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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Enzyme and pathway databases

BioCyciCMAQ397948:G1GA9-1983-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Cmaq_1916
OrganismiCaldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Taxonomic identifieri397948 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeCaldivirga
Proteomesi
  • UP000001137 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000884771 – 512Phosphoenolpyruvate carboxylaseAdd BLAST512

Proteomic databases

PRIDEiA8MBK0

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi397948.Cmaq_1916

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
HOGENOMiHOG000038601
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

A8MBK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRIIPRTMCT QHPDYANVPQ WVVNDFIKGD DEVYEAYMNY SIYDCQETMW
60 70 80 90 100
DFEGKDVDIY VVRKLLENYG GFFINKVLGE DIYLTYRLPN PNVEASDRKI
110 120 130 140 150
FAEALETIPM AYDLARVFYG KPVKAIFEVI FPLTSSSRDL IMTLRYYERI
160 170 180 190 200
VAGKCSVELD DGLKVSDVIG EVEPKTIEVI PLVEDMESLV RIDSIIEGYV
210 220 230 240 250
KVAKPQYLRV FIARSDPAMN YGLIPAVLLA KIALSRVYAI GNSLGLSIYP
260 270 280 290 300
IIGVGPTPFR GNFNPRNVNN TLKEYPGVYT FTVQSAFRYD YPVDNAKDAI
310 320 330 340 350
NLINNSKPTE PVILSSDEEE LALTIIRQYT DRYQAEVEGL ANAVNYIAQL
360 370 380 390 400
LPPRRTRRLH IGLFGYGRGF RGVTLPRAIA FVGALYSIGI PPEILGLSTL
410 420 430 440 450
LKLNERQWGV LEGNYVNLWS DLSDAAQYIC MECIEQLPSM KSELRVSKET
460 470 480 490 500
IAMVLEDIKA IDELGVKVSS PGFEQRKHAL LTKLFLESVN NSYINDAKAY
510
LLDMAKVRRA IG
Length:512
Mass (Da):57,872
Last modified:December 4, 2007 - v1
Checksum:iE8B4DF81D2E0A96F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000852 Genomic DNA Translation: ABW02733.1
RefSeqiWP_012186952.1, NC_009954.1

Genome annotation databases

EnsemblBacteriaiABW02733; ABW02733; Cmaq_1916
GeneIDi5709298
KEGGicma:Cmaq_1916

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000852 Genomic DNA Translation: ABW02733.1
RefSeqiWP_012186952.1, NC_009954.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi397948.Cmaq_1916

Proteomic databases

PRIDEiA8MBK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABW02733; ABW02733; Cmaq_1916
GeneIDi5709298
KEGGicma:Cmaq_1916

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
HOGENOMiHOG000038601
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Enzyme and pathway databases

BioCyciCMAQ397948:G1GA9-1983-MONOMER

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCAPPA_CALMQ
AccessioniPrimary (citable) accession number: A8MBK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: October 10, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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