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Entry version 99 (08 May 2019)
Sequence version 2 (20 May 2008)
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Protein

UPF0577 protein KIAA1324-like

Gene

KIAA1324L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UPF0577 protein KIAA1324-like
Alternative name(s):
Estrogen-induced gene 121-like protein
Short name:
hEIG121L
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIAA1324L
Synonyms:EIG121L
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:21945 KIAA1324L

Online Mendelian Inheritance in Man (OMIM)

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MIMi
614048 gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_A8MWY0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini48 – 929ExtracellularSequence analysisAdd BLAST882
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei930 – 950HelicalSequence analysisAdd BLAST21
Topological domaini951 – 1029CytoplasmicSequence analysisAdd BLAST79

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000164659

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA142671608

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KIAA1324L

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 47Sequence analysisAdd BLAST47
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000033379848 – 1029UPF0577 protein KIAA1324-likeAdd BLAST982

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi293 ↔ 310By similarity
Disulfide bondi323 ↔ 346By similarity
Disulfide bondi326 ↔ 358By similarity
Glycosylationi405N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi691N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1018PhosphoserineCombined sources1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
A8MWY0

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
A8MWY0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8MWY0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8MWY0

PRoteomics IDEntifications database

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PRIDEi
A8MWY0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
2277
2278 [A8MWY0-2]
2279 [A8MWY0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A8MWY0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8MWY0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164659 Expressed in 187 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
A8MWY0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
A8MWY0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044527
HPA076093

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
128789, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000413445

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
A8MWY0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0577 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IR7A Eukaryota
ENOG410XVXU LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000154983

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006645

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
A8MWY0

Identification of Orthologs from Complete Genome Data

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OMAi
TECTFSC

Database of Orthologous Groups

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OrthoDBi
192139at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8MWY0

TreeFam database of animal gene trees

More...
TreeFami
TF315906

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR039181 EIG121-like
IPR009030 Growth_fac_rcpt_cys_sf
IPR011641 Tyr-kin_ephrin_A/B_rcpt-like

The PANTHER Classification System

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PANTHERi
PTHR22727 PTHR22727, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM01411 Ephrin_rec_like, 4 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF57184 SSF57184, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A8MWY0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLFRARGPVR GRGWGRPAEA PRRGRSPPWS PAWICCWALA GCQAAWAGDL
60 70 80 90 100
PSSSSRPLPP CQEKDYHFEY TECDSSGSRW RVAIPNSAVD CSGLPDPVRG
110 120 130 140 150
KECTFSCASG EYLEMKNQVC SKCGEGTYSL GSGIKFDEWD ELPAGFSNIA
160 170 180 190 200
TFMDTVVGPS DSRPDGCNNS SWIPRGNYIE SNRDDCTVSL IYAVHLKKSG
210 220 230 240 250
YVFFEYQYVD NNIFFEFFIQ NDQCQEMDTT TDKWVKLTDN GEWGSHSVML
260 270 280 290 300
KSGTNILYWR TTGILMGSKA VKPVLVKNIT IEGVAYTSEC FPCKPGTFSN
310 320 330 340 350
KPGSFNCQVC PRNTYSEKGA KECIRCKDDS QFSEEGSSEC TERPPCTTKD
360 370 380 390 400
YFQIHTPCDE EGKTQIMYKW IEPKICREDL TDAIRLPPSG EKKDCPPCNP
410 420 430 440 450
GFYNNGSSSC HPCPPGTFSD GTKECRPCPA GTEPALGFEY KWWNVLPGNM
460 470 480 490 500
KTSCFNVGNS KCDGMNGWEV AGDHIQSGAG GSDNDYLILN LHIPGFKPPT
510 520 530 540 550
SMTGATGSEL GRITFVFETL CSADCVLYFM VDINRKSTNV VESWGGTKEK
560 570 580 590 600
QAYTHIIFKN ATFTFTWAFQ RTNQGQDNRR FINDMVKIYS ITATNAVDGV
610 620 630 640 650
ASSCRACALG SEQSGSSCVP CPPGHYIEKE TNQCKECPPD TYLSIHQVYG
660 670 680 690 700
KEACIPCGPG SKNNQDHSVC YSDCFFYHEK ENQSLHYDFS NLSSVGSLMN
710 720 730 740 750
GPSFTSKGTK YFHFFNISLC GHEGKKMALC TNNITDFTVK EIVAGSDDYT
760 770 780 790 800
NLVGAFVCQS TIIPSESKGF RAALSSQSII LADTFIGVTV ETTLKNINIK
810 820 830 840 850
EDMFPVPTSQ IPDVHFFYKS STATTSCING RSTAVKMRCN PTKSGAGVIS
860 870 880 890 900
VPSKCPAGTC DGCTFYFLWE SAEACPLCTE HDFHEIEGAC KRGFQETLYV
910 920 930 940 950
WNEPKWCIKG ISLPEKKLAT CETVDFWLKV GAGVGAFTAV LLVALTCYFW
960 970 980 990 1000
KKNQKLEYKY SKLVMTTNSK ECELPAADSC AIMEGEDNEE EVVYSNKQSL
1010 1020
LGKLKSLATK EKEDHFESVQ LKTSRSPNI
Length:1,029
Mass (Da):113,842
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF7E919BAB202DAF
GO
Isoform 2 (identifier: A8MWY0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-240: Missing.
     241-247: GEWGSHS → MLEGNYQ

Note: No experimental confirmation available.
Show »
Length:789
Mass (Da):87,063
Checksum:i08BA2D080B8DAE64
GO
Isoform 3 (identifier: A8MWY0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-167: Missing.
     168-169: NN → MH

