IPR041020, PH_16
IPR001849, PH_domain
PANTHERiPTHR13944:SF18, PTHR13944:SF18, 1 hit
PfamiView protein in Pfam
PF17838, PH_16, 1 hit
PF00621, RhoGEF, 1 hit
SMARTiView protein in SMART
SM00109, C1, 1 hit
SM00233, PH, 1 hit
SM00325, RhoGEF, 1 hit
SUPFAMiSSF48065, SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010, DH_2, 1 hit
PS50003, PH_DOMAIN, 1 hit
PS00479, ZF_DAG_PE_1, 1 hit
PS50081, ZF_DAG_PE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA8MYJ1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MYJ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: October 29, 2014
Last modified: December 2, 2020
This is version 121 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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