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Protein
Submitted name:

C-type lectin domain family 12 member A

Gene

CLEC12A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
C-type lectin domain family 12 member AImported
Gene namesi
Name:CLEC12AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000172322.13
HGNCiHGNC:31713 CLEC12A

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 68HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172322

PTM / Processingi

Proteomic databases

MaxQBiA8MVL9
PeptideAtlasiA8MVL9
PRIDEiA8MVL9

Expressioni

Gene expression databases

BgeeiENSG00000172322 Expressed in 105 organ(s), highest expression level in leukocyte
ExpressionAtlasiA8MVL9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA8MVL9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili68 – 88Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00700000104266
HOGENOMiHOG000111777

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
SUPFAMiSSF56436 SSF56436, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A8MVL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEEVTYADL QFQNSSEMEK IPEIGKFGEK APPAPSHVWR PAALFLTLLC
60 70 80 90 100
LLLLIGLGVL ASMFHVTLKI EMKKMNKLQN ISEELQRNIS LQLMSNMNIS
110 120 130 140 150
NKIRNLSTTL QTIATKLCRE LYSKEQEHKC KPCPRRWIWH KDSCYFLSDD
160
VQTWQESKMA CAAQN
Length:165
Mass (Da):19,034
Last modified:June 28, 2011 - v2
Checksum:i42A02693F8B71467
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5QGZ9CL12A_HUMAN
C-type lectin domain family 12 memb...
CLEC12A CLL1, DCAL2, MICL
265Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei165Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091814 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000396507; ENSP00000379764; ENSG00000172322
UCSCiuc058lbf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091814 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA8MVL9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiA8MVL9
PeptideAtlasiA8MVL9
PRIDEiA8MVL9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000396507; ENSP00000379764; ENSG00000172322
UCSCiuc058lbf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000172322.13
HGNCiHGNC:31713 CLEC12A
OpenTargetsiENSG00000172322
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00700000104266
HOGENOMiHOG000111777

Gene expression databases

BgeeiENSG00000172322 Expressed in 105 organ(s), highest expression level in leukocyte
ExpressionAtlasiA8MVL9 baseline and differential

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
SUPFAMiSSF56436 SSF56436, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA8MVL9_HUMAN
AccessioniPrimary (citable) accession number: A8MVL9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 75 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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