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UniProtKB - A8MQ03 (CRTP1_HUMAN)
Protein
Cysteine-rich tail protein 1
Gene
CYSRT1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: IntAct
Enzyme and pathway databases
PathwayCommonsi | A8MQ03 |
SignaLinki | A8MQ03 |
Names & Taxonomyi
Protein namesi | Recommended name: Cysteine-rich tail protein 1 |
Gene namesi | Name:CYSRT1 Synonyms:C9orf169 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30529, CYSRT1 |
neXtProti | NX_A8MQ03 |
VEuPathDBi | HostDB:ENSG00000197191 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000197191 |
PharmGKBi | PA162380848 |
Miscellaneous databases
Pharosi | A8MQ03, Tdark |
Genetic variation databases
BioMutai | CYSRT1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000332287 | 1 – 144 | Cysteine-rich tail protein 1Add BLAST | 144 |
Proteomic databases
EPDi | A8MQ03 |
jPOSTi | A8MQ03 |
MassIVEi | A8MQ03 |
MaxQBi | A8MQ03 |
PaxDbi | A8MQ03 |
PeptideAtlasi | A8MQ03 |
PRIDEi | A8MQ03 |
ProteomicsDBi | 1929 |
PTM databases
iPTMneti | A8MQ03 |
PhosphoSitePlusi | A8MQ03 |
SwissPalmi | A8MQ03 |
Expressioni
Gene expression databases
ExpressionAtlasi | A8MQ03, baseline and differential |
Organism-specific databases
HPAi | ENSG00000197191, Tissue enriched (esophagus) |
Interactioni
Binary interactionsi
A8MQ03
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 132001, 503 interactors |
IntActi | A8MQ03, 502 interactors |
STRINGi | 9606.ENSP00000386453 |
Miscellaneous databases
RNActi | A8MQ03, protein |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 51 – 105 | DisorderedSequence analysisAdd BLAST | 55 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 74 – 100 | Polar residuesSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Belongs to the CYSRT1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502SD8F, Eukaryota |
GeneTreei | ENSGT00390000003233 |
InParanoidi | A8MQ03 |
OrthoDBi | 1474726at2759 |
PhylomeDBi | A8MQ03 |
TreeFami | TF338434 |
Family and domain databases
InterProi | View protein in InterPro IPR018904, UPF0574 |
PANTHERi | PTHR37879, PTHR37879, 1 hit |
Pfami | View protein in Pfam PF10631, DUF2477, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A8MQ03-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDPQEMVVKN PYAHISIPRA HLRPDLGQQL EVASTCSSSS EMQPLPVGPC
60 70 80 90 100
APEPTHLLQP TEVPGPKGAK GNQGAAPIQN QQAWQQPGNP YSSSQRQAGL
110 120 130 140
TYAGPPPAGR GDDIAHHCCC CPCCHCCHCP PFCRCHSCCC CVIS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketB8A4K4 | B8A4K4_HUMAN | Cysteine-rich tail protein 1 | CYSRT1 | 184 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 108 | A → V in AAH52297 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX255925 Genomic DNA No translation available. BC052297 mRNA Translation: AAH52297.1 |
CCDSi | CCDS48064.2 |
RefSeqi | NP_945352.3, NM_199001.3 |
Genome annotation databases
Ensembli | ENST00000650725; ENSP00000498316; ENSG00000197191 |
GeneIDi | 375791 |
KEGGi | hsa:375791 |
MANE-Selecti | ENST00000650725.2; ENSP00000498316.1; NM_199001.5; NP_945352.4 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX255925 Genomic DNA No translation available. BC052297 mRNA Translation: AAH52297.1 |
CCDSi | CCDS48064.2 |
RefSeqi | NP_945352.3, NM_199001.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 132001, 503 interactors |
IntActi | A8MQ03, 502 interactors |
STRINGi | 9606.ENSP00000386453 |
PTM databases
iPTMneti | A8MQ03 |
PhosphoSitePlusi | A8MQ03 |
SwissPalmi | A8MQ03 |
Genetic variation databases
BioMutai | CYSRT1 |
Proteomic databases
EPDi | A8MQ03 |
jPOSTi | A8MQ03 |
MassIVEi | A8MQ03 |
MaxQBi | A8MQ03 |
PaxDbi | A8MQ03 |
PeptideAtlasi | A8MQ03 |
PRIDEi | A8MQ03 |
ProteomicsDBi | 1929 |
Protocols and materials databases
Antibodypediai | 8700, 53 antibodies from 9 providers |
DNASUi | 375791 |
Genome annotation databases
Ensembli | ENST00000650725; ENSP00000498316; ENSG00000197191 |
GeneIDi | 375791 |
KEGGi | hsa:375791 |
MANE-Selecti | ENST00000650725.2; ENSP00000498316.1; NM_199001.5; NP_945352.4 |
Organism-specific databases
CTDi | 375791 |
GeneCardsi | CYSRT1 |
HGNCi | HGNC:30529, CYSRT1 |
HPAi | ENSG00000197191, Tissue enriched (esophagus) |
neXtProti | NX_A8MQ03 |
OpenTargetsi | ENSG00000197191 |
PharmGKBi | PA162380848 |
VEuPathDBi | HostDB:ENSG00000197191 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502SD8F, Eukaryota |
GeneTreei | ENSGT00390000003233 |
InParanoidi | A8MQ03 |
OrthoDBi | 1474726at2759 |
PhylomeDBi | A8MQ03 |
TreeFami | TF338434 |
Enzyme and pathway databases
PathwayCommonsi | A8MQ03 |
SignaLinki | A8MQ03 |
Miscellaneous databases
BioGRID-ORCSi | 375791, 4 hits in 651 CRISPR screens |
ChiTaRSi | CYSRT1, human |
GenomeRNAii | 375791 |
Pharosi | A8MQ03, Tdark |
PROi | PR:A8MQ03 |
RNActi | A8MQ03, protein |
Gene expression databases
ExpressionAtlasi | A8MQ03, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR018904, UPF0574 |
PANTHERi | PTHR37879, PTHR37879, 1 hit |
Pfami | View protein in Pfam PF10631, DUF2477, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CRTP1_HUMAN | |
Accessioni | A8MQ03Primary (citable) accession number: A8MQ03 Secondary accession number(s): Q86UY7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 29, 2008 |
Last sequence update: | December 4, 2007 | |
Last modified: | February 23, 2022 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families