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Protein
Submitted name:

cDNA FLJ78586, highly similar to Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (VAPA), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ78586, highly similar to Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (VAPA), mRNAImported
Submitted name:
cDNA, FLJ96653, Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (VAPA), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiA8KA83
PRIDEiA8KA83

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiA8KA83, 5 interactors
MINTiA8KA83

Structurei

3D structure databases

SMRiA8KA83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 124MSPInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili165 – 192Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG028551

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR000535 MSP_dom
IPR008962 PapD-like_sf
IPR016763 VAP
IPR030229 VAPA
PANTHERiPTHR10809 PTHR10809, 1 hit
PTHR10809:SF40 PTHR10809:SF40, 1 hit
PfamiView protein in Pfam
PF00635 Motile_Sperm, 1 hit
PIRSFiPIRSF019693 VAMP-associated, 1 hit
SUPFAMiSSF49354 SSF49354, 1 hit
PROSITEiView protein in PROSITE
PS50202 MSP, 1 hit

Sequencei

Sequence statusi: Complete.

A8KA83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKHEQILVL DPPTDLKFKG PFTDVVTTNL KLRNPSDRKV CFKVKTTAPR
60 70 80 90 100
RYCVRPNSGI IDPGSTVTVS VMLQPFDYDP NEKSKHKFMV QTIFAPPNTS
110 120 130 140 150
DMEAVWKEAK PDELMDSKLR CVFEMPNEND KLNDMEPSKA VPLNASKQDG
160 170 180 190 200
PMPKPHSVSL NDTETRKLME ECKRLQGEMM KLSEENRHLR DEGLRLRKVA
210 220 230 240
HSDKPGSTST ASFRDNVTSP LPSLLVVIAA IFIGFFLGKF IL
Length:242
Mass (Da):27,318
Last modified:December 4, 2007 - v1
Checksum:i097388A3AA711419
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292948 mRNA Translation: BAF85637.1
AK315577 mRNA Translation: BAG37951.1
UniGeneiHs.165195

Similar proteinsi

Entry informationi

Entry nameiA8KA83_HUMAN
AccessioniPrimary (citable) accession number: A8KA83
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 20, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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