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Entry version 85 (22 Apr 2020)
Sequence version 1 (04 Dec 2007)
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Protein

Cysteine-rich tail protein 1

Gene

CYSRT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cysteine-rich tail protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CYSRT1
Synonyms:C9orf169
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30529 CYSRT1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A8MQ03

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000197191

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380848

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

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Pharosi
A8MQ03 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CYSRT1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003322871 – 144Cysteine-rich tail protein 1Add BLAST144

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
A8MQ03

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
A8MQ03

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
A8MQ03

MaxQB - The MaxQuant DataBase

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MaxQBi
A8MQ03

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8MQ03

PRoteomics IDEntifications database

More...
PRIDEi
A8MQ03

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
1929

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
A8MQ03

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8MQ03

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
A8MQ03

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A8MQ03 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

A8MQ03
With#Exp.IntAct
itself3EBI-3867333,EBI-3867333
Q96EJ43EBI-3867333,EBI-750454
A1CF [Q9NQ94]3EBI-3867333,EBI-2809489
ACY3 [Q96HD9]3EBI-3867333,EBI-3916242
ADAM12 - isoform 4 [O43184-4]6EBI-3867333,EBI-12006944
ADAMTSL3 [P82987]3EBI-3867333,EBI-10221726
ADAMTSL4 - isoform 3 [Q6UY14-3]3EBI-3867333,EBI-10173507
ADAMTSL5 [Q6ZMM2]3EBI-3867333,EBI-9075891
AGXT [P21549]3EBI-3867333,EBI-727098
ALDH3B1 [P43353]3EBI-3867333,EBI-2558314
ALPP [P05187]3EBI-3867333,EBI-1211484
AMMECR1 - isoform 3 [Q9Y4X0-3]3EBI-3867333,EBI-12823597
ANAPC11 - isoform 2 [Q9NYG5-2]3EBI-3867333,EBI-12224467
ANKS1A [Q49AR9]3EBI-3867333,EBI-11954519
AQP1 [P29972]3EBI-3867333,EBI-745213
AREG [P15514]3EBI-3867333,EBI-953674
ARHGAP9 [Q9BRR9]3EBI-3867333,EBI-750254
ARID5A [Q03989]3EBI-3867333,EBI-948603
ASTL [Q6HA08]3EBI-3867333,EBI-11998350
ATG9A - isoform 3 [Q7Z3C6-3]3EBI-3867333,EBI-12006308
ATPAF2 [Q8N5M1]3EBI-3867333,EBI-1166928
AUTS2 - isoform 2 [Q8WXX7-2]3EBI-3867333,EBI-12140769
AVPI1 [Q5T686]3EBI-3867333,EBI-8640233
B4GALT7 [Q9UBV7]3EBI-3867333,EBI-10319970
BAG3 [O95817]3EBI-3867333,EBI-747185
BAG6 - isoform 2 [P46379-2]3EBI-3867333,EBI-10988864
BAHD1 [Q8TBE0]3EBI-3867333,EBI-742750
BAIAP2L1 [Q9UHR4]3EBI-3867333,EBI-2483278
BEX1 [Q9HBH7]3EBI-3867333,EBI-7162175
BEX2 [Q9BXY8]3EBI-3867333,EBI-745073
BLCAP [P62952]3EBI-3867333,EBI-3895726
BMP7 [P18075]3EBI-3867333,EBI-1035195
BSCL2 [J3KQ12]3EBI-3867333,EBI-11532900
C11orf87 [Q6NUJ2]3EBI-3867333,EBI-6660291
C19orf54 - isoform 3 [Q5BKX5-3]3EBI-3867333,EBI-11976299
C19orf57 - isoform 2 [Q0VDD7-2]3EBI-3867333,EBI-12040255
