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Entry version 122 (29 Sep 2021)
Sequence version 3 (14 May 2014)
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Protein

Zinc finger protein 99

Gene

ZNF99

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri173 – 195C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 8; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri649 – 671C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri677 – 699C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri705 – 727C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri733 – 755C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri761 – 783C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri789 – 811C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri817 – 839C2H2-type 24PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A8MXY4

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 99
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF99
Synonyms:C19orf9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13175, ZNF99

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603981, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A8MXY4

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000213973

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7652

Open Targets

More...
OpenTargetsi
ENSG00000213973

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37747

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A8MXY4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF99

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004291271 – 864Zinc finger protein 99Add BLAST864

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A8MXY4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A8MXY4

PeptideAtlas

More...
PeptideAtlasi
A8MXY4

PRoteomics IDEntifications database

More...
PRIDEi
A8MXY4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
2362

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A8MXY4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8MXY4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000213973, Expressed in female gonad and 21 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A8MXY4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A8MXY4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000213973, Tissue enhanced (kidney, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
113467, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000472969

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A8MXY4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A8MXY4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 75KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri173 – 195C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 8; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri649 – 671C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri677 – 699C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri705 – 727C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri733 – 755C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri761 – 783C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri789 – 811C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri817 – 839C2H2-type 24PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163381

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8MXY4

Identification of Orthologs from Complete Genome Data

More...
OMAi
VIHMERN

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 19 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 23 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 13 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 21 hits
PS50157, ZINC_FINGER_C2H2_2, 24 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A8MXY4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSLTFWDVT IEFALEEWQC LDMAQQNLYR NVMLENYRNL VFLGIAVSKL
60 70 80 90 100
DLITCLKQGK EPWNMKRHEM VTKPPVISSH FTQDFWPDQS IKDSFQEIIL
110 120 130 140 150
RTYARCGHKN LRLRKDCESV NEGKMHEEAY NKLNQCWTTT QGKIFQCNKY
160 170 180 190 200
VKVFHKYSNS NRYKIRHTKK KTFKCMKCSK SFFMLSHLIQ HKRIHTRENI
210 220 230 240 250
YKCEERGKAF KWFSTLIKHK IIHTEDKPYK YKKCGKAFNI SSMFTKCKII
260 270 280 290 300
HTGKKPCKCE ECGKVFNNSS TLMKHKIIHT GKKPYKCEEC GKAFKQSSHL
310 320 330 340 350
TRHKAIHTGE KPYKCEECGK AFNHFSALRK HQIIHTGKKP YKCEECGKAF
360 370 380 390 400
SQSSTLRKHE IIHTEEKPYK YEECGKAFSN LSALRKHEII HTGQKPYKCE
410 420 430 440 450
ECGKAFKWSS KLTVHKVIHT AEKPCKCEEC GKAFKRFSAL RKHKIIHTGK
460 470 480 490 500
QPYKCEECSK AFSNFSALRK HEIIHTGEKP YKCEECGKAF KWSSKLTVHK
510 520 530 540 550
VIHMEEKPCK CEECGKAFKH FSALRKHKII HTGKKPYKCE ECGKAFNNSS
560 570 580 590 600
TLMKHKIIHT GKKPYKCEEC GKAFKQSSHL TRHKAIHTGE KPYKCEECGK
610 620 630 640 650
AFNHFSALRK HQIIHTGKKP YKCEECGKAF SQSSTLRKHE IIHTGEKPYK
660 670 680 690 700
CEECGKAFKW SSHLTRHKVI HTEEKPYKCE ECGKAFNHFS ALRKHKIIHT
710 720 730 740 750
GKKPYKCEEC GKAFSQSSTL RKHEIIHTGE KPYKCEECGK AFKWSSKLTV
760 770 780 790 800
HKVIHTAEKP CKCEECGKAF KHFSALRKHK IIHTGKKPYK CEECGKAFNN
810 820 830 840 850
SSTLRKHEII HTGEKSYKCE ECGKAFQWSS KLTLHKVIHM ERNPANVKNV
860
AKLLNISQPL ENMR
Length:864
Mass (Da):100,791
Last modified:May 14, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF66A625F51E5149
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MS76A0A0A0MS76_HUMAN
Zinc finger protein 99
ZNF99
1,037Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0619357W → R. Corresponds to variant dbSNP:rs34726149Ensembl.1
Natural variantiVAR_044501129A → G. Corresponds to variant dbSNP:rs7255780Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC008626 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS59369.1

NCBI Reference Sequences

More...
RefSeqi
NP_001073878.2, NM_001080409.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000596209; ENSP00000472969; ENSG00000213973

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7652

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7652

UCSC genome browser

More...
UCSCi
uc021urt.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008626 Genomic DNA No translation available.
CCDSiCCDS59369.1
RefSeqiNP_001073878.2, NM_001080409.2

3D structure databases

SMRiA8MXY4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113467, 2 interactors
STRINGi9606.ENSP00000472969

PTM databases

iPTMnetiA8MXY4
PhosphoSitePlusiA8MXY4

Genetic variation databases

BioMutaiZNF99

Proteomic databases

jPOSTiA8MXY4
MassIVEiA8MXY4
PeptideAtlasiA8MXY4
PRIDEiA8MXY4
ProteomicsDBi2362

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
56870, 57 antibodies

The DNASU plasmid repository

More...
DNASUi
7652

Genome annotation databases

EnsembliENST00000596209; ENSP00000472969; ENSG00000213973
GeneIDi7652
KEGGihsa:7652
UCSCiuc021urt.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7652
DisGeNETi7652

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF99
HGNCiHGNC:13175, ZNF99
HPAiENSG00000213973, Tissue enhanced (kidney, testis)
MIMi603981, gene
neXtProtiNX_A8MXY4
OpenTargetsiENSG00000213973
PharmGKBiPA37747
VEuPathDBiHostDB:ENSG00000213973

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000163381
InParanoidiA8MXY4
OMAiVIHMERN
OrthoDBi1318335at2759
TreeFamiTF343410

Enzyme and pathway databases

PathwayCommonsiA8MXY4
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
7652, 5 hits in 953 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7652
PharosiA8MXY4, Tdark

Protein Ontology

More...
PROi
PR:A8MXY4
RNActiA8MXY4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000213973, Expressed in female gonad and 21 other tissues
ExpressionAtlasiA8MXY4, baseline and differential
GenevisibleiA8MXY4, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 19 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 23 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 13 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 21 hits
PS50157, ZINC_FINGER_C2H2_2, 24 hits

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF99_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MXY4
Secondary accession number(s): M0R335
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 14, 2014
Last modified: September 29, 2021
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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