Note: No experimental confirmation available.
Show »
Length:862
Mass (Da):95,750
Checksum:i16E6507AA41EEDF9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JA41C9JA41_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
958Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C2N5H7C2N5_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
971Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JFK7C9JFK7_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1LLU5F1LLU5_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BYL8H7BYL8_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BZ34H7BZ34_HUMAN
UPF0577 protein KIAA1324-like
KIAA1324L
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI17310 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB71041 differs from that shown. Reason: Frameshift at position 719.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti678H → P in BAB71041 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_043161539N → Y. Corresponds to variant dbSNP:rs1029366Ensembl.1
Natural variantiVAR_043162729L → V. Corresponds to variant dbSNP:rs34412146Ensembl.1
Natural variantiVAR_043163767S → R. Corresponds to variant dbSNP:rs34577440Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0335291 – 240Missing in isoform 2. 1 PublicationAdd BLAST240
Alternative sequenceiVSP_0432541 – 167Missing in isoform 3. 1 PublicationAdd BLAST167
Alternative sequenceiVSP_043255168 – 169NN → MH in isoform 3. 1 Publication2
Alternative sequenceiVSP_033530241 – 247GEWGSHS → MLEGNYQ in isoform 2. 1 Publication7

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055902 mRNA Translation: BAB71041.1 Frameshift.
AK296250 mRNA Translation: BAG58965.1
AC000122 Genomic DNA No translation available.
AC002081 Genomic DNA No translation available.
AC004519 Genomic DNA No translation available.
CH236949 Genomic DNA Translation: EAL24181.1
CH471091 Genomic DNA Translation: EAW76969.1
BC117309 mRNA Translation: AAI17310.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34677.2 [A8MWY0-3]
CCDS47632.1 [A8MWY0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001136221.1, NM_001142749.2 [A8MWY0-1]
NP_001278920.1, NM_001291991.1 [A8MWY0-2]
NP_689961.3, NM_152748.3 [A8MWY0-3]
XP_016867333.1, XM_017011844.1 [A8MWY0-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000416314; ENSP00000402390; ENSG00000164659 [A8MWY0-3]
ENST00000450689; ENSP00000413445; ENSG00000164659 [A8MWY0-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
222223

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:222223

UCSC genome browser

More...
UCSCi
uc003uie.5 human [A8MWY0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055902 mRNA Translation: BAB71041.1 Frameshift.
AK296250 mRNA Translation: BAG58965.1
AC000122 Genomic DNA No translation available.
AC002081 Genomic DNA No translation available.
AC004519 Genomic DNA No translation available.
CH236949 Genomic DNA Translation: EAL24181.1
CH471091 Genomic DNA Translation: EAW76969.1
BC117309 mRNA Translation: AAI17310.1 Different initiation.
CCDSiCCDS34677.2 [A8MWY0-3]
CCDS47632.1 [A8MWY0-1]
RefSeqiNP_001136221.1, NM_001142749.2 [A8MWY0-1]
NP_001278920.1, NM_001291991.1 [A8MWY0-2]
NP_689961.3, NM_152748.3 [A8MWY0-3]
XP_016867333.1, XM_017011844.1 [A8MWY0-3]

3D structure databases

SMRiA8MWY0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128789, 3 interactors
STRINGi9606.ENSP00000413445

PTM databases

iPTMnetiA8MWY0
PhosphoSitePlusiA8MWY0

Polymorphism and mutation databases

BioMutaiKIAA1324L

Proteomic databases

EPDiA8MWY0
jPOSTiA8MWY0
MaxQBiA8MWY0
PaxDbiA8MWY0
PRIDEiA8MWY0
ProteomicsDBi2277
2278 [A8MWY0-2]
2279 [A8MWY0-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
222223
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000416314; ENSP00000402390; ENSG00000164659 [A8MWY0-3]
ENST00000450689; ENSP00000413445; ENSG00000164659 [A8MWY0-1]
GeneIDi222223
KEGGihsa:222223
UCSCiuc003uie.5 human [A8MWY0-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
222223

GeneCards: human genes, protein and diseases

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GeneCardsi
KIAA1324L
HGNCiHGNC:21945 KIAA1324L
HPAiHPA044527
HPA076093
MIMi614048 gene
neXtProtiNX_A8MWY0
OpenTargetsiENSG00000164659
PharmGKBiPA142671608

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IR7A Eukaryota
ENOG410XVXU LUCA
GeneTreeiENSGT00940000154983
HOGENOMiHOG000006645
InParanoidiA8MWY0
OMAiTECTFSC
OrthoDBi192139at2759
PhylomeDBiA8MWY0
TreeFamiTF315906

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
KIAA1324L human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
222223

Protein Ontology

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PROi
PR:A8MWY0

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000164659 Expressed in 187 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA8MWY0 baseline and differential
GenevisibleiA8MWY0 HS

Family and domain databases

InterProiView protein in InterPro
IPR039181 EIG121-like
IPR009030 Growth_fac_rcpt_cys_sf
IPR011641 Tyr-kin_ephrin_A/B_rcpt-like
PANTHERiPTHR22727 PTHR22727, 1 hit
SMARTiView protein in SMART
SM01411 Ephrin_rec_like, 4 hits
SUPFAMiSSF57184 SSF57184, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK132L_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MWY0
Secondary accession number(s): A4D1C9
, B4DJV3, Q17RI6, Q96DP2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 8, 2019
This is version 99 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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