C22orf39 [Q6P5X5]6EBI-3867333,EBI-7317823
C4orf45 [Q96LM5]3EBI-3867333,EBI-12020542
C7orf31 [Q8N865]3EBI-3867333,EBI-10174456
CACNA1S [Q13698]3EBI-3867333,EBI-5329490
CARD10 [Q9BWT7]3EBI-3867333,EBI-3866279
CARD9 - isoform 2 [Q9H257-2]3EBI-3867333,EBI-11530605
CARHSP1 [Q9Y2V2]3EBI-3867333,EBI-718719
CATIP [Q7Z7H3]3EBI-3867333,EBI-10258233
CATSPER1 [Q8NEC5]3EBI-3867333,EBI-744545
CBLL2 [Q8N7E2]3EBI-3867333,EBI-12196065
CBX2 - isoform 2 [Q14781-2]3EBI-3867333,EBI-11974585
CCDC120 [Q96HB5]3EBI-3867333,EBI-744556
CCER1 [Q8TC90]3EBI-3867333,EBI-746041
CCNK - isoform 2 [O75909-2]3EBI-3867333,EBI-12010594
CD300LG [Q6UXG3]3EBI-3867333,EBI-10254587
CDKL3 [Q8IVW4]3EBI-3867333,EBI-3919850
CELF5 [Q8N6W0]3EBI-3867333,EBI-12139335
CERCAM [Q5T4B2]3EBI-3867333,EBI-12261896
CERK [Q8TCT0]3EBI-3867333,EBI-10274247
CES1 - isoform 3 [P23141-3]3EBI-3867333,EBI-12360993
CFAP206 [Q8IYR0]3EBI-3867333,EBI-749051
CFP [P27918]3EBI-3867333,EBI-9038570
CHCHD2 [Q9Y6H1]3EBI-3867333,EBI-2321769
CHCHD3 [Q9NX63]6EBI-3867333,EBI-743375
CHIC2 [Q9UKJ5]3EBI-3867333,EBI-741528
CHRD [Q9H2X0]3EBI-3867333,EBI-947551
CHRNG - isoform 2 [P07510-2]3EBI-3867333,EBI-11979451
CLCNKA - isoform 3 [P51800-3]3EBI-3867333,EBI-11980535
CLDN19 - isoform 2 [Q8N6F1-2]3EBI-3867333,EBI-12256978
CLDN2 [P57739]3EBI-3867333,EBI-751440
CLEC18A [A5D8T8]3EBI-3867333,EBI-10173491
CNNM3 [Q8NE01]3EBI-3867333,EBI-741032
CNTF [P26441]3EBI-3867333,EBI-1050897
COA5 [Q86WW8]3EBI-3867333,EBI-5458774
COL8A1 [P27658]6EBI-3867333,EBI-747133
COMP [P49747]3EBI-3867333,EBI-2531022
CPT2 [P23786]3EBI-3867333,EBI-6269566
CRCT1 [Q9UGL9]3EBI-3867333,EBI-713677
CREB5 - isoform 3 [Q02930-3]3EBI-3867333,EBI-10192698
CRH [P06850]3EBI-3867333,EBI-3870390
CRY2 [Q49AN0]3EBI-3867333,EBI-2212355
CRYBA1 [P05813]3EBI-3867333,EBI-7043337
CRYBA2 [P53672]3EBI-3867333,EBI-750444
CSF1 [P09603]3EBI-3867333,EBI-2872294
CST2 [P09228]3EBI-3867333,EBI-8832659
CST9L [Q9H4G1]3EBI-3867333,EBI-3923092
CTRC [Q99895]3EBI-3867333,EBI-10295404
CTSG [P08311]3EBI-3867333,EBI-5462635
CTSZ [Q9UBR2]3EBI-3867333,EBI-8636823
CUTA - isoform C [O60888-3]3EBI-3867333,EBI-10979071
CYP21A2 [Q08AG9]3EBI-3867333,EBI-14156412
DACT2 - isoform 3 [Q5SW24-3]3EBI-3867333,EBI-11994826
DALRD3 - isoform 2 [Q5D0E6-2]3EBI-3867333,EBI-9090939
DBF4B - isoform 2 [Q8NFT6-2]3EBI-3867333,EBI-12205861
DCDC2B [A2VCK2]3EBI-3867333,EBI-10173222
DDX43 [Q9NXZ2]3EBI-3867333,EBI-10316543
DLGAP2 - isoform 3 [Q9P1A6-3]3EBI-3867333,EBI-12019838
DMAC2 - isoform 2 [Q9NW81-2]3EBI-3867333,EBI-22730614
DMRT3 [Q9NQL9]3EBI-3867333,EBI-9679045
DNAJA3 [Q96EY1]3EBI-3867333,EBI-356767
DNASE1L3 [Q13609]3EBI-3867333,EBI-9512718
DOCK2 [Q92608]3EBI-3867333,EBI-448771
DVL3 [Q92997]3EBI-3867333,EBI-739789
ECE1 [P42892]3EBI-3867333,EBI-2859983
ECM1 [Q16610]3EBI-3867333,EBI-947964
EFEMP1 [Q12805]5EBI-3867333,EBI-536772
EFEMP2 [O95967]3EBI-3867333,EBI-743414
EMC7 [Q9NPA0]3EBI-3867333,EBI-6309137
ENKD1 [Q9H0I2]3EBI-3867333,EBI-744099
EPS8L1 - isoform 2 [Q8TE68-2]3EBI-3867333,EBI-12003490
ERH [P84090]3EBI-3867333,EBI-711389
ESR2 - isoform 3 [Q92731-3]3EBI-3867333,EBI-12259414
ETNK2 [Q9NVF9]3EBI-3867333,EBI-751864
EVA1B [Q9NVM1]3EBI-3867333,EBI-10314666
FADS6 [Q8N9I5]3EBI-3867333,EBI-3943864
FAM102A - isoform 3 [Q5T9C2-3]3EBI-3867333,EBI-11980989
FAM124B - isoform 2 [Q9H5Z6-2]3EBI-3867333,EBI-11986315
