Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Salinispora arenicola (strain CNS-205)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei57NucleophileUniRule annotation1
Binding sitei118SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processtRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSARE391037:G1GA7-4327-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Sare_4284Imported
OrganismiSalinispora arenicola (strain CNS-205)Imported
Taxonomic identifieri391037 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeSalinispora
Proteomesi
  • UP000001153 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi391037.Sare_4284

Structurei

3D structure databases

ProteinModelPortaliA8M4Z8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 254PseudoU_synth_1InterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

A8M4Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQERTRVRLD VSYDGTDFSG WAVQPDRRTV AGVLVQAFDL VLGSDAATGL
60 70 80 90 100
TVAGRTDAGV HATGQVCHVD LLTEVWRRHE GTLLRRLARL LPGDVRVRAV
110 120 130 140 150
TGVPGDFDAR FSATFRRYEY RVTDAPWGAE PLRRHDTLAW SSRLDQDALN
160 170 180 190 200
AAADGLVGEH DFAAYCRRKE NATTLREVTR LDWRRSADGV LVATVQADAF
210 220 230 240 250
CQAMVRSLVG AMLVVGDGRR PAGWPAGLLA RRERANEVNV APAHGLTLVA
260 270
VGYPDDPAGY ADRATRTRRL RVPPDA
Length:276
Mass (Da):30,253
Last modified:December 4, 2007 - v1
Checksum:i87A838C2D6649F13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000850 Genomic DNA Translation: ABW00066.1
RefSeqiWP_012184302.1, NC_009953.1

Genome annotation databases

EnsemblBacteriaiABW00066; ABW00066; Sare_4284
GeneIDi5706996
KEGGisaq:Sare_4284
PATRICifig|391037.6.peg.4325

Similar proteinsi

Entry informationi

Entry nameiA8M4Z8_SALAI
AccessioniPrimary (citable) accession number: A8M4Z8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: July 18, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health