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Entry version 94 (12 Aug 2020)
Sequence version 1 (04 Dec 2007)
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Protein

Protein FAM171A2

Gene

FAM171A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A8MVW0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM171A2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000161682.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30480, FAM171A2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A8MVW0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini30 – 315ExtracellularSequence analysisAdd BLAST286
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Topological domaini337 – 826CytoplasmicSequence analysisAdd BLAST490

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
284069

Open Targets

More...
OpenTargetsi
ENSG00000161682

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162387197

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A8MVW0, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM171A2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000032877130 – 826Protein FAM171A2Add BLAST797

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi66N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi201N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi221N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi265N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei370PhosphoserineBy similarity1
Modified residuei372PhosphoserineBy similarity1
Modified residuei789PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A8MVW0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A8MVW0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A8MVW0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8MVW0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8MVW0

PeptideAtlas

More...
PeptideAtlasi
A8MVW0

PRoteomics IDEntifications database

More...
PRIDEi
A8MVW0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
2208

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1658, 3 N-Linked glycans (2 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
A8MVW0, 4 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A8MVW0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8MVW0

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
A8MVW0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000161682, Expressed in cortical plate and 125 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A8MVW0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A8MVW0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000161682, Tissue enhanced (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
129748, 36 interactors

Protein interaction database and analysis system

More...
IntActi
A8MVW0, 18 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000293443

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A8MVW0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi474 – 480Poly-Pro7
Compositional biasi550 – 607Gly-richAdd BLAST58
Compositional biasi715 – 722Poly-Pro8

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM171 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTDH, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183184

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_019729_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8MVW0

Identification of Orthologs from Complete Genome Data

More...
OMAi
RPLMVFH

Database of Orthologous Groups

More...
OrthoDBi
615320at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8MVW0

TreeFam database of animal gene trees

More...
TreeFami
TF331338

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018890, Uncharacterised_FAM171

The PANTHER Classification System

More...
PANTHERi
PTHR31626, PTHR31626, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10577, UPF0560, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A8MVW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPASGPSVL ARLLPLLGLL LGSASRAPGK SPPEPPSPQE ILIKVQVYVS
60 70 80 90 100
GELVPLARAS VDVFGNRTLL AAGTTDSEGV ATLPLSYRLG TWVLVTAARP
110 120 130 140 150
GFLTNSVPWR VDKLPLYASV SLYLLPERPA TLILYEDLVH ILLGSPGARS
160 170 180 190 200
QPLVQFQRRA ARLPVSSTYS QLWASLTPAS TQQEMRAFPA FLGTEASSSG
210 220 230 240 250
NGSWLELMPL TAVSVHLLTG NGTEVPLSGP IHLSLPVPSE TRALTVGTSI
260 270 280 290 300
PAWRFDPKSG LWVRNGTGVI RKEGRQLYWT FVSPQLGYWV AAMASPTAGL
310 320 330 340 350
VTITSGIQDI GTYHTIFLLT ILAALALLVL ILLCLLIYYC RRRCLKPRQQ
360 370 380 390 400
HRKLQLSGPS DGNKRDQATS MSQLHLICGG PLEPAPSGDP EAPPPGPLHS
410 420 430 440 450
AFSSSRDLAS SRDDFFRTKP RSASRPAAEP SGARGGESAG LKGARSAEGP
460 470 480 490 500
GGLEPGLEEH RRGPSGAAAF LHEPPSPPPP FDHYLGHKGA AEGKTPDFLL
510 520 530 540 550
SQSVDQLARP PSLGQAGQLI FCGSIDHLKD NVYRNVMPTL VIPAHYVRLG
560 570 580 590 600
GEAGAAGVGD EPAPPEGTAP GPARAFPQPD PQRPQMPGHS GPGGEGGGGG
610 620 630 640 650
GEGWGAGRAA PVSGSVTIPV LFNESTMAQL NGELQALTEK KLLELGVKPH
660 670 680 690 700
PRAWFVSLDG RSNSQVRHSY IDLQAGGGAR STDASLDSGV DVHEARPARR
710 720 730 740 750
RPAREERERA PPAAPPPPPA PPRLALSEDT EPSSSESRTG LCSPEDNSLT
760 770 780 790 800
PLLDEVAAPE GRAATVPRGR GRSRGDSSRS SASELRRDSL TSPEDELGAE
810 820
VGDEAGDKKS PWQRREERPL MVFNVK
Length:826
Mass (Da):87,435
Last modified:December 4, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2845FC542702C3E0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EMG4K7EMG4_HUMAN
Protein FAM171A2
FAM171A2
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC003043 Genomic DNA No translation available.
CH471178 Genomic DNA Translation: EAW51598.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45701.1

NCBI Reference Sequences

More...
RefSeqi
NP_940877.2, NM_198475.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000293443; ENSP00000293443; ENSG00000161682

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284069

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284069

UCSC genome browser

More...
UCSCi
uc002igs.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003043 Genomic DNA No translation available.
CH471178 Genomic DNA Translation: EAW51598.1
CCDSiCCDS45701.1
RefSeqiNP_940877.2, NM_198475.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi129748, 36 interactors
IntActiA8MVW0, 18 interactors
STRINGi9606.ENSP00000293443

PTM databases

GlyConnecti1658, 3 N-Linked glycans (2 sites)
GlyGeniA8MVW0, 4 sites
iPTMnetiA8MVW0
PhosphoSitePlusiA8MVW0
SwissPalmiA8MVW0

Polymorphism and mutation databases

BioMutaiFAM171A2

Proteomic databases

EPDiA8MVW0
jPOSTiA8MVW0
MassIVEiA8MVW0
MaxQBiA8MVW0
PaxDbiA8MVW0
PeptideAtlasiA8MVW0
PRIDEiA8MVW0
ProteomicsDBi2208

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
8250, 26 antibodies

Genome annotation databases

EnsembliENST00000293443; ENSP00000293443; ENSG00000161682
GeneIDi284069
KEGGihsa:284069
UCSCiuc002igs.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
284069
DisGeNETi284069
EuPathDBiHostDB:ENSG00000161682.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM171A2
HGNCiHGNC:30480, FAM171A2
HPAiENSG00000161682, Tissue enhanced (brain)
neXtProtiNX_A8MVW0
OpenTargetsiENSG00000161682
PharmGKBiPA162387197

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QTDH, Eukaryota
GeneTreeiENSGT00950000183184
HOGENOMiCLU_019729_0_0_1
InParanoidiA8MVW0
OMAiRPLMVFH
OrthoDBi615320at2759
PhylomeDBiA8MVW0
TreeFamiTF331338

Enzyme and pathway databases

PathwayCommonsiA8MVW0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
284069, 4 hits in 879 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM171A2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
284069
PharosiA8MVW0, Tdark

Protein Ontology

More...
PROi
PR:A8MVW0
RNActiA8MVW0, protein

Gene expression databases

BgeeiENSG00000161682, Expressed in cortical plate and 125 other tissues
ExpressionAtlasiA8MVW0, baseline and differential
GenevisibleiA8MVW0, HS

Family and domain databases

InterProiView protein in InterPro
IPR018890, Uncharacterised_FAM171
PANTHERiPTHR31626, PTHR31626, 1 hit
PfamiView protein in Pfam
PF10577, UPF0560, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1712_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MVW0
Secondary accession number(s): A8MQB4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: December 4, 2007
Last modified: August 12, 2020
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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