FAM214B [Q7L5A3]3EBI-3867333,EBI-745689
FAM221A [A4D161]3EBI-3867333,EBI-11960181
FAM221B [A6H8Z2]3EBI-3867333,EBI-12006844
FAM222B [Q8WU58]3EBI-3867333,EBI-2807642
FAM71C [Q8NEG0]3EBI-3867333,EBI-752049
FAM83A [Q86UY5]3EBI-3867333,EBI-1384254
FAM90A1 [Q86YD7]3EBI-3867333,EBI-6658203
FANCL [Q9NW38]3EBI-3867333,EBI-2339898
FARS2 [O95363]3EBI-3867333,EBI-2513774
FASLG [P48023]3EBI-3867333,EBI-495538
FBXW5 [Q969U6]3EBI-3867333,EBI-741068
FEZF1 [A0PJY2]3EBI-3867333,EBI-11988727
FHL3 [Q13643]3EBI-3867333,EBI-741101
FLNA - isoform 2 [P21333-2]3EBI-3867333,EBI-9641086
FOXD2 [O60548]3EBI-3867333,EBI-17282008
FOXD4L1 [Q9NU39]3EBI-3867333,EBI-11320806
FOXD4L3 [Q6VB84]3EBI-3867333,EBI-11961494
FOXH1 [O75593]3EBI-3867333,EBI-1759806
FRS3 [O43559]3EBI-3867333,EBI-725515
FRZB [Q92765]3EBI-3867333,EBI-2822789
FZD10 [Q9ULW2]3EBI-3867333,EBI-8803802
GAS8 [O95995]3EBI-3867333,EBI-1052570
GATA2 [P23769]3EBI-3867333,EBI-2806671
GATA3 - isoform 2 [P23771-2]3EBI-3867333,EBI-6672518
GATA5 [Q9BWX5]3EBI-3867333,EBI-12132270
GCSAM [Q8N6F7]3EBI-3867333,EBI-10267082
GEM [P55040]3EBI-3867333,EBI-744104
GGN [Q86UU5]3EBI-3867333,EBI-10259069
GLB1L2 [Q8IW92]3EBI-3867333,EBI-11954377
GLP1R [P43220]3EBI-3867333,EBI-7466542
GNE - isoform 2 [Q9Y223-2]3EBI-3867333,EBI-11975289
GNG13 [Q9P2W3]3EBI-3867333,EBI-11427343
GPANK1 [O95872]3EBI-3867333,EBI-751540
GPATCH2L - isoform 2 [Q9NWQ4-1]3EBI-3867333,EBI-11959863
GPS2 [Q13227]3EBI-3867333,EBI-713355
GRN [P28799]3EBI-3867333,EBI-747754
GSTP1 [P09211]3EBI-3867333,EBI-353467
GUCD1 - isoform 2 [Q96NT3-2]3EBI-3867333,EBI-11978177
H2AFY [O75367]3EBI-3867333,EBI-2868511
HBZ [P02008]3EBI-3867333,EBI-719843
hCG_2003792 [A0A024R5S0]3EBI-3867333,EBI-10188461
HCK - isoform 2 [P08631-2]3EBI-3867333,EBI-9834454
HDHD3 [Q9BSH5]3EBI-3867333,EBI-745201
HEY2 [Q9UBP5]3EBI-3867333,EBI-750630
HHEX [Q03014]3EBI-3867333,EBI-747421
HLX [Q14774]3EBI-3867333,EBI-6678255
HOXA1 [P49639]6EBI-3867333,EBI-740785
HOXB5 [P09067]3EBI-3867333,EBI-3893317
HOXB9 [P17482]3EBI-3867333,EBI-745290
HOXC8 [P31273]3EBI-3867333,EBI-1752118
HOXC9 [P31274]3EBI-3867333,EBI-1779423
HR [O43593]3EBI-3867333,EBI-2880706
HRG [P04196]3EBI-3867333,EBI-3915012
HSBP1 [O75506]3EBI-3867333,EBI-748664
HSD3B7 [Q9H2F3]3EBI-3867333,EBI-3918847
HSPA12B [Q96MM6]3EBI-3867333,EBI-10291310
HSPD1 [P10809]3EBI-3867333,EBI-352528
HYAL2 [Q12891]3EBI-3867333,EBI-2806068
ICAM1 [P05362]3EBI-3867333,EBI-1035358
ICAM4 - isoform 3 [Q14773-3]3EBI-3867333,EBI-10233928
IL16 - isoform 2 [Q14005-2]3EBI-3867333,EBI-17178971
INCA1 [Q0VD86]3EBI-3867333,EBI-6509505
INO80B [Q9C086]3EBI-3867333,EBI-715611
INPP5D - isoform 2 [Q92835-2]3EBI-3867333,EBI-9092209
INS [P01308]3EBI-3867333,EBI-7090529
IQUB [Q8NA54]3EBI-3867333,EBI-10220600
ISYNA1 [Q9NPH2]3EBI-3867333,EBI-720563
ITGB2 [P05107]3EBI-3867333,EBI-300173
ITGB4 - isoform Beta-4A [P16144-2]3EBI-3867333,EBI-11051601
ITGB5 [P18084]3EBI-3867333,EBI-1223434
JOSD1 [Q15040]3EBI-3867333,EBI-2510602
KCNS2 [Q9ULS6]3EBI-3867333,EBI-10323864
KCTD15 - isoform 2 [Q96SI1-2]3EBI-3867333,EBI-12382297
KIAA1683 [A0JP07]3EBI-3867333,EBI-10171456
KLHL38 [Q2WGJ6]3EBI-3867333,EBI-6426443
KLK8 [O60259]3EBI-3867333,EBI-3915857
KPRP [Q5T749]7EBI-3867333,EBI-10981970
KRT20 [P35900]3EBI-3867333,EBI-742094
KRT31 [Q15323]3EBI-3867333,EBI-948001
