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Entry version 74 (13 Feb 2019)
Sequence version 2 (14 Oct 2008)
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Protein

Protein CEBPZOS

Gene

CEBPZOS

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein CEBPZOSCurated
Alternative name(s):
CEBPZ antisense RNA 1Imported
CEBPZ opposite strandImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CEBPZOSImported
Synonyms:CEBPZ-AS1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000218739.9

Human Gene Nomenclature Database

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HGNCi
HGNC:49288 CEBPZOS

neXtProt; the human protein knowledge platform

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neXtProti
NX_A8MTT3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei15 – 32HelicalSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000218739

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CEBPZOS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004323721 – 80Protein CEBPZOSAdd BLAST80

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
A8MTT3

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
A8MTT3

MaxQB - The MaxQuant DataBase

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MaxQBi
A8MTT3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8MTT3

PRoteomics IDEntifications database

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PRIDEi
A8MTT3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
A8MTT3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8MTT3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000218739 Expressed in 192 organ(s), highest expression level in left adrenal gland

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
A8MTT3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053866

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
A8MTT3, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
A8MTT3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
A8MTT3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410J0MX Eukaryota
ENOG410Y42A LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00500000045333

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000015274

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG093727

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8MTT3

Identification of Orthologs from Complete Genome Data

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OMAi
FLFKKMN

Database of Orthologous Groups

More...
OrthoDBi
1552801at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8MTT3

TreeFam database of animal gene trees

More...
TreeFami
TF353548

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR037764 CEBPZOS

The PANTHER Classification System

More...
PANTHERi
PTHR38001 PTHR38001, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A8MTT3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARTLEPLAK KIFKGVLVAE LVGVFGAYFL FSKMHTSQDF RQTMSKKYPF
60 70 80
ILEVYYKSTE KSGMYGIREL DQKTWLNSKN
Length:80
Mass (Da):9,336
Last modified:October 14, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8BBD64C8DBD5BBCB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007390 Genomic DNA No translation available.
CH471053 Genomic DNA Translation: EAX00404.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS82435.1

NCBI Reference Sequences

More...
RefSeqi
NP_001309302.1, NM_001322373.1
NP_001309303.1, NM_001322374.1
NP_001309304.1, NM_001322375.1
NP_001309305.1, NM_001322376.1
XP_016858595.1, XM_017003106.1
XP_016858596.1, XM_017003107.1
XP_016858597.1, XM_017003108.1
XP_016858598.1, XM_017003109.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.666958
Hs.743972

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000392061; ENSP00000383895; ENSG00000218739
ENST00000397064; ENSP00000380254; ENSG00000218739
ENST00000397226; ENSP00000380403; ENSG00000218739
ENST00000402297; ENSP00000384331; ENSG00000218739
ENST00000406711; ENSP00000384813; ENSG00000218739

Database of genes from NCBI RefSeq genomes

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GeneIDi
100505876

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:100505876

UCSC genome browser

More...
UCSCi
uc002rpx.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007390 Genomic DNA No translation available.
CH471053 Genomic DNA Translation: EAX00404.1
CCDSiCCDS82435.1
RefSeqiNP_001309302.1, NM_001322373.1
NP_001309303.1, NM_001322374.1
NP_001309304.1, NM_001322375.1
NP_001309305.1, NM_001322376.1
XP_016858595.1, XM_017003106.1
XP_016858596.1, XM_017003107.1
XP_016858597.1, XM_017003108.1
XP_016858598.1, XM_017003109.1
UniGeneiHs.666958
Hs.743972

3D structure databases

ProteinModelPortaliA8MTT3
SMRiA8MTT3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA8MTT3, 1 interactor

PTM databases

iPTMnetiA8MTT3
PhosphoSitePlusiA8MTT3

Polymorphism and mutation databases

BioMutaiCEBPZOS

Proteomic databases

EPDiA8MTT3
jPOSTiA8MTT3
MaxQBiA8MTT3
PaxDbiA8MTT3
PRIDEiA8MTT3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000392061; ENSP00000383895; ENSG00000218739
ENST00000397064; ENSP00000380254; ENSG00000218739
ENST00000397226; ENSP00000380403; ENSG00000218739
ENST00000402297; ENSP00000384331; ENSG00000218739
ENST00000406711; ENSP00000384813; ENSG00000218739
GeneIDi100505876
KEGGihsa:100505876
UCSCiuc002rpx.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100505876
EuPathDBiHostDB:ENSG00000218739.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CEBPZOS
HGNCiHGNC:49288 CEBPZOS
HPAiHPA053866
neXtProtiNX_A8MTT3
OpenTargetsiENSG00000218739

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J0MX Eukaryota
ENOG410Y42A LUCA
GeneTreeiENSGT00500000045333
HOGENOMiHOG000015274
HOVERGENiHBG093727
InParanoidiA8MTT3
OMAiFLFKKMN
OrthoDBi1552801at2759
PhylomeDBiA8MTT3
TreeFamiTF353548

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CEBPZOS human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
100505876

Protein Ontology

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PROi
PR:A8MTT3

Gene expression databases

BgeeiENSG00000218739 Expressed in 192 organ(s), highest expression level in left adrenal gland
GenevisibleiA8MTT3 HS

Family and domain databases

InterProiView protein in InterPro
IPR037764 CEBPZOS
PANTHERiPTHR38001 PTHR38001, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCEBOS_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MTT3
Secondary accession number(s): A8MUR5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 4, 2015
Last sequence update: October 14, 2008
Last modified: February 13, 2019
This is version 74 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
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