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1 to 21 of 21  Show
  1. 1
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Trachea.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Placenta.
    Source: UniProtKB/TrEMBL (unreviewed).
  3. 3
    "Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft."
    Gao L., Aizaki H., He J.W., Lai M.M.
    J. Virol. 78:3480-3488(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Annotation: protein-protein interactions among the various HCV NS proteins and hVAP-33 are important for the formation of HCV replication complexImported.
    Source: GeneRIF:9218.

    This publication is mapped to 1 other entry.

  4. 4
    "Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder."
    Lohoff F.W., Weller A.E., Bloch P.J., Nall A.H., Ferraro T.N., Berrettini W.H.
    J Neural Transm (Vienna) 115:1339-1345(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Our results provide suggestive evidence of an association between SNPs in the 3'UTR of the VAPA gene and bipolar disorder; Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 1 other entry.

  5. 5
    "FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation."
    Prosser D.C., Tran D., Gougeon P.Y., Verly C., Ngsee J.K.
    J. Cell. Sci. 121:3052-3061(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Data show that overexpression of VAPA and VAPB causes retention of ER membrane proteins by impeding lateral diffusion and their incorporation into transport vesicles.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 8 other entries.

  6. 6
    "Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein."
    Saita S., Shirane M., Natume T., Iemura S., Nakayama K.I.
    J. Biol. Chem. 284:13766-13777(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: VAP-A is an important regulator both of the subcellular localization of protrudin and of its ability to stimulate neurite outgrowth.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 3 and mapped to 11 other entries.

  7. 7
    "The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A."
    Tuuf J., Wistbacka L., Mattjus P.
    Biochem. Biophys. Res. Commun. 388:395-399(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: GLTP and VAP-A were shown to interact.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 6 other entries.

  8. 8
    "Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies."
    Furuita K., Jee J., Fukada H., Mishima M., Kojima C.
    J. Biol. Chem. 285:12961-12970(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Structure.
    Annotation: Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 1 and mapped to 1 other entries.

  9. 9
    "Human VAPA and the yeast VAP Scs2p with an altered proline distribution can phenocopy amyotrophic lateral sclerosis-associated VAPB(P56S)."
    Nakamichi S., Yamanaka K., Suzuki M., Watanabe T., Kagiwada S.
    Biochem. Biophys. Res. Commun. 404:605-609(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: three conserved prolines in VAPA and Scs2p confers less vulnerability to mutations equivalent to the amyotrophic lateral sclerosis causing mutation as compared with VAPB which has only two conserved prolines.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 9 other entries.

  10. 10
    "Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome."
    Tsui D.W., Lam Y.M., Lee W.S., Leung T.Y., Lau T.K., Lau E.T., Tang M.H., Akolekar R., Nicolaides K.H., Chiu R.W., Lo Y.M., Chim S.S.
    PLoS ONE 5:e15069-e15069(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Data show that the methylated VAPA-APCDD1 DNA in maternal plasma is predominantly derived from the fetus and this novel fetal epigenetic marker in maternal plasma is useful for the noninvasive detection of fetal trisomy 18.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 2 other entries.

  11. 11
    "Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33."
    Wang S., Wu X., Pan T., Song W., Wang Y., Zhang F., Yuan Z.
    J. Gen. Virol. 93:83-92(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein VAP-33.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 1 and mapped to 3 other entries.

  12. 12
    "STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER."
    Alpy F., Rousseau A., Schwab Y., Legueux F., Stoll I., Wendling C., Spiegelhalter C., Kessler P., Mathelin C., Rio M.C., Levine T.P., Tomasetto C.
    J. Cell Sci. 126:5500-5512(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the endoplasmic reticulum.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 3 and mapped to 7 other entries.

  13. 13
    "GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication."
    Xu G., Xin X., Zheng C.
    PLoS ONE 8:E78195-E78195(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: GPS2 is required for the association of viral NS5A with VAP-A and hepatitis C virus replication.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 1 and mapped to 2 other entries.

  14. 14
    "Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells."
    Kumagai K., Kawano-Kawada M., Hanada K.
    J. Biol. Chem. 289:10748-10760(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: phosphorylation of CERT at the FFAT motif-adjacent serine affects its affinity for VAP which may regulate the inter-organelle trafficking of ceramide in response to the perturbation of cellular sphingomyelin and/or other sphingolipidsImported.
    Source: GeneRIF:9218.

    This publication is mapped to 4 other entries.

  15. 15
    Category: Interaction.
    Source: IntAct:A8KA83.

    This publication is mapped to 4117 other entries.

  16. 16
    "OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity."
    Weber-Boyvat M., Kentala H., Lilja J., Vihervaara T., Hanninen R., Zhou Y., Peranen J., Nyman T.A., Ivaska J., Olkkonen V.M.
    Exp. Cell Res. 331:278-291(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: phosphorylation of ORP3 controls its association with VAPA. Furthermore ORP3-VAPA complexes stimulate R-Ras signaling.Imported.
    Source: GeneRIF:9218.

    This publication is cited by 1 other entry.

  17. 17
    "Sterol liganding of OSBP-related proteins (ORPs) regulates the subcellular distribution of ORP-VAPA complexes and their impacts on organelle structure."
    Kentala H., Pfisterer S.G., Olkkonen V.M., Weber-Boyvat M.
    Steroids 99:248-258(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: The effects of sterol manipulation of HuH7 cells on complexes of established sterol-binding Oxysterol-binding protein related proteins with their endoplasmic reticulum receptor VAMP-associated protein A (VAPA) were examined.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 1 other entry.

  18. 18
    "CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface."
    Wakana Y., Kotake R., Oyama N., Murate M., Kobayashi T., Arasaki K., Inoue H., Tagaya M.
    Mol. Biol. Cell 26:4686-4699(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Our work revealed that VAP-A/B knockdown impaired the processing and secretion of PAUF which is one of the cargo proteins of carriers of the trans-Golgi network to the cell surface.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 8 other entries.

  19. 19
    "Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P."
    Dong R., Saheki Y., Swarup S., Lucast L., Harper J.W., De Camilli P.
    Cell 166:408-423(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location.
    Annotation: Effects of the combined absence of VAPA and VAPB in human cells were studied; cells lacking VAP accumulate high levels of PI4P actin comets and trans-Golgi proteins on endosomes. Such defects are mimicked by downregulation of OSBP a VAP interactor and PI4P transporter that participates in VAP-dependent endoplasmic reticulum-endosomes tethers.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 8 other entries.

  20. 20
    "VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis."
    Hua R., Cheng D., Coyaud E., Freeman S., Di Pietro E., Wang Y., Vissa A., Yip C.M., Fairn G.D., Braverman N., Brumell J.H., Trimble W.S., Raught B., Kim P.K.
    J. Cell Biol. 216:367-377(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: VAP-ACBD5-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 13 other entries.

  21. 21
    "Model of OSBP-Mediated Cholesterol Supply to Aichi Virus RNA Replication Sites Involving Protein-Protein Interactions among Viral Proteins, ACBD3, OSBP, VAP-A/B, and SAC1."
    Ishikawa-Sasaki K., Nagashima S., Taniguchi K., Sasaki J.
    J. Virol. 92:0-0(2018) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: the component proteins of the machinery OSBP VAP SAC1 and PITPNB are all essential host factors for AiV replication. Importantly the machinery is directly recruited to the RNA replication sites through previously unknown interactions of VAP/OSBP/SAC1 with the AiV proteins and with ACBD3.Imported.
    Source: GeneRIF:9218.

    This publication is mapped to 18 other entries.

1 to 21 of 21  Show
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