KRT33B [Q14525]3EBI-3867333,EBI-1049638
KRT34 [O76011]5EBI-3867333,EBI-1047093
KRT81 [Q14533]3EBI-3867333,EBI-739648
KRT83 [P78385]3EBI-3867333,EBI-10221390
KRT85 [P78386]3EBI-3867333,EBI-1049371
KRT86 [O43790]3EBI-3867333,EBI-9996498
KRTAP1-1 [Q07627]3EBI-3867333,EBI-11959885
KRTAP1-5 [Q9BYS1]3EBI-3867333,EBI-11741292
KRTAP10-10 [P60014]3EBI-3867333,EBI-11955579
KRTAP10-11 [P60412]3EBI-3867333,EBI-10217483
KRTAP10-5 [P60370]3EBI-3867333,EBI-10172150
KRTAP10-7 [P60409]3EBI-3867333,EBI-10172290
KRTAP10-8 [P60410]6EBI-3867333,EBI-10171774
KRTAP10-9 [P60411]3EBI-3867333,EBI-10172052
KRTAP11-1 [Q8IUC1]3EBI-3867333,EBI-1052037
KRTAP12-1 [P59990]3EBI-3867333,EBI-10210845
KRTAP12-2 [P59991]3EBI-3867333,EBI-10176379
KRTAP12-3 [P60328]3EBI-3867333,EBI-11953334
KRTAP12-4 [P60329]3EBI-3867333,EBI-10176396
KRTAP13-2 [Q52LG2]3EBI-3867333,EBI-11953846
KRTAP13-3 [Q3SY46]3EBI-3867333,EBI-10241252
KRTAP13-4 [Q3LI77]3EBI-3867333,EBI-11953996
KRTAP15-1 [Q3LI76]3EBI-3867333,EBI-11992140
KRTAP19-1 [Q8IUB9]3EBI-3867333,EBI-12811111
KRTAP19-2 [Q3LHN2]3EBI-3867333,EBI-12196745
KRTAP19-3 [Q7Z4W3]3EBI-3867333,EBI-12020132
KRTAP19-5 [Q3LI72]3EBI-3867333,EBI-1048945
KRTAP19-6 [Q3LI70]3EBI-3867333,EBI-12805508
KRTAP19-7 [Q3SYF9]3EBI-3867333,EBI-10241353
KRTAP2-4 [Q9BYR9]3EBI-3867333,EBI-14065470
KRTAP26-1 [Q6PEX3]3EBI-3867333,EBI-3957672
KRTAP3-1 [Q9BYR8]3EBI-3867333,EBI-9996449
KRTAP3-3 [Q9BYR6]3EBI-3867333,EBI-3957694
KRTAP4-11 [Q9BYQ6]3EBI-3867333,EBI-10302392
KRTAP4-12 [Q9BQ66]3EBI-3867333,EBI-739863
KRTAP4-2 [Q9BYR5]3EBI-3867333,EBI-10172511
KRTAP4-4 [Q9BYR3]4EBI-3867333,EBI-11958132
KRTAP4-5 [Q9BYR2]3EBI-3867333,EBI-11993254
KRTAP5-11 [Q6L8G4]3EBI-3867333,EBI-11993296
KRTAP5-3 [Q6L8H2]3EBI-3867333,EBI-11974251
KRTAP5-4 [Q6L8H1]3EBI-3867333,EBI-11963072
KRTAP5-6 [Q6L8G9]6EBI-3867333,EBI-10250562
KRTAP5-7 [Q6L8G8]3EBI-3867333,EBI-11987425
KRTAP5-9 [P26371]3EBI-3867333,EBI-3958099
KRTAP6-1 [Q3LI64]6EBI-3867333,EBI-12111050
KRTAP6-2 [Q3LI66]8EBI-3867333,EBI-11962084
KRTAP8-1 [Q8IUC2]3EBI-3867333,EBI-10261141
KRTAP9-2 [Q9BYQ4]3EBI-3867333,EBI-1044640
KRTAP9-3 [Q9BYQ3]3EBI-3867333,EBI-1043191
KRTAP9-8 [Q9BYQ0]7EBI-3867333,EBI-11958364
KSR2 [Q6VAB6]3EBI-3867333,EBI-6424389
LAGE3 [Q14657]3EBI-3867333,EBI-1052105
LASP1 - isoform 2 [Q14847-2]8EBI-3867333,EBI-9088686
LCE1A [Q5T7P2]6EBI-3867333,EBI-11962058
LCE1B [Q5T7P3]3EBI-3867333,EBI-10245913
LCE1C [Q5T751]3EBI-3867333,EBI-12224199
LCE1D [Q5T752]3EBI-3867333,EBI-11741311
LCE1E [Q5T753]3EBI-3867333,EBI-11955335
LCE1F [Q5T754]6EBI-3867333,EBI-11958008
LCE2A [Q5TA79]3EBI-3867333,EBI-10246607
LCE2B [O14633]6EBI-3867333,EBI-11478468
LCE2C [Q5TA81]4EBI-3867333,EBI-11973993
LCE2D [Q5TA82]3EBI-3867333,EBI-10246750
LCE3A [Q5TA76]9EBI-3867333,EBI-9394625
LCE3B [Q5TA77]3EBI-3867333,EBI-11974495
LCE3C [Q5T5A8]6EBI-3867333,EBI-10245291
LCE3D [Q9BYE3]8EBI-3867333,EBI-6658837
LCE3E [Q5T5B0]8EBI-3867333,EBI-10245456
LCE4A [Q5TA78]7EBI-3867333,EBI-10246358
LCE5A [Q5TCM9]6EBI-3867333,EBI-11955689
LENG8 [Q96PV6]3EBI-3867333,EBI-739546
LGALS9C [Q6DKI2]3EBI-3867333,EBI-9088829
LMF2 - isoform 2 [Q9BU23-2]3EBI-3867333,EBI-12132296
LMNTD2 [Q8IXW0]3EBI-3867333,EBI-12028858
LMO3 - isoform 4 [Q8TAP4-4]3EBI-3867333,EBI-11742507
LMO4 [P61968]3EBI-3867333,EBI-2798728
LNX1 [Q8TBB1]3EBI-3867333,EBI-739832
