Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Killer cell immunoglobulin-like receptor 2DL4

Gene

KIR2DL4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Killer cell immunoglobulin-like receptor 2DL4Imported
Gene namesi
Name:KIR2DL4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000189013.14
HGNCiHGNC:6332 KIR2DL4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei243 – 261HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000189013

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501508666523 – 398Sequence analysisAdd BLAST376

Proteomic databases

PRIDEiA8MT18

Expressioni

Gene expression databases

BgeeiENSG00000189013 Expressed in 51 organ(s), highest expression level in blood
ExpressionAtlasiA8MT18 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA8MT18
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 119IGInterPro annotationAdd BLAST85
Domaini130 – 217IGInterPro annotationAdd BLAST88

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119033
HOGENOMiHOG000234396
HOVERGENiHBG074353

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013151 Immunoglobulin
PfamiView protein in Pfam
PF00047 ig, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 30 potential isoforms that are computationally mapped.Show allAlign All

A8MT18-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XMSPTVIILA CLGFFLDQSV WAHVGGQDKP FCSAWPSAVV PQGGHVTLRC
60 70 80 90 100
HYRRGFNIFT LYKKDGVPVP ELYNRIFWNS FLISPVTPAH AGTYRCRGFH
110 120 130 140 150
PHSPTEWSAP SNPLVIMVTG LYEKPSLTAR PGPTVRAGEN VTLSCSSQSS
160 170 180 190 200
FDIYHLSREG EAHELRLPAV PSINGTFQAD FPLGPATHGE TYRCFGSFHG
210 220 230 240 250
SPYEWSDPSD PLPVSVTGNP SSSWPSPTEP SFKTGIARHL HAVIRYSVAI
260 270 280 290 300
ILFTILPFFL LHRWCSKKKV SLTKQRPENS GPCAEAGWEH ADAAVMNQEP
310 320 330 340 350
AGHRTVNRED SDEQDPQEVT YAQLDHCIFT QRKITGPSQR SKRPSTDTSV
360 370 380 390
CIELPNAEPR ALSPAHEHHS QALMGSSRET TALSQTQLAS SNVPAAGI
Length:398
Mass (Da):43,729
Last modified:February 19, 2014 - v3
Checksum:i8E9DAC408B3EBCE4
GO

Computationally mapped potential isoform sequencesi

There are 30 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99706KI2L4_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4 CD158D, KIR103AS
377Annotation score:
Q86U48Q86U48_HUMAN
KIR2DL4
KIR2DL4 KIR-2DL4
377Annotation score:
A0A0B4J1S6A0A0B4J1S6_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
273Annotation score:
K7RE46K7RE46_HUMAN
KIR2DL4
KIR2DL4
273Annotation score:
K7QUT1K7QUT1_HUMAN
KIR2DL4
KIR2DL4
377Annotation score:
A0A0C4ZNX8A0A0C4ZNX8_HUMAN
KIR2DL4 Killer-cell Immunoglobulin-...
KIR2DL4
377Annotation score:
A0A0G2JP28A0A0G2JP28_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
273Annotation score:
A0A0G2JLM0A0A0G2JLM0_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
312Annotation score:
A0A0G2JMF5A0A0G2JMF5_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
312Annotation score:
A0A0G2JNG7A0A0G2JNG7_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
310Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245128 Genomic DNA No translation available.
KP420439 Genomic DNA No translation available.
KP420444 Genomic DNA No translation available.
KU842452 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000396289; ENSP00000379584; ENSG00000189013
ENST00000638428; ENSP00000492061; ENSG00000284013
ENST00000639569; ENSP00000491554; ENSG00000284365
ENST00000641000; ENSP00000492041; ENSG00000283961
UCSCiuc061ctj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245128 Genomic DNA No translation available.
KP420439 Genomic DNA No translation available.
KP420444 Genomic DNA No translation available.
KU842452 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA8MT18
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA8MT18

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000396289; ENSP00000379584; ENSG00000189013
ENST00000638428; ENSP00000492061; ENSG00000284013
ENST00000639569; ENSP00000491554; ENSG00000284365
ENST00000641000; ENSP00000492041; ENSG00000283961
UCSCiuc061ctj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000189013.14
HGNCiHGNC:6332 KIR2DL4
OpenTargetsiENSG00000189013
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119033
HOGENOMiHOG000234396
HOVERGENiHBG074353

Gene expression databases

BgeeiENSG00000189013 Expressed in 51 organ(s), highest expression level in blood
ExpressionAtlasiA8MT18 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013151 Immunoglobulin
PfamiView protein in Pfam
PF00047 ig, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA8MT18_HUMAN
AccessioniPrimary (citable) accession number: A8MT18
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: February 19, 2014
Last modified: October 10, 2018
This is version 72 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again