LONRF1 [Q17RB8]3EBI-3867333,EBI-2341787
LONRF3 [Q496Y0]3EBI-3867333,EBI-2690768
LRFN4 [Q6PJG9]3EBI-3867333,EBI-7910762
LRRC29 [Q8WV35]3EBI-3867333,EBI-10276755
LRRC41 [Q15345]3EBI-3867333,EBI-721408
LRRN4 [Q8WUT4]3EBI-3867333,EBI-745046
LYVE1 [Q9Y5Y7]3EBI-3867333,EBI-10329546
MAP11 [Q8WVR3]3EBI-3867333,EBI-719893
MAPKBP1 [O60336]3EBI-3867333,EBI-947402
MCRS1 [Q96EZ8]3EBI-3867333,EBI-348259
MED25 [Q71SY5]3EBI-3867333,EBI-394558
MELTF - isoform 2 [P08582-2]3EBI-3867333,EBI-10195914
MEOX2 [Q6FHY5]3EBI-3867333,EBI-16439278
MFSD13A [Q14CX5]3EBI-3867333,EBI-12120958
MGC50722 [Q8IVT4]3EBI-3867333,EBI-14086479
MIIP [Q5JXC2]3EBI-3867333,EBI-2801965
MKRN3 [Q13064]3EBI-3867333,EBI-2340269
MRPL23 [Q16540]3EBI-3867333,EBI-1046141
MRPL40 [Q9NQ50]3EBI-3867333,EBI-1053902
MSRB1 [Q9NZV6]3EBI-3867333,EBI-12330065
MT1M [Q8N339]3EBI-3867333,EBI-3911571
MTA1 [Q13330]3EBI-3867333,EBI-714236
MTNR1A [P48039]3EBI-3867333,EBI-1188238
MXD3 [Q9BW11]3EBI-3867333,EBI-741574
MXI1 - isoform 3 [P50539-3]3EBI-3867333,EBI-10211940
MYPOP [Q86VE0]3EBI-3867333,EBI-2858213
NDUFA9 [Q16795]3EBI-3867333,EBI-1045087
NDUFAF3 [Q9BU61]3EBI-3867333,EBI-2114801
NDUFV1 [P49821]3EBI-3867333,EBI-748312
NECTIN2 - isoform Alpha [Q92692-2]3EBI-3867333,EBI-6979889
NECTIN3 - isoform 2 [Q9NQS3-2]3EBI-3867333,EBI-12106440
NEU2 [Q9Y3R4]3EBI-3867333,EBI-10327976
NEU4 - isoform 2 [Q8WWR8-2]3EBI-3867333,EBI-10277551
NKD1 [Q969G9]3EBI-3867333,EBI-1538217
NMU [P48645]3EBI-3867333,EBI-10210351
NOTCH2NLC [P0DPK4]3EBI-3867333,EBI-22310682
NOXA1 - isoform 2 [Q86UR1-2]3EBI-3867333,EBI-12025760
NPBWR2 [P48146]3EBI-3867333,EBI-10210114
NPDC1 [Q9NQX5]3EBI-3867333,EBI-748927
NPPB [P16860]3EBI-3867333,EBI-747044
NPTN - isoform 1 [Q9Y639-1]3EBI-3867333,EBI-12839590
NR1D2 [Q6NSM0]3EBI-3867333,EBI-10250949
NR4A3 [Q92570]3EBI-3867333,EBI-13644623
NSD1 - isoform 2 [Q96L73-2]3EBI-3867333,EBI-11110981
NTN4 [Q9HB63]3EBI-3867333,EBI-743459
NUBP2 [Q9Y5Y2]3EBI-3867333,EBI-1048886
NUFIP2 [Q7Z417]3EBI-3867333,EBI-1210753
ODF3L1 [Q8IXM7]3EBI-3867333,EBI-13331299
OLIG3 [Q7RTU3]3EBI-3867333,EBI-10225049
OR7A17 [O14581]3EBI-3867333,EBI-13329281
OTOS [Q8NHW6]3EBI-3867333,EBI-12038159
OTX1 [P32242]3EBI-3867333,EBI-740446
P2RX7 [Q99572]3EBI-3867333,EBI-1753251
PATZ1 - isoform 4 [Q9HBE1-4]3EBI-3867333,EBI-11022007
PCSK5 - isoform PC6A [Q92824-2]3EBI-3867333,EBI-11956269
PDE9A - isoform PDE9A2 [O76083-2]3EBI-3867333,EBI-11524542
PGAP2 - isoform 5 [Q9UHJ9-5]3EBI-3867333,EBI-12092917
PHETA1 - isoform 4 [Q8N4B1-4]3EBI-3867333,EBI-14131832
PHLDA1 [A2BDE7]3EBI-3867333,EBI-14084211
PITX1 [P78337]3EBI-3867333,EBI-748265
PITX2 - isoform PTX2C [Q99697-2]3EBI-3867333,EBI-12138495
PKD2 [Q13563]3EBI-3867333,EBI-7813714
PKN1 [Q16512]3EBI-3867333,EBI-602382
PLA2G10 [O15496]3EBI-3867333,EBI-726466
PLEKHN1 - isoform 3 [Q494U1-3]3EBI-3867333,EBI-12014286
PLLP [Q9Y342]4EBI-3867333,EBI-3919291
POLD1 [P28340]3EBI-3867333,EBI-716569
POU4F2 [Q12837]3EBI-3867333,EBI-17236143
PPP1CB [P62140]3EBI-3867333,EBI-352350
PPP1R32 - isoform 2 [Q7Z5V6-2]3EBI-3867333,EBI-12000762
PPY [P01298]3EBI-3867333,EBI-12121422
PRF1 [P14222]3EBI-3867333,EBI-724466
PRKAA2 [P54646]3EBI-3867333,EBI-1383852
PRKAB2 [O43741]4EBI-3867333,EBI-1053424
PROC [P04070]3EBI-3867333,EBI-1383018
PROP1 [O75360]3EBI-3867333,EBI-9027467
PRPF31 [Q8WWY3]3EBI-3867333,EBI-1567797
PRR19 - isoform 2 [A6NJB7-2]3EBI-3867333,EBI-11998870
PRR30 [Q53SZ7]3EBI-3867333,EBI-12360827
PRR34 [Q9NV39]3EBI-3867333,EBI-11959565
PRR35 [P0CG20]3EBI-3867333,EBI-11986293
PTGDS [P41222]3EBI-3867333,EBI-948821
PTPMT1 [Q8WUK0]3EBI-3867333,EBI-7199479
PVR [P15151]3EBI-3867333,EBI-3919694
QRICH1 [Q2TAL8]3EBI-3867333,EBI-2798044
R3HDM2 [Q9Y2K5]3EBI-3867333,EBI-948428
RAB3IL1 [Q8TBN0]3EBI-3867333,EBI-743796
RALGDS - isoform 6 [Q12967-6]3EBI-3867333,EBI-12005546
RAMAC [Q9BTL3]3EBI-3867333,EBI-744023
RAMP3 [O60896]6EBI-3867333,EBI-720447
RASD1 [Q9Y272]3EBI-3867333,EBI-740818
RBM22 [Q9NW64]3EBI-3867333,EBI-2602260
RBP3 [P10745]3EBI-3867333,EBI-12806054
RECK [Q6P9E2]3EBI-3867333,EBI-10253121
REM2 [Q8IYK8]3EBI-3867333,EBI-11304833
RGL2 [O15211]3EBI-3867333,EBI-712355
RGS3 - isoform 4 [P49796-4]3EBI-3867333,EBI-12006708
RHBG - isoform 3 [Q9H310-3]3EBI-3867333,EBI-12006870
RHNO1 [Q9BSD3]3EBI-3867333,EBI-9658624
RNF38 [Q9H0F5]3EBI-3867333,EBI-2341200
RPS19BP1 [Q86WX3]3EBI-3867333,EBI-4479407
RPUSD3 [Q6P087]3EBI-3867333,EBI-5458784
RSPO2 - isoform 2 [Q6UXX9-2]3EBI-3867333,EBI-12009390
SAPCD2 [Q86UD0]3EBI-3867333,EBI-2561646
SAXO1 [Q8IYX7]3EBI-3867333,EBI-3957636
SCARF1 [Q14162]3EBI-3867333,EBI-12056025
SCNM1 [Q9BWG6]3EBI-3867333,EBI-748391
SEMA3B - isoform 2 [Q13214-2]3EBI-3867333,EBI-11017428
SEMA4C [Q9C0C4]3EBI-3867333,EBI-10303490
SH3KBP1 [Q96B97]3EBI-3867333,EBI-346595
SH3RF2 [Q8TEC5]3EBI-3867333,EBI-2130111
SHFL - isoform 4 [Q9NUL5-4]3EBI-3867333,EBI-11955083
SHISA6 [Q6ZSJ9]3EBI-3867333,EBI-12037847
SLC12A4 [Q9UP95]3EBI-3867333,EBI-7244836
SLC13A5 [Q86YT5]3EBI-3867333,EBI-12002412
SLC23A1 - isoform 3 [Q9UHI7-3]3EBI-3867333,EBI-11998660
SLC25A18 [Q9H1K4]3EBI-3867333,EBI-6269587
SLC25A48 - isoform 3 [Q6ZT89-3]3EBI-3867333,EBI-12065614
SLC43A2 [Q8N370]3EBI-3867333,EBI-10265149
SLC5A5 [Q92911]3EBI-3867333,EBI-12313867
SLC6A20 [Q9NP91]3EBI-3867333,EBI-10311198
SLIT1 [O75093]3EBI-3867333,EBI-947791
SMARCC1 [Q92922]3EBI-3867333,EBI-355653
SMARCD1 [Q96GM5]3EBI-3867333,EBI-358489
SMARCE1 [Q969G3]3EBI-3867333,EBI-455078
SMCP [P49901]6EBI-3867333,EBI-750494
SMOC1 - isoform 2 [Q9H4F8-2]3EBI-3867333,EBI-12162539
SMRP1 [Q8NCR6]3EBI-3867333,EBI-10269322
SMUG1 - isoform 2 [Q53HV7-2]3EBI-3867333,EBI-12275818
SNRPB - isoform SM-B [P14678-2]3EBI-3867333,EBI-372475
SNRPC [P09234]3EBI-3867333,EBI-766589
SNX18 [Q96RF0]3EBI-3867333,EBI-298169
SNX26 [A1A5D2]3EBI-3867333,EBI-14550815
SOCS7 [O14512]3EBI-3867333,EBI-1539606
SPATA24 - isoform 2 [Q86W54-2]3EBI-3867333,EBI-12041693
SPATA3 [A0A024R4B0]3EBI-3867333,EBI-14123856
SPATA46 [Q5T0L3]3EBI-3867333,EBI-750105
SPATA8 [Q6RVD6]3EBI-3867333,EBI-8635958
SPEF1 - isoform 2 [Q9Y4P9-2]3EBI-3867333,EBI-12303571
SPG7 [Q9UQ90]3EBI-3867333,EBI-717201
SPON1 [Q9HCB6]3EBI-3867333,EBI-2431846
SPPL2C [Q8IUH8]3EBI-3867333,EBI-14064968
SPRY1 [O43609]6EBI-3867333,EBI-3866665
SPTSSA [Q969W0]3EBI-3867333,EBI-723396
SRD5A2 [P31213]3EBI-3867333,EBI-13130472
STK16 [O75716]3EBI-3867333,EBI-749295
TAPBPL [Q9BX59]3EBI-3867333,EBI-12017416
TBX2 [Q13207]3EBI-3867333,EBI-2853051
TBX6 [O95947]3EBI-3867333,EBI-2824328
TCAF1 - isoform 2 [Q9Y4C2-2]3EBI-3867333,EBI-11974855
TCEA2 [Q15560]3EBI-3867333,EBI-710310
TCEANC - isoform 2 [Q8N8B7-2]3EBI-3867333,EBI-11955057
TCF7L2 - isoform 10 [Q9NQB0-10]3EBI-3867333,EBI-11746252
TENT5B [Q96A09]3EBI-3867333,EBI-752030
TEPSIN [Q96N21]3EBI-3867333,EBI-11139477
TEX37 [Q96LM6]3EBI-3867333,EBI-743976
TEX45 [Q8NA69]3EBI-3867333,EBI-12021638
TFAP2D [Q7Z6R9]3EBI-3867333,EBI-11952651
TGFB1 [P01137]3EBI-3867333,EBI-779636
THAP7 [Q9BT49]3EBI-3867333,EBI-741350
TIMM22 [Q9Y584]3EBI-3867333,EBI-1200494
TLE5 - isoform 2 [Q08117-2]3EBI-3867333,EBI-11741437
TM7SF2 [O76062]3EBI-3867333,EBI-2115348
TMEM174 [Q8WUU8]3EBI-3867333,EBI-10276729
TMEM8A [Q9HCN3]3EBI-3867333,EBI-10310808
TNIP1 [Q15025]3EBI-3867333,EBI-357849
TNIP3 [Q96KP6]3EBI-3867333,EBI-2509913
TNK2 - isoform 2 [Q07912-2]3EBI-3867333,EBI-11994780
TNS4 [Q8IZW8]3EBI-3867333,EBI-7543499
TREX1 - isoform 1 [Q9NSU2-1]3EBI-3867333,EBI-16746122
TRIM42 [Q8IWZ5]3EBI-3867333,EBI-5235829
TSGA10IP [Q3SY00]3EBI-3867333,EBI-10241197
TSPAN4 [O14817]6EBI-3867333,EBI-8652667
TTC23 - isoform 3 [Q5W5X9-3]3EBI-3867333,EBI-9090990
TTPA [P49638]3EBI-3867333,EBI-10210710
TYK2 [P29597]3EBI-3867333,EBI-1383454
UBXN7 [O94888]3EBI-3867333,EBI-1993627
UNC5CL [Q8IV45]3EBI-3867333,EBI-12238241
USP54 - isoform 6 [Q70EL1-9]3EBI-3867333,EBI-11975223
UTP23 [Q9BRU9]3EBI-3867333,EBI-5457544
VASN [Q6EMK4]6EBI-3867333,EBI-10249550
VENTX [O95231]3EBI-3867333,EBI-10191303
VGLL3 - isoform 2 [A8MV65-2]3EBI-3867333,EBI-11957216
VSTM4 [Q8IW00]3EBI-3867333,EBI-4311759
VWC2 [Q2TAL6]3EBI-3867333,EBI-11957238
VWC2L [B2RUY7]3EBI-3867333,EBI-11747707
WDR25 - isoform 2 [Q64LD2-2]4EBI-3867333,EBI-12032042
WDYHV1 [Q96HA8]3EBI-3867333,EBI-741158
WIF1 [Q9Y5W5]3EBI-3867333,EBI-3922719
WNT11 [O96014]3EBI-3867333,EBI-8058160
WT1 - isoform 6 [P19544-6]3EBI-3867333,EBI-11745701
YES1 [P07947]3EBI-3867333,EBI-515331
YY1 [P25490]3EBI-3867333,EBI-765538
ZBTB25 [P24278]3EBI-3867333,EBI-739899
ZBTB4 [Q9P1Z0]3EBI-3867333,EBI-2564133
ZCCHC14 [Q8WYQ9]3EBI-3867333,EBI-3937908
ZDHHC1 [Q8WTX9]3EBI-3867333,EBI-2818796
ZFHX2 [A2RRC6]3EBI-3867333,EBI-11994144
ZIC1 [Q15915]3EBI-3867333,EBI-11963196
ZMYND10 [O75800]3EBI-3867333,EBI-747061
ZNF124 [Q15973]3EBI-3867333,EBI-2555767
ZNF165 [P49910]3EBI-3867333,EBI-741694
ZNF266 [Q14584]3EBI-3867333,EBI-7115319
ZNF319 [Q9P2F9]3EBI-3867333,EBI-11993110
ZNF330 [Q9Y3S2]3EBI-3867333,EBI-373456
ZNF408 [Q9H9D4]3EBI-3867333,EBI-347633
ZNF414 [Q96IQ9]3EBI-3867333,EBI-744257
ZNF417 [Q8TAU3]5EBI-3867333,EBI-740727
ZNF419 [Q96HQ0]3EBI-3867333,EBI-10288482
ZNF438 [Q7Z4V0]3EBI-3867333,EBI-11962468
ZNF439 [Q8NDP4]3EBI-3867333,EBI-747580
ZNF440 [Q8IYI8]3EBI-3867333,EBI-726439
ZNF441 [Q8N8Z8]3EBI-3867333,EBI-17216366
ZNF446 - isoform 2 [Q9NWS9-2]3EBI-3867333,EBI-740232
ZNF497 [Q6ZNH5]3EBI-3867333,EBI-10486136
ZNF552 [Q9H707]3EBI-3867333,EBI-2555731
ZNF575 [Q86XF7]3EBI-3867333,EBI-14069183
ZNF580 [Q9UK33]3EBI-3867333,EBI-746277
ZNF581 [Q9P0T4]6EBI-3867333,EBI-745520
ZNF587 [Q96SQ5]3EBI-3867333,EBI-6427977
ZNF648 [Q5T619]3EBI-3867333,EBI-11985915
ZNF669 [Q96BR6]3EBI-3867333,EBI-12006574
ZNF683 [Q8IZ20]3EBI-3867333,EBI-12005952
ZNF696 [Q9H7X3]3EBI-3867333,EBI-11090299
ZNF764 [Q96H86]3EBI-3867333,EBI-745775
ZNF775 [Q96BV0]3EBI-3867333,EBI-7149881
ZNF786 [Q8N393]4EBI-3867333,EBI-10265203
ZNF835 [Q9Y2P0]3EBI-3867333,EBI-5667516
ZNF837 [Q96EG3]3EBI-3867333,EBI-11962574
ZNF843 [Q8N446]3EBI-3867333,EBI-6428016
ZNHIT1 [O43257]3EBI-3867333,EBI-347522
ZSCAN5A [Q9BUG6]3EBI-3867333,EBI-8836980

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
132001, 9 interactors

Protein interaction database and analysis system

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IntActi
A8MQ03, 501 interactors

STRING: functional protein association networks

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STRINGi
9606.ENSP00000386453

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

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RNActi
A8MQ03 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi118 – 141Cys-richAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CYSRT1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410JEBP Eukaryota
ENOG41114BU LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000003233

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
A8MQ03

Database of Orthologous Groups

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OrthoDBi
1474726at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
A8MQ03

TreeFam database of animal gene trees

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TreeFami
TF338434

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR018904 UPF0574

The PANTHER Classification System

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PANTHERi
PTHR37879 PTHR37879, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF10631 DUF2477, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A8MQ03-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPQEMVVKN PYAHISIPRA HLRPDLGQQL EVASTCSSSS EMQPLPVGPC
60 70 80 90 100
APEPTHLLQP TEVPGPKGAK GNQGAAPIQN QQAWQQPGNP YSSSQRQAGL
110 120 130 140
TYAGPPPAGR GDDIAHHCCC CPCCHCCHCP PFCRCHSCCC CVIS
Length:144
Mass (Da):15,313
Last modified:December 4, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i58C43B5472CA49EF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B8A4K4B8A4K4_HUMAN
Cysteine-rich tail protein 1
CYSRT1
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti108A → V in AAH52297 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX255925 Genomic DNA No translation available.
BC052297 mRNA Translation: AAH52297.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS48064.2

NCBI Reference Sequences

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RefSeqi
NP_945352.3, NM_199001.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000650725; ENSP00000498316; ENSG00000197191

Database of genes from NCBI RefSeq genomes

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GeneIDi
375791

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:375791

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX255925 Genomic DNA No translation available.
BC052297 mRNA Translation: AAH52297.1
CCDSiCCDS48064.2
RefSeqiNP_945352.3, NM_199001.3

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi132001, 9 interactors
IntActiA8MQ03, 501 interactors
STRINGi9606.ENSP00000386453

PTM databases

iPTMnetiA8MQ03
PhosphoSitePlusiA8MQ03
SwissPalmiA8MQ03

Polymorphism and mutation databases

BioMutaiCYSRT1

Proteomic databases

EPDiA8MQ03
jPOSTiA8MQ03
MassIVEiA8MQ03
MaxQBiA8MQ03
PaxDbiA8MQ03
PRIDEiA8MQ03
ProteomicsDBi1929

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
8700 53 antibodies

Genome annotation databases

EnsembliENST00000650725; ENSP00000498316; ENSG00000197191
GeneIDi375791
KEGGihsa:375791

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
375791

GeneCards: human genes, protein and diseases

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GeneCardsi
CYSRT1
HGNCiHGNC:30529 CYSRT1
neXtProtiNX_A8MQ03
OpenTargetsiENSG00000197191
PharmGKBiPA162380848

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JEBP Eukaryota
ENOG41114BU LUCA
GeneTreeiENSGT00390000003233
InParanoidiA8MQ03
OrthoDBi1474726at2759
PhylomeDBiA8MQ03
TreeFamiTF338434

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CYSRT1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
375791
PharosiA8MQ03 Tdark

Protein Ontology

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PROi
PR:A8MQ03
RNActiA8MQ03 protein

Gene expression databases

ExpressionAtlasiA8MQ03 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR018904 UPF0574
PANTHERiPTHR37879 PTHR37879, 1 hit
PfamiView protein in Pfam
PF10631 DUF2477, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCRTP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8MQ03
Secondary accession number(s): Q86UY7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 4, 2007
Last modified: April 22, 2020
This is version 85 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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